Acridine derivatives
Pharmacophore Modeling and 3D-QSAR Study of Acridine Derivatives for the Development of Better Antileishmanial Agents
... Abstract: Several experimental works have been performed to prove the effectiveness of acridine derivatives against Leishmania. A diverse set of 60 compounds with IC50 inhibition data was collected from ...
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Synthesis and cytotoxic activity of acridine derivatives substituted with benzimidazole, benzoxazole and benzothiazole
... Acridine derivatives were primarily used as stains for dye manufacturing ...e.g., acridine orange ...the acridine nucleus were available ...The acridine derivatives known as ...
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SYNTHESIS, CHARACTERIZATION AND ANTIOXIDANT ACTIVITY OF NOVEL 9 (PIPERAZIN 1 YL) ACRIDINE DERIVATIVES
... 9-(piperazin-1-yl) acridine derivatives were synthesized by [(4-Methyl-2-nitrophenyl) amino] benzoic acid, phosphorus oxychloride, piperazine, dichloro methane evaluated for their antioxidant activity by ...
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Synthesis of some novel heterocyclic azo dyes for acridine derivatives and evaluation of their antibacterial activities
... for acridine derivatives were synthesized using different approaches depending on the position of functional ...unsubstituted acridine that was converted by nitration and amination to compounds that ...
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SYNTHESIS OF SOME NOVEL HETEROCYCLIC AZO DYES FOR ACRIDINE DERIVATIVES AND EVALUATION OF THEIR ANTIBACTERIAL ACTIVITIES
... The Main focus of this research work was to synthesize, characterize and evaluate antimicrobial activities of the newly synthesized Chalcone derivatives, structures of synthesized compounds were confirmed and ...
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Cu (II) Catalyzed Gateways In The Synthesis of Acridine Derivatives and Their Biological Evaluation as Anti-Cancer Drugs
... perylene derivatives have been widely studied in medicinal chemistry because they can be considered potential antitumor drugs acting as telomerase inhibitors 47 ...
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One pot multicomponent synthesis and antibacterial evaluation of some novel acridine derivatives
... novel acridine derivative by the one-pot condensation of 3, 4, 9, 10- tetrahydroacridine-1(2H)-one, substituted aldehyde and liquior ammonia in alkaline polyethylene glycol (PEG-400) as green reaction ...
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Theoretical investigation on the optoelectronic properties of low band gap acridine and carbazole derivatives for photovoltaic devices
... Many researchers have become interested in synthesizing short-chain compounds based on conjugated molecules because they are not amorphous and can be synthesized as well-defined structures [6]. Moreover, the short ...
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9 (Thio 2′ methyl 4′ nitrophenyl) acridine
... Acridine derivatives are currently delivered to animals as antihelminthics agents (Durchheimer et ...addition, acridine derivatives have shown in vitro activity against protozoan-like ...
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14 n Butyldibenz[a,h]acridine
... Use of alkylated acridine derivatives in molecular recognitions have made enormous strides in recent years (Pan et al. , 2000). Regioselective alkylation of polycyclic benz and dibenz acridines not only ...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF CHALCONE DERIVATIVES OF ACRIDINES AS ANTICANCER AGENTS
... fused acridine derivatives (10a-j) was evaluated on three human cancer cell lines such as MCF-7 (Beast), A549, MDA MB-231 (lung) by using the MTT assay and these results are summarized in Table ...
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trans Bis(acridine κN)dichloridopalladium(II)
... atoms are in trans conformation with respect to each other and almost perpendicular to the acridine planes, with the bond angle N1—Pd1—Cl1 = 89.75 (12)°. In the crystal, the complex molecules are stacked in ...
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GENETIC STUDIES OF ACRIDINE-INDUCED MUTANTS IN STREPTOCOCCUS PNEUMONIAE
... A further study of the revertants obtained by quinacrine treatment of quinacrine-induced mutants strengthens this interpretation: most of the revertants result from a mut[r] ...
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5bα,6,7,13bα,14,15 Hexahydroacridino[4,3 c]acridine
... The title compound was prepared as racemic material by Friedländer condensation (Cheng & Yan, 1982), but the crystallization process resulted in self-resolution and formation of a conglomerate (Collet et al. , 1980; ...
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2,6 Dibromophenyl acridine 9 carboxylate
... The acridine and benzene ring systems are planar, with average deviations of 0.012 (3) and 0.005 (3) A ˚ , respectively. The least-squares planes (defined by all non-H atoms) of the acridine and benzene ...
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SOME ACRIDINE-RESISTANT MUTATIONS OF BACTERIOPHAGE T4D
... pr and ac are homologous genes (SUSMAN, unpublished results) .) Since 9AA uptake is not amenable to fluorescence measurements (un-.. The infected cells were diluted IQO-fold [r] ...
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Acridine Sensitivity of Bacteriophage T2H in Escherichia coli
... Photoinactivation of the phage progeny Bacteriophage genotype showed that the two genotypes which contained Expt Proflavine the pr mutation had the same photoinactivation prds+ prds4 pr+[r] ...
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Growth and Study of ADP Crystal Doped with Acridine Orange
... [1]. Acridine Orange, due to its meta chromic properties, is commonly used in fluorescence microscopy and flow cytometry analysis of cellular physiology and cell cycle status, including the fluorescent microscopic ...
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Isolation of flavonol rhamnosides from Pometia pinnata leaves and investigation of α-glucosidase inhibitory activity of flavonol derivatives
... of the bark also was reported to have α-glucosidase and α-amylase inhibitory activities (Elya et al., 2015). Recently, the tyrosinase inhibitory activities from the ethanol extract of the bark and leaves were studied ...
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The Effect of Vitamin E and Selenium on Sperm Chromatin Quality in Couples with Recurrent Miscarriage
... Evaluation of sperm’s chromatin quality with acridine orange test, chromomycin A3 and aniline blue staining in couples with unexplained recurrent abortion.[r] ...
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