25-Dihydroxyvitamin D3
Renal Hypophosphatemic Rickets: Growth Acceleration After Long-Term Treatment with 1,25-Dihydroxyvitamin-D3
... Treatment with 1,25-dihydroxyvitamin-D3 and phosphorus supplementation for as long as 48 months was evaluated in six patients with renal hypophospha-.. temic rickets.[r] ...
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1,25 Dihydroxyvitamin D3 production by human keratinocytes Kinetics and regulation
... metabolize 25-hydroxyvitamin D3 to a number of metabolites, including 1,25-dihydroxyvitamin D3 ...for 25-hydroxyvitamin D3 of ...
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Ligation of TLR9 induced on human IL 10–secreting Tregs by 1α,25 dihydroxyvitamin D3 abrogates regulatory function
... however its functional relevance remains unclear. Here we have shown that TLR9 is highly expressed by human Treg secreting the antiinflammatory cytokine IL-10 induced following stimulation of blood and tissue CD3 + T ...
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Effects of I ,25-Dihydroxyvitamin-D3 on Renal Function, Mineral Balance, and Growth in Children with Severe Chronic Renal Failure
... 24,25-dihydroxyvitamin-D3 secretion, especially in relation to phosphorus,44’45 is being investigated by various laboratories.46’47 The role of hyperphospha- temia in suppressing serum c[r] ...
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1,25 Dihydroxyvitamin D3 upregulates the phosphatidylinositol signaling pathway in human keratinocytes by increasing phospholipase C levels
... 1,25-Dihydroxyvitamin D3 (1,25(OH)2D3) induces the differentiation of normal human keratinocytes, in part by increasing their basal intracellular calcium levels (Cai) over a period of ...
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1, 25 Dihydroxyvitamin D3 Protects the Heart Against Pressure Overload-induced Hypertrophy without Affecting SIRT1 mRNA Level
... 1, 25-dihydroxyvitamin D prevents increase of blood pressure in rats subjected to cardiac hypertrophy and reduces hypertrophy markers such as HW/BW as well as ANP and BNP mRNA levels which can directly be ...
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Enterohepatic physiology of 1,25 dihydroxyvitamin D3
... 1,25-dihydroxyvitamin D3 were excreted in bile was not saturable in the dose range tested ...1,25-dihydroxyvitamin D3 present in bile were found to be much more polar than ...
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Hyperresponsiveness of vitamin D receptor gene expression to 1,25 dihydroxyvitamin D3 A new characteristic of genetic hypercalciuric stone forming rats
... Abstract Hypercalciuria in genetic hypercalciuric stone–forming GHS rats is accompanied by intestinal Ca hyperabsorption with normal serum 1,25-dihydroxyvitamin D3 [1,25OH2D3] levels, el[r] ...
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Regulation of parathyroid hormone like peptide in cultured normal human keratinocytes Effect of growth factors and 1,25 dihydroxyvitamin D3 on gene expression and secretion
... We have examined the expression and secretion of endogenous parathyroid hormone-like peptide (PLP) in primary cultures of normal human keratinocytes. In response to growth factors and fetal bovine serum, PLP mRNA ...
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Inhibition of T lymphocyte mitogenesis by 1,25 dihydroxyvitamin D3 (calcitriol)
... 1,25-dihydroxyvitamin D3 (calcitriol), the most biologically active metabolite of vitamin D, upon phytohemagglutinin (PHA)-induced lymphocyte blast ...
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Ameloblasts and odontoblasts, target cells for 1,25 dihydroxyvitamin D3: a review
... Int I De, Bioi 39; 257 262 (1995) Ameloblasts and odontoblasts, target cells for 1,25 dihydroxyvitamin D3 a review ARIANE BERDAL', PETROS PAPAGERAKIS, DOMINIQUE HaTTON, ISABELLE BAILLEUL FORESTIER, JE[.] ...
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Decreased 1,25 dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients
... 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) in uremic hyperparathyroidism is thought to be caused, in part, by a 1,25(OH)2D3 receptor (VDR) deficiency in the ...
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The Influence of 1α.25-Dihydroxyvitamin D3 Coating on Implant Osseointegration in the Rabbit Tibia
... Vitamin D has been shown to play an essential role in bone mineral homeostasis and in its active form, 1α,25-dihydroxyvitamin D3 [1.25-(OH) 2 D 3 ], may act as a bioactive protein promoting new bone ...
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Evidence that 1,25 dihydroxyvitamin D3 inhibits the hepatic production of 25 hydroxyvitamin D in man
... of 25-hydroxyvitamin D ...1,25-dihydroxyvitamin D3 [1,25(OH)2D3] would alter the response of serum 25-OHD to challenge with vitamin ...serum 25-OHD, from ...serum 25-OHD in ...
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Granulocyte macrophage colony stimulating factor Sensitive and receptor mediated regulation by 1,25 dihydroxyvitamin D3 in normal human peripheral blood lymphocytes
... 1,25-dihydroxyvitamin D3 (1,25[OH]2D3), the most hormonally active metabolite of vitamin D3, modulates sensitively and specifically both the protein and messenger RNA accumulation of the multilineage ...
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Effects of 1,25-dihydroxyvitamin D3 on pathological changes in rats with diabetic cardiomyopathy
... Background: The role of 1,25-dihydroxyvitamin D3 (vitamin D) in the apoptosis of diabetic cardiomyopathy (DCM) is unclear. This study is to investigate the effects of vitamin D on the pathological changes ...
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Effect of age on the conversion of 25 hydroxyvitamin D3 to 1,25 dihydroxyvitamin D3 by kidney of rat
... of 25-hydroxyvitamin D3 with significantly increased intestinal absorption of calcium and a three-fold increase in the intestinal content of vitamin D-stimulated calcium-binding ...of ...
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Influence of the Vitamin D binding Protein on the Serum Concentration of 1,25 Dihydroxyvitamin D3: SIGNIFICANCE OF THE FREE 1,25 DIHYDROXYVITAMIN D3 CONCENTRATION
... respectively; n = 58) increased during the intake of estro-progestogens (69±27 ng/liter and 488±90 mg/liter, respectively; n = 29), whereas the 25-OHD 3 concentration remained unchanged. A positive correlation was ...
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1 alpha,25 dihydroxyvitamin D3 suppresses proliferation and immunoglobulin production by normal human peripheral blood mononuclear cells
... determined by enzyme-linked immunosorbent assay, was similarly inhibited by increasing concentrations of 1,25-(OH)2-D3. Half-maximal inhibition of DNA and Ig synthesis was found at 10(-10) to 10(-9) M ...
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1,25 Dihydroxyvitamin D3 is a negative endocrine regulator of the renin angiotensin system
... Inappropriate activation of the renin-angiotensin system, which plays a central role in the regulation of blood pressure, electrolyte, and volume homeostasis, may represent a major risk factor for hyper- tension, heart ...
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