2-pyrazoline
Synthesis, characterization and antimicrobial studies of novel 2- pyrazoline derivatives
... activity[1,2]. 2-Pyrazoline derivatives have also been reported in the literature to exhibit various pharmacological activities such as antimicrobial [3-8], anti-inflammatory [9] and antihypertensive ...
5
Synthesis, Antitubercular, Anticonvulsant and Antiinflammatory Activities of Some Novel 2-Pyrazoline Derivatives
... Inflammation of lungs is often related with the tuberculosis and convulsions are associated with the long term therapy of first line anti tubercular agents. Here in this present study an attempt has been made to ...
6
Synthesis, characterization and antibacterial evaluation of novel 2 pyrazoline derivatives
... Several 3-(β-picolinoylaminoazo methyl-5-aromatic substituted)-1-thioamide-2-pyrazoline derivatives (4a-4e) were synthesized by reacting substituted 1-(β-picolinoylaminoazo)-3- benzylidene ...
6
Synthesis, Characterization and Evaluation of Analgesic, Anti Inflammatory, Ulcerogenic Potential of Some 2 Pyrazoline Derivatives
... The discovery of cyclooxygenase-2, expressed in response to inflammatory stimuli, present in the central nervous system, not in the gastric mucosa has provided a unique opportunity in the development of NSAIDs ...
10
1 Acetyl 5 ferrocenyl 3 phenyl 2 pyrazoline
... between pyrazoline ring and the phenyl ring indicates that they are conjugated with each other; this is accord with the C1—C7 bond ...-2- pyrazoline (Kudar et ...
12
1 (N Ethylthiocarbamoyl) 3,5 di 2 furyl 2 pyrazoline
... 1,3-Di-2-furyl-2-propen-1-one (0.01 mol) was dissolved in ethanol (25 ml). Hydrazine hydrate (1 g, 0.02 mol) was then added. The solution was warmed in a water bath for 2 h. After cooling, the ...
7
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVOLUTION OF SOME NOVEL 2 PYRAZOLINE DERIVATIVES WITH CHALCONE
... including 2-pyrazolines which shows up variety of biological activities like anti-microbial [7] , anti-myco-bacterial [8] , anti- depressant [9] , anti-inflammatory [10] , analgesic [11] , anti-convulsant [12] , ...
18
MICROWAVE ASSISTED SYNTHESIS AND CHARACTERIZATION OF NEW 2-PYRAZOLINE DERIVATIVES
... of pyrazoline, it was planned to synthesise new pyrazoline derivatives using furan-2-carboxylicacid hydrazide and chalcones derived from acetophenone and substituted ...hydrazine. Pyrazoline ...
6
SYNTHESIS AND CHARACTERISATION OF 1,3,5 TRIPHENYL 2 PYRAZOLINE FOR ANTIMICROBIAL ACTIVITY
... Aim of the present work is to synthesize 1,3,5 triphenyl-2-pyrazoline. As the literature review reveals that benzalacetophenone is a bioactive lead molecule for synthesizing newer drug and have potent ...
15
SYNTHESIS, BIOLOGICAL EVALUATION AND MOLECULAR PROPERTIES PREDICTION OF 1, 3, 5 TRISUBSTITUTED 2 PYRAZOLINE DERIVATIVES
... trisubstituted 2-pyrazolines which are known for their biological importance like antimicrobial, anti-inflammatory, antitubercular, analgesic, anticancer, antimalarial, anti-viral, antihelmentic activities are ...
8
Synthesis and antimicrobial activity of novel 1 thiocarbamoyl 2 pyrazoline derivatives
... 1-Thiocarbamoyl-5-phenyl-3-[3 ’ -(4 ” -chlorophenyl)-2 ’ -thioxo-4 ’ (3 ’ H)-quinazolinon-1 ’ -yl]- 2-pyrazoline. 3b, brown solid, m.p. 100-02 ° C, yield 73.5%; IR (cm -1 ): 696.60 (C 5 -H), 1092.62 ...
