acetyl-CoA
Materials and methods for the alteration of enzyme and acetyl CoA levels in plants
... of acetyl CoA synthetase (ACS), plastidic pyruvate dehydrogenase (pPDH), ATP citrate lyase (ACL),Arabidopsis pyruvate decarboxylase (PDC), and Arabidopsis aldehyde dehydrogenase (ALDH), specifically ALDH-2 ...
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Identification and cytochemical immunolocalization of acetyl-CoA acetyltransferase involved in the terpenoid mevalonate pathway in Euphorbia helioscopia laticifers
... The acetyl-CoA acetyltransferase (AACT), or named acetoacetyl-CoA thiolase (ACAT) is a kind of enzyme that catalyzes hydrolysis and ...two acetyl CoA to produce acetyl ...
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Application of reverse phase HPLC to quantify oligopeptide acetylation eliminates interference from unspecific acetyl CoA hydrolysis
... detecting CoA and acetyl CoA in the same run, showed the same tendencies as the Abs 215 nm signals (Figure 3A and ...of acetyl CoA (Figure 3A, peak annotated 'b') and an additional peak ...
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Engineering of acetyl-CoA metabolism for the improved production of polyhydroxybutyrate in Saccharomyces cerevisiae
... the acetyl-CoA/CoA ratio, the total acetyl-CoA plus CoA concentration and pH (van Wegen et ...from acetyl- CoA occurs (Bohmert et ...
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ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae
... shuttling acetyl- CoA from the mitochondrion to the cytoplasm does not exist in ...shuttle acetyl- CoA through the intermediate ...cytoplasmic acetyl-CoA derived ...
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Quantitative analysis of acetyl-CoA production in hypoxic cancer cells reveals substantial contribution from acetate
... In addition to increased serum fatty acid scavenging, we observed a large fraction of fatty acid carbon (20%–50% depending on the cell line) in hypoxic cells not coming from either glucose or glutamine. Here, we used 13 ...
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Wild oat (Avena fatua L ) biotypes resistant to acetolactate synthase and acetyl CoA carboxylase inhibitors in Poland
... occurrence of wild oat biotypes resistant to her- bicides is complicated by the fact of occurrence of several botanical varieties of wild oat differing in sensitivity to used herbicides. Therefore it is a clear signal ...
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Linking Acetyl-Coa Metabolism and Histone Acetylation to Dynamic Gene Regulation in Yeast and Mouse Hippocampus
... local acetyl-CoA concentration by recycling CoA and acetate derived from enzymatic activity of HATs and HDACs, ...for acetyl coenzyme A synthesis 174 ...
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Improving acetyl-CoA biosynthesis in Saccharomyces cerevisiae via the overexpression of pantothenate kinase and PDH bypass
... improving acetyl-CoA level in ...of acetyl-CoA, but to the best of our knowledge, there have been no reports on engineering the “-CoA” part so ...for CoA synthesis, which ...
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Acetyl CoA carboxylase in photosynthetic tissue : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University
... on acetyl-CoA c a rboxyl a s e activity ...of acetyl -CoA c arboxyl as e decrea sed with the age of the etio l ated t i s sue and with increa s ing t ime of il lumina t ion of etiol ated s ...
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Acetyl CoA carboxylase in the photosynthetic tissue of maize :a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in biochemistry at Massey University
... The changes in the level of acetyl-CoA carboxylase activity paralleled changes in fatty acid levels in tissue along the length of the 9-day-old maize leaf... The levels of both.[r] ...
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Mevalonate production from ethanol by direct conversion through acetyl-CoA using recombinant Pseudomonas putida, a novel biocatalyst for terpenoid production
... The acetyl-CoA generated from ethanol catabolism is directly introduced into the heterologous mevalonate pathway for the synthesis of mevalonate, a precursor of terpenoid (acetyl-CoA to ...
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Characterizing the effect of expression of an acetyl-CoA synthetase insensitive to acetylation on co-utilization of glucose and acetate in batch and continuous cultures of E. coli W
... an acetyl-CoA synthetase insensitive to acety- lation (acs_L641P) from a constitutive promoter would have a similar effect, enabling efficient co-utilization of glucose and acetate at high ...insensitive ...
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Reversal of diet induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl CoA carboxylases 1 and 2
... Hepatic steatosis is a core feature of the metabolic syndrome and type 2 diabetes and leads to hepatic insulin resistance. Malonyl-CoA, generated by acetyl-CoA carboxylases 1 and 2 (Acc1 and Acc2), ...
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Effect of food deprivation and hormones of glucose homeostasis on the acetyl CoA carboxylase activity in mouse brain: a potential role of acc in the regulation of energy balance
... brain acetyl CoA carboxylase (ACC) activity during food deprivation and under the influence of hormones of glucose homeostasis: glucagon and ...malonyl CoA levels, and subsequent modulation of NPY ...
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Engineering cytoplasmic acetyl-CoA synthesis decouples lipid production from nitrogen starvation in the oleaginous yeast Rhodosporidium azoricum
... for acetyl-CoA (AcCoA) formation in Rhodosporidium azoricum by overexpressing genes encoding for homologous phosphoketolase (Xfpk) and heterologous phospho- transacetylase ...
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Microalgal lipid biosynthesis: phylogeny of acetyl-CoA carboxylase and gene expression patterns of key enzymes
... Chromalveolata, which share a common ancestor with the Haptophytes, Stramenopiles and Alveolata, but do not contain a plastid, avoiding assumptions of multiple plastid losses (Bodył et al., 2009). Overall, algal ...
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Cytosolic acetyl-CoA promotes histone H3 lysine 27 acetylation in Arabidopsis
... cytosolic acetyl-CoA in mammalian, yeast, and Drosophila cells (Takahashi et ...cytosolic acetyl-CoA in yeast cause hyperacetylation at multiple lysine residues of histone H3 and H4 and there ...
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Phylogenetic analysis of nucleus-encoded acetyl-CoA carboxylases targeted at the cytosol and plastid of algae
... pathways. Acetyl-CoA carboxylase (ACCase) is a key enzyme in the fatty acid synthesis and elongation pathways in algae, where ACCase exists in two loca- tions (cytosol and plastid) and in two forms ...
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Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production
... We used flux balance analysis (FBA) to predict the effect of phosphoketolase reactions on n-butanol produc- tion in Synechocystis PCC 6803. We added the n-butanol reactions and the two Xfpk reactions to a genome scale ...
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