activating peptide
Increased plasma levels of epithelial neutrophil-activating peptide 78/CXCL5 during the remission of Neuromyelitis optica
... Background: In neuromyelitis optica (NMO), one of the underlying pathogenic mechanisms is the formation of antigen-antibody complexes which can trigger an inflammatory response by inducing the infiltration of neutrophils ...
6
Epithelial neutrophil activating peptide (ENA 78) is an important angiogenic factor in non small cell lung cancer
... We report here the role of the CXC chemokine, epithelial neutrophil activating peptide (ENA-78), as an angiogenic factor in human non-small cell lung cancer (NSCLC). In freshly isolated human specimens of ...
9
Epithelial neutrophil activating peptide 78: a novel chemotactic cytokine for neutrophils in arthritis
... We and others have shown that cells obtained from inflamed joints of rheumatoid arthritis (RA) patients produce interleukin-8, a potent chemotactic cytokine for neutrophils (PMNs). However, IL-8 accounted for only 40% of ...
8
Enhanced production of neutrophil activating peptide 1/interleukin 8 in rheumatoid arthritis
... Production of the neutrophil-activating peptide (NAP)-1/IL-8 by mononuclear phagocytes from patients with RA and from control subjects was studied under various conditions. Mononuclear cells from bone ...
8
Relationship of one form of human histamine releasing factor to connective tissue activating peptide III
... mitogenesis and extracellular matrix formation in fibroblast cultures. 19 of 21 NH2-terminal residues in the top half of the HRF band were identical to the NH2-terminal sequence of CTAP-III. 20 of 21 NH2-terminal ...
7
Effects of thrombin, PAR-1 activating peptide and a PAR-1 antagonist on umbilical artery resistance in vitro
... plays a role in blood coagulation, but its effects in many other cell and tissue types (smooth muscle cells, endothe- lial cells, lymphocytes) [5,6] have been the subject of more recent attention. It is now apparent that ...
7
Neutrophil activating peptide 1/interleukin 8, a novel cytokine that activates neutrophils
... In vivo inflammatory activity of neutrophil-activating factor, a novel chemotactic peptide derived from human monocytes.. A novel, NH2-terminal sequence-characterized human monokine poss[r] ...
6
Contribution of blood platelets to vascular pathology in Alzheimer's disease
... tissue-activating peptide III (CTAP-III), platelet factor 4 (PF4), regulated upon activation normal T-cell expressed and presumably secreted (RANTES), and macrophage inflammatory protein (MIP)-1 α , ...
7
Activation of proteinase activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study
... Protein modulation was investigated in OA cartilage explants treated with a specific PAR-2-activating peptide PAR-2-AP, SLIGKVNH2 1 to 400 μM, interleukin 1 beta IL-1β 100 pg/mL, tumor n[r] ...
10
Localization and function of VIP and PACAP in the heart
... intestinal peptide (VIP) is a linear 28-amino-acid peptide with molecular weight of 3,326 Da that is generated by enzymatic cleavage from its precursor molecule, ...of peptide histidine methionine, ...
6
Enhancement of incisional wound healing and neovascularization in normal rats by thrombin and synthetic thrombin receptor activating peptides
... receptor-activating peptide (TRAP-508) or human alpha-thrombin in saline enhances 7-d incisional breaking strength in normal rats up to 82% or 55% over saline-treated controls, ...
10
A role for proteinase activated receptor–1 in inflammatory bowel diseases
... age score was assessed as previously described (44), scoring inflammatory parameters such as erythema, hemorrhage, edema, stricture formation, ulceration, presence of blood in the feces, mucus presence, diarrhea, and ...
14
Photoactivated antiviral and antitumor compositions
... an activating chemical. The expression of the activating chemical is regulated so as to target the virus-infected or tumor ...the activating chemical is accomplished by a number of methods including ...
30
Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies
... for activating FcR coengagement for antibodies targeting costimulatory and inhibitory cell surface targets within the T cell–APC interface supports the possibil- ity of using antibody engineering to enhance their ...
10
Photoactivated antiviral and antitumor compositions
... an activating chemical. The expression of the activating chemical is regulated so as to target the virus-infected or tumor ...the activating chemical is accomplished by a number of methods including ...
28
Relationships Between Prior Experiences, Current Teaching Contexts, and Novice Teachers' Use of Concrete Representation for Mathematics Instruction
... a peptide corresponding to residues 73-92 (hereinafter referred to as BMP-2 peptide) showed highest alkaline phosphatase (ALP) and osteogenic differentiation of MSCs, but the peptide activity was ...
238
<p>KLF6 Induces Apoptosis in Human Lens Epithelial Cells Through the ATF4-ATF3-CHOP Axis</p>
... ATF3, activating transcription factor 4; ATF4, activating transcription factor 3; ATF6, activating transcription factor 6; ATF/CREB, ATF/ cAMP response element binding; Bax, Bcl-2-associated X ...
15
Effect of montelukast on platelet activating factor- and tachykinin induced mucus secretion in the rat
... Platelet activating factor and tachykinins (substance P, neurokinin A, neurokinin B) are important mediators contributing to increased airway secretion in the context of different types of respiratory diseases ...
6
Vasonatrin peptide: a unique synthetic natriuretic and vasorelaxing peptide
... The structures of human atrial natriuretic peptide h-ANP, human C-type natriuretic peptide h-CNP, and vasonatrin peptide VNP... The Biology of Vasonatrin Peptide..[r] ...
6
The Arf GTPase Activating Protein Family Is Exploited by Salmonella enterica Serovar Typhimurium To Invade Nonphagocytic Host Cells
... ABSTRACT To establish intracellular infections, Salmonella bacteria trigger host cell membrane ruffling and invasion by sub- verting cellular Arf guanine nucleotide exchange factors (GEFs) that activate Arf1 and Arf6 ...
11