α-Aminophosphonates
A facile and efficient One pot Three Component Reaction (Kabachinik Fields Reaction) for the Synthesis of Novel α Aminophosphonates by 1, 4 Dimethylpiperazine as a new catalyst
... The α -aminophosphonate moiety is a versatile and novel pharmacaphore due to broad spectrum of biological activity exhibited by compounds bearing this structural ...for α -aminophosphonates has ...
8
“Synthesis and Antimicrobial Activity of Novel α-Aminophosphonates Bearing Pyrazoloquinoxaline Moiety” by Mohamed A. Hamed, Ahmed A. El Gokha, Alaa Fathy A. Ahmed, Mohamed Sabry Abd Elraheam Elsayed, R. Tarabee, Ahmed El S. Abdel Megeed, Ibrahim El-Tantawy El Sayed, Egypt.
... The acylimine intermediate III is attacked by nucleophilicphosphite with the formation of a phosphonium intermediate IV and that both reactions are catalyzed by the Lewis acid. Reaction of phosphonium intermediate IV ...
9
Sulfated zirconia: A novel and reusable catalyst for the one pot synthesis of α aminophosphonates
... In conclusion, we have shown that sulfated zirconia catalyzes efficiently the one-pot synthesis of biologically active α-aminophosphonates in good yields via a three-component coupling reaction of an ...
6
SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL α AMINOPHOSPHONATES BEARING A QUINOLINE MOIETY
... Antibacterial Screening: The diverse biological activities of aminophenylaminoquinoline derivatives and their α-aminophosphonates prompted us to test and study the antibacterial activities of some of the ...
9
Efficient Synthesis of β-Lactam-Containing α-Aminophosphonates Using Fumaric Acid as Mild Catalyst
... novel α- aminophosphonate esters containing β-lactam moiety is ...of α-aminophosphonate esters by reacting N-(4- methoxyphenyl)-2-(substituted) propiolactam-3-carbaldehyde with amine and triethylphosphite ...
8
Synthesis and Antibacterial Activity of Novel Cyclic α-Aminophsophonates
... occurring α-amino acids II (cf. Figure 1). The biological activity of α –aminophosphonates was reported in literatures as anticancer [3,4] and antibacterial ...Therefore, α ...
6
Synthesis of New A-Aminophosphonates by One Pot Reaction using Tetramethyl Guanidine (TMG)-as A Catalyst
... The schiff’s bases were prepared by reacting vaniline (4-hydroxy-3-methoxy benzaldehyde) with substituted aromatic amines in refluxing toluene. Dialkyl / diaryl phosphite undergoes addition readily with aromatic Schiff’s ...
8
Synthesis of and characterization of a aminophosphonates of fluorinated pyrazole imines using triethyl phosphite and TMSCl
... Under these conventional conditions, the formation of the target compounds was observed in poor to moderate yields (35-74%) indicating the limitations of conventional processes. To overcome the drawbacks of such ...
6
catalyzed -aminophosphonates and phosphonated N-(substituted phenyl) sulfonamides of 2-aminothiophene: Synthesis and biological evaluation
... new α -aminophosphonates of2-aminothiophene in high yields through one-pot three component reaction (Kabachnik-Fields reaction) catalyzed by silica supported ZnCl 2 under solvent-free conditions and the ...
14
“Synthesis and Antimicrobial Activity of Novel mono- and bis-a-Aminophosphonate Derivatives” by Ahmed A. El Gokha, Abdullah Ahmed S. Ahmed, Nayera A.M. Abdelwahed, Ibrahim El-Tantawy El Sayed, Egypt.
... bis- α-aminophosphonates 8 and 9 were based on the molar ratio of carbonyl compounds, aniline and ...of α-aminophosphonates using LiClO 4 as a ...
5
-
... X-ray diffraction measurements were performed on Co α Pt 1- α /Pd, Co/Pd, Co/Fe, and Co/W multilayer samples with different structures, such as Co α Pt 1- α alloy layer composition α,[r] ...
9
Mini review on initiatives to interfere with the propagation and clearance of alpha synuclein in Parkinson’s disease
... Although α-syn oligomers are thought to be the toxic species, it is the abnormal aggregation of α-syn into fi- brils that underpins the characteristic LP seen micro- ...that α-syn can form small ...
5
Increased Virulence and Competitive Advantage of a/α Over a/a or α/α Offspring Conserves the Mating System of Candida albicans
... When equal numbers of an engineered a / a /␣2 strain and its isogenic a / a parent strain were co- injected, the a / a /␣2 strain exhibited a competitive advantage at the time of host mo[r] ...
8
On Quasi Intuitionistic -Open Maps
... (ii) ⇒ (iii) Assume (ii) holds. Let x ~ ∈ X and U be an arbitrary intuitionistic α- neighbourhood of x ~ ∈ X. Then there exists an intuitionistic α-open set V in X such that x ~ ∈ V ⊂ U . Then by (ii) f (V ...
5
Octa O acetyl α,α trehalose ethanol disolvate
... The unit-cell volume is 0.4% smaller for the ethanol disolvate; this may be attributed both to the lower temperature of the present study 110 K in comparison with 150 K used in the study[r] ...
13
Diphenyl 2 (α,α,4 trichlorobenzyl)phenyl phosphate
... Data collection: APEX2 Bruker, 2003; cell re®nement: APEX2; data reduction: SAINT-Plus Bruker, 2003; programs used to solve structure: SHELXS97 Sheldrick, 1997; programs used to re®ne st[r] ...
7
PubMedCentral-PMC5253318.pdf
... The present study is intended as an exploratory analysis of variation in serum levels of 3 α , 5 α -THP and 3 α ,5 α -THDOC, as well as of the neuroactive steroid precursor pregnenolone,[r] ...
37
Operation on Fine Topology
... an α operation approaches on a class τ of sets and studied the concept of α-continuous functions with α-closed graphs and α-compact ...of α-closure of a set in X via α-operation ...
18
Novel endocrine therapeutic strategy in endometrial carcinoma targeting estrogen-related receptor α by XCT790 and siRNA
... ERR α sense 5 ′ -ACC GAG AGA TTG TGG TCA CCA-3 ′ , anti-sense 5 ′ -CAT CCA CAC GCT CTG CAG TACT-3 ′ (101 bp); glyceraldehyde 3-phos- phate dehydrogenase (GADPH, control) sense 5 ′ -GCA CCG TCA AGG CTG AGA AC-3 ′ , ...
15
Utilization of α Keto and α Hydroxy Analogues of Valine by the Growing Rat
... Since food intake rats eating valine-free diets containing 0, 35, or 70 and weight gain are both dependent on valine content ,.mol/g diet a-ketoisovaleric acid were injected with 1-2 of [r] ...
8