2-Deoxy-D-glucose
Original Article Protective effects of 2- deoxy-D-glucose on nephrotoxicity induced by cyclosporine A in rats
... of 2-deoxy-D-glucose on nephro- toxicity of cyclosporin A in ...of 2-DG on CsA-induced ...with 2-DG. Conclusions: 2-DG had obvious protective effect on nephrotoxicity ...
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Chronic Dietary Administration of 2 Deoxy D Glucose Does Not Compromise Neurobehavioral Functions at Tumor Preventive Doses in Mice
... and 2-deoxy-D-glucose (2-DG) have shown potential to produce tumor inhibitory and anti-aging effects ...exploring 2-DG as a potent anti-neoplastic agent [7] [10]. 2-DG is ...
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Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet
... circulating glucose levels coupled with an elevation of circulating ketone levels is thought to under- lie the therapeutic effects ...non-metabolizable glucose analogue 2- ...
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Increased Thirst and Plasma Arginine Vasopressin Levels during 2 Deoxy d glucose induced Glucoprivation in Humans
... of 2- deoxy-d-glucose (50 mg/kg), a competitive inhibitor of glucose utilization, or normal saline (sham), to 24 normal ...of 2-deoxy-d-glucose (2DG)-induced ...
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Anti-leucine rich glioma inactivated 1 protein and anti-N-methyl-D-aspartate receptor encephalitis show distinct patterns of brain glucose metabolism in 18F-fluoro-2-deoxy-d-glucose positron emission tomography
... to 2 years between symptom onset and diag- nosis), which had not been compared to a matched control group [24], suggesting that the anti-LGI1-induced brain metabolic pattern may depend on the disease course, time ...
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Incidentalomas of the prostate detected by 18 fluoro 2 deoxy D glucose positron emission tomography/computed tomography
... Introduction: Prostate incidentalomas are prostatic lesions suspicious for cancer discovered by imaging patients without a known history of prostatic cancer (CaP) for other reasons. ...
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Meta Analysis to Determine the Diagnostic Value of 2 18Fluoro 2 Deoxy D Glucose Positron Emission Tomography in Assessing Residual Tumors after Systemic Therapy for Metastatic Seminoma
... Abstract Background: A meta-analysis was performed to determine the value of 2-18fluoro-2-deoxy-D-glucose positron emission tomography FDG-PET for assessing viable tumor residuals after [r] ...
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THE EFFECT OF 2 DEOXY D GLUCOSE INFUSIONS ON LIPID AND CARBOHYDRATE METABOLISM IN MAN
... A REPRESENTATIVE PATTERN OF RESPONSE OF PLASMA FREE FATTY ACID AND GLUCOSE LEVELS FOLLOWING AN INFUSION OF 2-DEOXY-D-GLUCOSE... rise ranging from 1.5 Subject C.C.[r] ...
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Detectability of Hypometabolic Regions in Mild Alzheimer Disease: Function of Time after the Injection of 2 [Fluorine 18] Fluoro 2 Deoxy d Glucose
... We used Neurostat software (University of Michigan, Ann Arbor, MI) for anatomic standardization of PET images, as brain atrophy is sometimes seen in patients. In a previous study (4), we found that Neurostat was more ...
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2-Deoxy-D-glucose Mediates Dihydrodiol Dehydrogenases Over-expression and Cisplatin Resistance in Human Cervical Cancer Cells
... 1, 2, 5, 10, 20, 50µM) of cisplatin and incubated for 72 ...1.5, 2, 5, 10 µM) of cisplatin for 4 hours, cells were washed twice and added fresh medium and followed by two- week incubation to allow colony ...
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Combining 2-deoxy-D-glucose with fenofibrate leads to tumor cell death mediated by simultaneous induction of energy and ER stress
... stress, 2-Deoxy-glucose (2-DG) is particularly well-suited to take advantage of the therapeutic window that heightened stress in tumors ...with 2-DG leads to significant lowering of ATP ...
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Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer
... (RDS Eclips ST; Siemens) and an Explora FDG4 module (Siemens) in our center. All patients were required to fast for at least 6 h to ensure glucose blood levels below 10 mmol/L. Scanning was initiated 1 h after ...
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Biological and physical modifications of a murine oncornavirus by 2-deoxy-D-glucose.
... It has been suggested 9, 10 that high concentrations of 2-DG or D-glucosamine have little or no effects on cellular protein or RNA synthesis in chicken embryo fibroblasts as measured by [r] ...
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Effect of 2-deoxy-D-glucose on herpesvirus-induced inhibition of cellular DNA synthesis.
... ROTT Institut fur Virologie, Justus Liebig-Universitat, Giessen, Germany Received for publication 10 March 1975 In herpesvirus-infected cells which are kept in the presence of 2-deoxy-D-[r] ...
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Inhibition of the Multiplication of Vesicular Stomatitis and Newcastle Disease Virus by 2-Deoxy-d-Glucose
... Portions of 0.1 ml 1186 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The production of infectious vesicular stomatitis VSV and Newcastle disease virus can be complet[r] ...
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Inhibition of Herpes Virus-Induced Cell Fusion by Concanavalin A, Antisera, and 2-Deoxy-d-Glucose
... A An infected monolayer forming one total syncytium 10 h p.i.; Aa noninfected control cells treated with 20 gg of Con A per ml; B infected culture after incubation for 15 h with 20 Mg of[r] ...
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Induction of Type C Virions from Normal Rat Kidney Cells by 2-Deoxy-d-Glucose
... To determine dose responses to 2-DG, NRK cells were grown for 20 h in MEM containing various concentrations of 2-DG, and culture fluids were assayed for reverse transcriptase activity.. [r] ...
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Chronic expanding hematoma with a significantly high fluorodeoxyglucose uptake on 18F fluorodeoxyglucose positron emission tomography, mimicking a malignant soft tissue tumor: a case report
... F]fluoro-2 deoxy-D glucose positron emission tomog- raphy (FDG-PET) is an evolving diagnostic modality used for tumor detection, staging, therapeutic monitoring and follow-up evaluations for ...
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Increased FDG avidity in lymphoid tissue associated with response to combined immune checkpoint blockade
... fluoro-2-deoxy-D- glucose (FDG) uptake in benign lymphoid tissue, proved to be erroneous after assiduous review of radiographic imaging and correlative ...
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Behavior of FDG-avid supradiaphragmatic lymph nodes in PET/CT throughout primary therapy in advanced serous epithelial ovarian cancer: a prospective study
... Increasing evidence indicates that abnormal [ 18 F]-fluor- o-2-deoxy-D-glucose (FDG) accumulation in sdLNs is a common finding in advanced EOC [4–6]. International Federation of Gynecology and ...
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