1α,25-Dihydroxyvitamin D3
The Influence of 1α.25-Dihydroxyvitamin D3 Coating on Implant Osseointegration in the Rabbit Tibia
... Vitamin D has been shown to play an essential role in bone mineral homeostasis and in its active form, 1α,25-dihydroxyvitamin D3 [1.25-(OH) 2 D 3 ], may act as a bioactive protein promoting ...
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Ligation of TLR9 induced on human IL 10–secreting Tregs by 1α,25 dihydroxyvitamin D3 abrogates regulatory function
... Signaling through the TLR family of molecular pattern recognition receptors has been implicated in the induc- tion of innate and adaptive immune responses. A role for TLR signaling in the maintenance and/or regulation of ...
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Influence of 1α, 25 dihydroxyvitamin D3 [1, 25(OH)2D3] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes
... Total cellular protein lysate was isolated using radio- immunopreceptation assay (RIPA) buffer (150 mM NaCl, 50 mM Tris? HCl, pH 7.5, 5 mM ethylene glycol tetraace- tic acid (EGTA), 1% Triton, 0.5% sodium deoxycholate ...
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Vlotides, George (2003): Einfluss von 17β-Östradiol und 1α,25-Dihydroxyvitamin D3 auf die Funktion von Zellen der monozytischen Zellreihe. Dissertation, LMU München: Medizinische Fakultät
... Auch im humanen Model scheint Östrogen eine ähnliche Wirkung zu haben, wobei der Effekt in mononukleären Mischkulturen deutlich stärker ist als in reinen B-Zell-Populationen (Kanda et [r] ...
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ESWT Enhances Expression of Pdia-3 which is a Key Factor of 1α,25-Dihydroxyvitamin D3 Rapid Membrane Signaling Pathway in Treatment of Early Osteoarthritis Knee
... The addition of shockwave therapy to knee resulted in increase of bone formation markers, including OPG, ALP and MMP13. The ALP increased if there was active bone formation occurring, as ALP was a byproduct of ...
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1α,25-Dihydroxyvitamin D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier
... intracellular level of cAMP in several cell lines as effi- ciently as did forskolin [30,38], and the MEK-mitogen- activated protein kinase (MAPK)-extracellular signal- regulated kinase (ERK) signaling pathway is known to ...
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Hypophosphatemic Rickets: Effect of 1α, 25-Dihydroxyvitamin D3 on Growth and Mineral Metabolism
... The failure of adequate cure of the rickets and growth retardation under the former standard treatment5 of up to 80,000 units of vitamin D2 plus 2,200 mg/day of phosphorus as buffered ph[r] ...
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The effects of 1α,25 dihydroxyvitamin D3 on matrix metalloproteinase and prostaglandin E2 production by cells of the rheumatoid lesion
... of 25-hydroxyvitamin D 3 [1]. However, the local production of 1 α ,25(OH) 2 D 3 within synovial fluids of arthritic joints, especially the macrophage component, has recently been indicated [8,9]; and ...
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The relationship between dairy intake, body composition, physical activity, and bone health among pre pubertal children : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Human Nutrition at Massey University, Palmerston North, New Zealand
... Percent body fat 1α,25- dihydroxyvitamin D3 Adequate intake Bone mineral content Bone mineral density Bone mineral density childhood study Body mass index Bone morphogenic protein Bone m[r] ...
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25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression
... Collectively these observations indicate that the link between vitamin D, muscle function and sarcopenia is more complex than originally thought, and cannot be defined simply through measurement of 25OHD3. General ...
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1α-Hydroxyvitamin D3 Treatment of Three Patients With 1,25-Dihydroxyvitamin D-Receptor-Defect Rickets and Alopecia
... The serum 1,25-(OH)2D levels in- creased markedly during the initial treatment with 1 g/kg/d of la-(OH)D, but gradually decreased during treatment with 3 or 6 tg/kg/d. During treat- ment[r] ...
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Evidence that Increased Circulating 1α,25 Dihydroxyvitamin D is the Probable Cause for Abnormal Calcium Metabolism in Sarcoidosis
... serum 25-hydroxyvitamin D (25-OHD), plasma 1 a ,25(OH) 2 D and, in some studies, calcium balance were ...Serum 25-OHD and serum calcium remained within the normal range in all subjects and ...
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1,25-Dihydroxyvitamin D3 and Development of Tuberculosis in Cattle
... were incubated in 96-well flat-bottomed plates (Nunc, Life Technologies) in triplicate with antigen (bovine tuberculin purified protein derivative [PPD-B], 10 g/ml; ESAT-6, 5 g/ml), concanavalin A (ConA) (5 g/ml), and ...
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1α, 25 dihydroxy Vitamin D3 containing fractions of Catharanthus roseus leaf aqueous extract inhibit preadipocyte differentiation and induce lipolysis in 3T3 L1 cells
... and 1α, 25-dihydroxy Vitamin D3 (Sigma D1530) on differentiation, cells were exposed to the extract or the compound from day 0 to day ...and 1α, 25-dihydroxy Vitamin D3 on mature ...
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EFFECT OF SAUDI ARABIAN Capparis Cartilaginea FRUIT EXTRACTS ON SERUM PARATHYROID HORMONE AND 1α,25-DIHYDROXYVITAMIN D
... The role of phyto-flavonoids in regulation of various hormones such as estrogens, androgens and thyroid is well reported (Narayana et al., 2001). This regulation in humans is performed by binding to 17 ...
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Influence of the Vitamin D binding Protein on the Serum Concentration of 1,25 Dihydroxyvitamin D3: SIGNIFICANCE OF THE FREE 1,25 DIHYDROXYVITAMIN D3 CONCENTRATION
... respectively; n = 58) increased during the intake of estro-progestogens (69±27 ng/liter and 488±90 mg/liter, respectively; n = 29), whereas the 25-OHD 3 concentration remained unchanged. A positive correlation was ...
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Vitamin D dependent rickets type II Defective induction of 25 hydroxyvitamin D3 24 hydroxylase by 1,25 dihydroxyvitamin D3 in cultured skin fibroblasts
... 1,25(OH)2D or vitamin D-dependent rickets type II (DD II). Fibroblasts were preincubated with varying concentrations of 1,25(OH)2D3 for 15 h and were then incubated with 0.5 microM [3H]25(OH)D3 at 37 ...
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Renal Hypophosphatemic Rickets: Growth Acceleration After Long-Term Treatment with 1,25-Dihydroxyvitamin-D3
... Treatment with 1,25-dihydroxyvitamin-D3 and phosphorus supplementation for as long as 48 months was evaluated in six patients with renal hypophospha-.. temic rickets.[r] ...
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Iron deficiency decreases renal 25-hydroxyvitamin D3-1α-hydroxylase activity and bone formation in rats
... -hydroxylase, 25-hydroxyvitamin D3-1 α -hydroxylase; ALP, alkaline phos- phatase; ANOVA, analysis of variance; BFR/BS, bone formation rate; BMC, bone mineral content; BMD, bone mineral density; BV/TV, bone ...
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The human vascular vitamin D hormonal system expression and regulation
... for 1α-OHase was optimised using commercially available Sheep Specific HRP-DAB Tissue Staining Kit (R&D Systems, Abingdon, ...minutes. 1α-OHase antibody 1:150 (The Binding Site, Birmingham, UK) in TBS-T ...
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