3′-UTRs
ADAR1-mediated RNA-editing of 3′UTRs in breast cancer
... and 3 ′ UTR regions [4, 19, 20], Similarly, we found a large number of edited sites at those regions ...= 3) was 3501 and for BC cells (n = 78) was 4053 A to G(I) sites, not finding significant differences ...
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Developmental RNA processing of 3′UTRs in Hox mRNAs as a context dependent mechanism modulating visibility to microRNAs
... Ubx 3 ⬘ UTR sequences, which produces transcripts with variable numbers of miRNA target sites at different temporal and spatial coordinates during development; ...different 3 ⬘ UTRs in different ...
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Comprehensive Mapping and Analysis of Kaposi's Sarcoma-Associated Herpesvirus 3′ UTRs Identify Differential Posttranscriptional Control of Gene Expression in Lytic versus Latent Infection
... their 3= ...factor 3 (v-IRF3), v-IRF2, ORF 40, K14, and the ORF 58 to ORF 61 cluster ...KSHV 3= UTRs use less common polyadenylation sequences to terminate transcription, such as AUUAAA (for ...
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Detection of canonical A-to-G editing events at 3’ UTRs and microRNA target sites in human lungs using next-generation sequencing
... their 3’ ...the 3’ UTR were reported to alter the miRNA target ...the 3’ UTR, site-specific RNA editing can alter miRNA binding sites thus affecting gene expression ...
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Double-strand break repair and colorectal cancer: gene variants within 3 UTRs and microRNAs binding as modulators of cancer risk and clinical outcome
... miRNAs typically mediate fine regulation of gene expression, tuning rather than altering protein levels [37]. There is evidence that miRNAs can control DNA damage response by interacting with DNA repair genes. Most of ...
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Histone mRNA translation in metazoans : SLIP1 as the bridging factor between the 5' and 3' UTRs of the histone mRNA
... Histone proteins packages newly synthesized DNA into higher organizations. During DNA synthesis in metazoans, there is a high demand for biosynthesis of histone proteins. Strict regulation of histone protein expression ...
192
A translational block to HSPG synthesis permits BMP signaling in the early Drosophila embryo
... and 3 ⬘ UTRs are sufficient to confer regulation on the heterologous GFP ...through 3 ⬘ UTRs, as both 5 ⬘ and 3 ⬘ ttv sequences are necessary to inhibit ...⬘ UTRs of ...
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Tissue and development specific induction and turnover of hsp70 transcripts from loci 87A and 87C after heat shock and during recovery in Drosophila melanogaster
... the 3′UTRs on hsp70 ...two 3′UTR riboprobes hybridized only to a subset of cells that were always in characteristically organized ...the 3′UTRs, other cells quickly removed ...the ...
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Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia
... WGCNA identified 21 co-expression modules with sizes ranging from 41 to 181 transcripts from the ex- pression data and 17 co-differential methylation modules with sizes ranging from 37 to 284 transcripts from the ...
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Gene characterisation, isoforms and recombinant expression of carcinin, an antibacterial protein from the shore crab, Carcinus maenas
... and 3’ UTRs (lower case text), the non-synonymous nucleotide changes leading to isoforms identified in the current study (lower case bold text) or synonymous (lower case italic text), the stop codon (*), ...
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Control of Translation by the 5′- and 3′-Terminal Regions of the Dengue Virus Genome
... The viral sequences present in DCLD and WCLW RNAs included part of the capsid coding region in addition to the 5 ⬘ and 3 ⬘ UTRs. The capsid coding regions were included be- cause they contain the conserved ...
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Extensive identification and analysis of conserved small ORFs in animals
... clear 3 nt periodicity in ribosomal fragments, which is not always easily achievable (for example, due to species-specific ribosome conform- ational properties [11, ...in 3′UTRs reach mar- ginal ...
21
Differential genome-wide profiling of alternative polyadenylation sites in nasopharyngeal carcinoma by high-throughput sequencing
... Furthermore, 3 ’ UTRs harbor several cis-elements, such as U-rich elements (USE), poly A signals (PAS), ARE (AU-rich elements), cytoplasmic polyadenylation elements, miRNA target sites and other unknown ...
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Stiff matrix instigates type I collagen biogenesis by mammalian cleavage factor I complex-mediated alternative polyadenylation
... the 3¢ UTR cleavage and polyadenylation represents a common characteristic among many disease states, including lung ...the 3¢ UTRs of type I collagen (COL1A1) and fibronectin (FN1) in primary human ...
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STARD13-correlated ceRNA network-directed inhibition on YAP/TAZ activity suppresses stemness of breast cancer via co-regulating Hippo and Rho-GTPase/F-actin signaling
... network. Firstly, we analyzed the transcriptome of MDA-MB-231 cells with STARD13-3′UTR stable ex- pression or not based on RNA sequencing data. Hippo signaling was shown on the top of the most upregulated pathways ...
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Transcriptome wide effects of inverted SINEs on gene expression and their impact on RNA polymerase II activity
... different 3′ UTRs each harboring two Alu elements in inverted ...the 3′ UTR of the Nicolin (Nicn1) gene, which had already been proven to interfere with gene expression when fused to a green ...
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Implication of the miR-184 and miR-204 Competitive RNA Network in Control of Mouse Secondary Cataract
... the 3′UTRs of potential SC target mRNAs; for example, miR-184 targets the cataract-associated GTPase binding pro- tein bridging integrator 3 [Bin3], and miR-204 targets the homeobox transcrip- tion ...
11
Role of the 3′-Untranslated Regions of Alfalfa Mosaic Virus RNAs in the Formation of a Transiently Expressed Replicase in Plants and in the Assembly of Virions
... the 3 ⴕ -UTR of AMV in assembly of an active RdRp ...the 3⬘-UTRs of RNAs 1 and 2 were both deleted, in leaves infiltrated with R1⌬/2⌬, P1 and P2 appeared to be present in a complex with similar ...
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Mutations in coat protein binding sites of alfalfa mosaic virus RNA 3 affect subgenomic RNA 4 accumulation and encapsidation of viral RNAs.
... The 3 * -untranslated regions (3 * -UTRs) of the three RNAs of alfalfa mosaic virus (AMV) contain a specific binding site for coat protein (CP) and act as a promoter for minus-strand RNA synthesis by ...
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Japanese Macaque Rhadinovirus Encodes a Viral MicroRNA Mimic of the miR-17 Family
... (IRF9) 3= UTR directly, and when overexpressed in epithelial cells, it can promote herpes simplex virus 1 replication (38, 42, 55, ...target 3= UTRs harboring miR-17-5p or miR-20a binding sites, ...
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