2-deoxy-2
![2-deoxy-2-[18]fluoro-D-glucose PET/CT (18FDG PET/CT) may not be a viable biomarker in Pompe disease](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
2-deoxy-2-[18]fluoro-D-glucose PET/CT (18FDG PET/CT) may not be a viable biomarker in Pompe disease
... investigated 2-deoxy-2-[18]fluoro-D-glucose (FDG) PET, a biomarker for glucose-metabolism, as a tool to evaluate disease activity and prognosis in ...
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Cholangiocarcinoma associated with limbic encephalitis and early cerebral abnormalities detected by 2 deoxy 2 [fluorine 18]fluoro d glucose integrated with computed tomography positron emission tomography: a case report
... by 2-deoxy-2-[fluorine-18]fluoro- D -glucose integrated with computed tomography-positron emis- sion tomography ( 18 F-FDG-PET/CT) was performed ac- cording to the following acquisition ...= 2 ...
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Positron emission tomography agent 2 deoxy 2 [18F]fluoro D glucose has a therapeutic potential in breast cancer
... Our imaging experiments in two different mouse mammary cancer models (the PyMT model of murine mammary cancer and the MMTV NeuT model, which carries the erbB-2 human breast cancer oncogenes) showed that it is ...
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Effects of 2'-deoxy-2'-azidocytidine on polyoma virus DNA replication: evidence for rolling circle-type mechanism.
... Moreover, after cleavage, Y-shaped molecules with three unequal arms were found, which could be explained as derived from the tail in rolling circle-type molecules starting from the norm[r] ...
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Standardised uptake values of 2 deoxy 2 [18F]fluoro d glucose using PET/CT in normal cats
... ABSTRACT: In this study we assessed the normal physiological and dynamic thoracoabdominal distribution of 18 F fluorodeoxyglucose 18F-FDG uptake and the standardized uptake values SUVs o[r] ...
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Assessment of 18F-FDG uptake in idiopathic pulmonary fibrosis: influence of lung density changes
... 18F-FDG: 2-deoxy-2-(18F)fluoro-D-glucose, or fluorodeoxyglucose; 6MWT: 6-min walking test; BAL: Bronchoalveolar lavage; DLCO: Diffusion capacity of the lungs for carbon monoxide (CO); FVC: Forced ...
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Synthesis, Conformation and Glycosidic Bond Stabilities of Septanoside Sugars
... In this context, bromo-oxepine III was examined using Pd-catalyzed C-C bond forming reactions, namely, Heck, Suzuki and Sonogashira reaction for the formation of hither-to unknown septanoside, branching out at ...
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Targeting adipose tissue
... type 2; EMA: European Medicines Agency; FAS: fatty acid synthase; FDG: 2- deoxy-2[ 18 F]fluoro-D-glucose; FFA: free fatty acids; Fndc5: fibronectin type III domain containing 5; GC: guanylate ...
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Assessment of the kidney function parameters split function, mean transit time, and outflow efficiency using dynamic FDG-PET/MRI in healthy subjects
... analog 2-deoxy-2-[ 18 F]fluoro-D-glucose (FDG), routinely used mainly for oncological positron emission tomography (PET), also participates in relevant renal ...
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Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents: 18F-FAU, 18F-FMAU, and 18F-FLT
... 1-(2’-deoxy-2’-fluoro-β-D-arabinofuranosyl) thymidine (FMAU) is another thymidine analogue that was origin- ally introduced as an anti-viral and anti-neoplastic com- pound, but was later abandoned ...
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Efficient triple helix formation by oligodeoxyribonucleotides containing alpha- or beta-2-amino-5-(2-deoxy-D-ribofuranosyl) pyridine residues.
... ribofuranosyl)pyridine (β-AP) is structurally analogous to dC but is considerably more basic, with a pK a of 5.93. We have synthesised 5′-psoralen linked oligodeoxy- ribonucleotides (ODNs) containing thymidine (dT) and ...
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Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer
... (RDS Eclips ST; Siemens) and an Explora FDG4 module (Siemens) in our center. All patients were required to fast for at least 6 h to ensure glucose blood levels below 10 mmol/L. Scanning was initiated 1 h after ...
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Metabolic liver function in humans measured by 2-18F-fluoro-2-deoxy-D-galactose PET/CT–reproducibility and clinical potential
... Measurements from the day-to-day study were tested for normality using the Shapiro-Wilk test and compared using Student’s paired t test or the signed Rank test as appropriate. Day-to-day variation and the impact of re- ...
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Plasminogen activator inhibitor 1 gene deficient mice I Generation by homologous recombination and characterization
... measured 2-4 h after endotoxin (2.0 mg/kg) injection were 63 +/- 2 ng/ml, 30 +/- 10 ng/ml, and undetectable (< 2 ng/ml) in PAI- 1+/+, heterozygous (PAI-1+/-) and PAI-1-/- mice, respectively (mean ...
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Higher baseline global leukocyte DNA methylation is associated with MTX non response in early RA patients
... We performed paired analysis to assess the change in global DNA (hydroxy)methylation over the first 3 months using paired-sample t tests. Associations between global DNA (hydroxy)methylation at baseline, at 3 months and ...
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Effect of dosimeter’s position on occupational radiation extremity dose measurement for nuclear medicine workers during 18F-FDG preparation for PET/CT
... According to the Council Directive Euratom of the EU [1], the ICRP, and the ICRU [2, 3], transposed into the French Labor Code [4], the limit of radiation (effective) dose to the whole body is 20 mSv over 12 ...
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Impaired glucose homeostasis in insulin like growth factor binding protein 1 transgenic mice
... The fasting blood glucose levels in transgenic and wild-type mice at various ages are shown in Fig. 1. Newborn and 1-wk-old mice were food-deprived for only 4 and 12 h, respectively, since they could not survive a ...
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Induction of Type C Virions from Normal Rat Kidney Cells by 2-Deoxy-d-Glucose
... To determine dose responses to 2-DG, NRK cells were grown for 20 h in MEM containing various concentrations of 2-DG, and culture fluids were assayed for reverse transcriptase activity.. [r] ...
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Positron Emission Tomography Imaging of Atherosclerosis
... tive remodeling. The artery eventually can expand no farther, and the plaque begins to occlude the lumen of the vessel causing circulatory obstruction [2-4] (Fig- ure 1). Unstable plaques that are prone to ...
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Detectability of Hypometabolic Regions in Mild Alzheimer Disease: Function of Time after the Injection of 2 [Fluorine 18] Fluoro 2 Deoxy d Glucose
... Before PET scanning, both patients and control subjects underwent MR imaging to confirm that they had no abnormal conditions. Detailed PET and MR imaging procedures are described elsewhere (2). Briefly, PET was ...
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