2-Deoxy-D-Glucose (2-DG)
Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet
... non-metabolizable glucose analogue, 2-deoxy-D-glucose (2-DG), is a potent glycolytic inhibitor that can mimic effects of energy restriction both in vitro and in vivo, but ...
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Original Article Protective effects of 2- deoxy-D-glucose on nephrotoxicity induced by cyclosporine A in rats
... of 2-deoxy-D-glucose on nephro- toxicity of cyclosporin A in ...of 2-DG on CsA-induced ...with 2-DG. Conclusions: 2-DG had obvious protective effect ...
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Increased Thirst and Plasma Arginine Vasopressin Levels during 2 Deoxy d glucose induced Glucoprivation in Humans
... of 2- deoxy-d-glucose (50 mg/kg), a competitive inhibitor of glucose utilization, or normal saline (sham), to 24 normal ...of 2-deoxy-d-glucose (2DG)-induced ...
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Meta Analysis to Determine the Diagnostic Value of 2 18Fluoro 2 Deoxy D Glucose Positron Emission Tomography in Assessing Residual Tumors after Systemic Therapy for Metastatic Seminoma
... Abstract Background: A meta-analysis was performed to determine the value of 2-18fluoro-2-deoxy-D-glucose positron emission tomography FDG-PET for assessing viable tumor residuals after [r] ...
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Incidentalomas of the prostate detected by 18 fluoro 2 deoxy D glucose positron emission tomography/computed tomography
... Introduction: Prostate incidentalomas are prostatic lesions suspicious for cancer discovered by imaging patients without a known history of prostatic cancer (CaP) for other reasons. ...
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THE EFFECT OF 2 DEOXY D GLUCOSE INFUSIONS ON LIPID AND CARBOHYDRATE METABOLISM IN MAN
... A REPRESENTATIVE PATTERN OF RESPONSE OF PLASMA FREE FATTY ACID AND GLUCOSE LEVELS FOLLOWING AN INFUSION OF 2-DEOXY-D-GLUCOSE... rise ranging from 1.5 Subject C.C.[r] ...
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Induction of Type C Virions from Normal Rat Kidney Cells by 2-Deoxy-d-Glucose
... To determine dose responses to 2-DG, NRK cells were grown for 20 h in MEM containing various concentrations of 2-DG, and culture fluids were assayed for reverse transcriptase activity.. [r] ...
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Biological and physical modifications of a murine oncornavirus by 2-deoxy-D-glucose.
... It has been suggested 9, 10 that high concentrations of 2-DG or D-glucosamine have little or no effects on cellular protein or RNA synthesis in chicken embryo fibroblasts as measured by [r] ...
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Detectability of Hypometabolic Regions in Mild Alzheimer Disease: Function of Time after the Injection of 2 [Fluorine 18] Fluoro 2 Deoxy d Glucose
... We used Neurostat software (University of Michigan, Ann Arbor, MI) for anatomic standardization of PET images, as brain atrophy is sometimes seen in patients. In a previous study (4), we found that Neurostat was more ...
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Clinical value of fluorine-18 2-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography in penile cancer
... Squamous cell carcinoma of the penis is uncommon in developed countries, but its incidence in some developing countries is much higher [1, 2]. The scarcity of this disease has limited the conduct of prospective ...
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Inhibition of Herpes Virus-Induced Cell Fusion by Concanavalin A, Antisera, and 2-Deoxy-d-Glucose
... A An infected monolayer forming one total syncytium 10 h p.i.; Aa noninfected control cells treated with 20 gg of Con A per ml; B infected culture after incubation for 15 h with 20 Mg of[r] ...
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Effect of 2-deoxy-D-glucose on herpesvirus-induced inhibition of cellular DNA synthesis.
... ROTT Institut fur Virologie, Justus Liebig-Universitat, Giessen, Germany Received for publication 10 March 1975 In herpesvirus-infected cells which are kept in the presence of 2-deoxy-D-[r] ...
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Inhibition of the Multiplication of Vesicular Stomatitis and Newcastle Disease Virus by 2-Deoxy-d-Glucose
... Portions of 0.1 ml 1186 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The production of infectious vesicular stomatitis VSV and Newcastle disease virus can be complet[r] ...
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Chronic expanding hematoma with a significantly high fluorodeoxyglucose uptake on 18F fluorodeoxyglucose positron emission tomography, mimicking a malignant soft tissue tumor: a case report
... F]fluoro-2 deoxy-D glucose positron emission tomography images revealed increased uptake with a maximum standardized uptake value of ...on 2-[ 18 F]fluoro-2 deoxy-D ...
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Cholangiocarcinoma associated with limbic encephalitis and early cerebral abnormalities detected by 2 deoxy 2 [fluorine 18]fluoro d glucose integrated with computed tomography positron emission tomography: a case report
... researchers reported that VKGC antibodies identified by radioimmunoassay in which a complex of brain proteins (KV1.1 and KVI.2) are labeled does not necessarily indi- cate an absolute specificity for VGKC. The ...
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2-deoxy-2-[18]fluoro-D-glucose PET/CT (18FDG PET/CT) may not be a viable biomarker in Pompe disease
... FDG: 2-deoxy-2-[18]fluoro-D- glucose; FVC: Forced expiratory vital capacity; GAA : Acid α -glucosidase gene; Glc(4): Glcalpha1-6Glcalpha1-4glcalpha1-4Glc; GOT: Glutamat-Oxalacetet- ...
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Positron emission tomography agent 2 deoxy 2 [18F]fluoro D glucose has a therapeutic potential in breast cancer
... Our imaging experiments in two different mouse mammary cancer models (the PyMT model of murine mammary cancer and the MMTV NeuT model, which carries the erbB-2 human breast cancer oncogenes) showed that it is ...
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Standardised uptake values of 2 deoxy 2 [18F]fluoro d glucose using PET/CT in normal cats
... Up to now, most PET studies have implemented to- tal body scans. In the selected case, semi-quantitative analysis was implemented, and is based on the calcu- lation of SUVs. These SUVs have become a universal measurement ...
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An improved synthesis and preliminary biodistribution study of a Technetium-99m-labeled 2-amino-2-deoxy(thioacetyl)-D-glucose complex ([99mTc]-TA-DG) as a tumor imaging agent
... The biodistribution of the [ 99m Tc]-(TA-DG) complex was studied in normal mice (body mass 25–35 g) at 30 min and 1 h post-injection, according to a published procedure.. This complex s[r] ...
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Whole body metabolic tumor volume is a prognostic marker in patients with newly diagnosed stage 3B non-small cell lung cancer, confirmed with external validation
... In summary, among patients with Stage 3B NSCLC increasing MTVwb measured on baseline FDG PET/CT is associated with worse OS in both univariate and multivariate cox regression analysis, as seen in both the training and ...
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