5
1 Acetyl 5 (2 methoxyphenyl) 3 (2 methoxystyryl) 2 pyrazoline
... Pyrazolines and their derivatives display various biological properties, such as pesticidal, fungicidal, insecticidal, anti- in¯ammatory, anti-arthritic, antidepressant and antiviral activities, and have industrial ...
8
Synthesis and Spectral Characterization of Novel 2 Pyrazoline and Bis 2 Pyrazoline Containing Quinoline Moiety
... Numerous research programs have been devoted to the establishment of new synthetic methods and new heterocyclic combination because several biological active compounds contain a heterocyclic moiety as a fundamental ...
10
3 (4 Bromophenyl) 5 (4 chlorophenyl) 1 phenyl 2 pyrazoline
... C12 0.054 (3) 0.074 (3) 0.060 (3) −0.012 (3) 0.011 (2) −0.009 (3) C13 0.064 (3) 0.072 (3) 0.054 (3) −0.021 (3) 0.008 (2) 0.001 (2) C14 0.062 (3) 0.058 (3) 0.063 (3) −0.014 (2) −0.004 ...
6
5 (4 Chlorophenyl) 3 (4 nitrophenyl) 1 phenyl 2 pyrazoline
... Cl1 0.0847 (5) 0.0517 (4) 0.0809 (5) −0.0033 (3) 0.0313 (4) 0.0229 (4) O1 0.149 (2) 0.0683 (15) 0.121 (2) 0.0147 (15) 0.0827 (17) 0.0062 (14) O2 0.1079 (19) 0.163 (3) 0.0580 (14) 0.0525 (17) 0.0208 (13) ...
7
Synthesis and Antimicrobial Activity of 1 (4 aryl 2 thiazolyl) and 1 (4 aryl 2 oxazolyl) 3,5 diaryl 2 pyrazoline derivatives
... The presence of a strong electron withdrawing group at the para position of the phenacylbromide such as Br played an important role in the thiazole formation since it appears to increase its polar character and therefore ...
11
N Amidinio 3,5,5 trimethyl 2 pyrazoline 1 carboxamidine chloride (BPC 151), an oral hypoglycaemic agent
... Cl1 0.02040 (19) 0.0224 (2) 0.0232 (2) −0.00601 (13) 0.00061 (13) 0.00211 (13) N1 0.0165 (6) 0.0236 (6) 0.0158 (6) −0.0010 (5) 0.0043 (4) −0.0014 (5) N2 0.0152 (5) 0.0225 (6) 0.0144 (6) −0.0038 (4) 0.0038 ...
6
(SR) 5 (2,6 Dichlorophenyl) 3 (2 naphthyl) 1 phenyl 2 pyrazoline trichloromethane hemisolvate
... C17 0.045 (2) 0.055 (2) 0.0412 (17) −0.0041 (17) 0.0101 (15) 0.0053 (16) C18 0.057 (2) 0.043 (2) 0.057 (2) −0.0098 (17) 0.0152 (17) 0.0062 (16) C19 0.051 (2) 0.0459 (19) 0.054 ...
9
3,5 Dimethyl 1 (2 pyridylcarbonyl) 5 [(2 pyridylcarbonyl)hydrazino] 2 pyrazoline methanol hemisolvate
... 2-Picoloylhydrazine (0.548 g, 4 mmol) and ice acetic acid (0.48 g, 8 mmol) were added to a mixture of methanol/glycol (25 ml, 3:2), then 0.21 ml of acetylacetone (0.205 g, 2.05 mmol) was added and reacted ...
8
3 Phenyl 5 (2 thienyl) 2 pyrazoline 1 thioamide
... The bond lengths and angles of the thiocarbamoyl group are comparable with those of a related compound, O-(2-tert-butyl- 6-dimethylthiocarbamoyl-4-methylphenyl)N,N-diethylthio- carbamate (Castillo et al., 2003). ...
7