5-ht2a
Association between 5 HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach
... allele distributions in patient subgroups compared with controls may indicate some part of the genetic susceptibil- ity to schizophrenia, which has been linked to abnormal stress response, and even more importantly ...
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Reiter, Antje (2012): Genetische Variationen im 5-HT2A Gen im Zusammenhang mit suizidalem Verhalten. Dissertation, LMU München: Medizinische Fakultät
... Es handelt sich sowohl bei dem Polymorphismus rs643627, wo ein Austausch der Basen Adenin und Guanin stattfindet, als auch bei dem Polymorphismus rs594242, bei dem es sich um einen Austausch von Cytosin gegen Guanin ...
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5-HT2A Receptor Binding and Antidepressant Studies on Anximin, a Polyherbal Formulation
... 382 5. 5-HT2A receptor binding assay: All the animals were sacrificed by means of quick decapitation after 1 hr of last drug ...of 5 mM Tris buffer (pH ...
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Gerngroß, Christine (2009): Gedächtnisleistungen in Assoziation mit Polymorphismen des 5-HT2A- Rezeptorgens. Dissertation, LMU München: Medizinische Fakultät
... des 5-HT2A- Rezeptorgens, der mit dem stillen T102C- Polymorphismus im Kopplungsungleichgewicht steht, und zwar den A-1438G- Polymorphismus (rs6311), der sich nahe an der Promoterregion des Gens befindet ...
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Assessment of Changes in Expression of the 5-HT2A and GABAA Receptor Genes in Peripheral Blood Mononuclear Cells of Gas Station Workers, Tehran, Iran
... 30. Thetkathuek, A., Jaidee, W., Saowakhontha, S., Ekburanawat, W., Neuropsychological symptoms among workers exposed to toluene and xylene in two paint manufacturing factories in eastern Thailand. Adv Prev Med, 2015, ...
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Bampalis, Vasileios (2016): Role of the serotonin transporter and the 5-HT2A and 5-HT4 receptors for platelet function in blood. Dissertation, LMU München: Medizinische Fakultät
... platelet 5-HT2A receptors might be a good target for future anti-platelet ...of 5-HT2A antagonists on platelet function in human blood in vitro under static and arterial flow conditions, after ...
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ERβ and ApoE isoforms interact to regulate BDNF–5-HT2A signaling and synaptic function in the female brain
... Depression manifests in up to 50% of patients with Alzheimer’s disease (AD) [1–3] and is associated with in- creased neurological impairment [4] and mortality [5]. In addition, depression is an independent risk ...
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The Serotonin 5-HT2A Receptor Antagonist Ritanserin Induces Apoptosis in Human Colorectal Cancer and Acts in Synergy with Curcumin
... Tissue sections (3 µm) from paraffin blocks were deparaffinized and hydrated. For antigen retrieval, sections were incubated with citrate buffer (10 mM, pH 6.0), heated twice in microwave at 750 w for 5 min. After ...
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A polymorphism in the human serotonin 5 HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation
... ings modestly prone to false positive results. The significance of our results can also be gauged considering the FPRP val- ues we obtained under different scenarios (Table 3). Whilst no significant FPRP values were ...
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5 HT2A Receptor Activation Normalizes Exaggerated Fear Behavior in p Chlorophenylalanine (PCPA) Treated Rats
... Thirty-three male Sprague-Dawley rats (Harlan, Houston, TX) weighing approximately 175 - 200 g at time of ex- perimentation were used. Rats were individually-housed upon arrival and maintained on a 12-h light/dark cycle ...
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5-HT2A Receptor: A Newer Target for Obesity
... Obesity is a medical condition in which excess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems 1. Diet-induced ...
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QSAR STUDY ON BENZODIFURAN ANALOGS AS POTENT 5 HT2A RECEPTOR AGONISTS WITH OCULAR HYPOTENSIVE ACTIVITY
... and 5-HT receptors in relevant ocular tissues like the iris- ciliary body [3,4] hinted out that serotonin may be helpful in controlling ...that 5-HT 2 receptor agonists are effective in lowering IOP in the ...
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Human biodistribution and radiation dosimetry of the 5-HT2A receptor agonist Cimbi-36 labeled with carbon-11 in two positions
... carbon-11), thus assuming simple physical decay. These values were subsequently normalized by divid- ing by injected activity and then multiplied by stand- ard organ masses of the OLINDA male or female adult phantom ...
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5-HT2A Serotonin Receptor Density in Adult Male Rats’ Hippocampus after Morphine-based Conditioned Place Preference
... crease 5-HT levels in the brain (Tao & Auerbach, ...neurotransmitter 5-HT plays an important role in the regulation of reward-related ...instance, 5-HT is involved in natural reward-related ...
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IL-1β induces murine airway 5-HT2A receptor hyperresponsiveness via a non-transcriptional MAPK-dependent mechanism
... conditions, 5-HT has been reported to show some effects in respiratory tissues by activation of different subtype ...that 5-HT 2A receptor activation causes air- way contraction in-vivo and in-vitro, and ...
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Schertl, Stefan (2012): Assoziationsuntersuchung von Polymorphismen im 5-HT2A-Rezeptor-Gen mit Aspekten präfrontaler Kognition und Schizophrenie. Dissertation, LMU München: Medizinische Fakultät
... Abdolmaleky et al. (2004) nahmen eine Meta-Analyse von 31 Fall-Kontroll- Assoziationsstudien des Markers T102C, die sich insgesamt aus 4632 Patienten und 4410 Kontrollprobanden zusammensetzen, vor. Sie fanden eine ...
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Modulating the rate and rhythmicity of perceptual rivalry alternations with the mixed 5-HT2A and 5-HT1A agonist psilocybin
... Specifically, the oscillator model proposes that a number of brainstem nuclei encompassing regions such as the raphe nuclei, the ventral tegmental area, and the locus coeruleus are responsible for the generation of these ...
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Role of N-Linked Glycosylation of the 5-HT2A Receptor in JC Virus Infection
... washed with PBS at 24 h following transfection or tunicamycin treatment and fixed in cold MeOH at ⫺20°C for ⬎10 min. Cells were then washed, permeab- ilized using 1% Triton X-100 at RT for 5 min, and blocked in ...
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Is there an association between 5 ht receptor (5 ht2a) gene promoter polymorphism and obesity?
... lower intakes than did G allele carries without significant relation to maturation indexes as weight, height and body mass index.This is in consistence with Aubert et al., 2000 who found that the lower energy intake in ...
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<p>Neuroprotection by 2,3,5,4ʹ-tetrahydroxystilbene-2-O-β-D-glucoside extracts from <em>Polygonum multiflorum</em> against cerebral ischemia/reperfusion injury through the 5-hydroxytryptamine/5-hydroxytryptamine receptor pathway</p>
... of 5-hydroxy- tryptamine (5-HT) and other neurotransmitters in the ...1 5-HT transporter (5-HTT) is a transporter with the highest af fi nity for 5-HT and is widely present in the limbic ...
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