Activating transcription factor 2
VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions
... growth factor A (VEGF-A) regulates many aspects of vascu- lar ...and activating transcription factor-2 ...growth factor isoforms program complex cellular outputs and responses by ...
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Metastatic biomarkers in synovial sarcoma
... (BRG-/BRM-associated factor) complexes affect- ing the integration of a tumor suppressor component and consequent SRY (sex-determining region Y)-box 2 (SOX2) activation which stimulates cell proliferation ...
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Notch signaling in pediatric soft tissue sarcomas
... protein activating transcription factor 2 (ATF2) ...the transcription of ATF2-induced genes, such as cell cycle regulator and apop- totic genes, resulting in tumor cell ...Complex ...
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Developmental hypomyelination in Wolfram syndrome: new insights from neuroimaging and gene expression analyses
... ATF6: Activating transcription factor 6; BiNGO: Biological network gene ontology tool; Ca 2+ : Calcium; CC: Corpus callosum; CHD: Congenital heart disease; CNS: Central nervous system; CSEA: ...
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Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells
... and activating transcription factor 6 (ATF6) implement the ER stress response ...initiation factor 2 (eIF2α), which inhib- its assembly of the 80S ribosome and protein ...pivotal ...
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Contribution of Activating Transcription Factor 3 to development of acinar-to-ductal cell metaplasia
... PVDF membranes (BioRad; Herculus, CA) at 200 mA for 90 minutes. Following transfer, the membrane was rinsed with PBS and incubated at room temperature for 1 hour in dissolved 5% non-fat dried milk (NFDM) in PBS for 60 ...
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Proteostatic Signaling & Control of Protein Synthesis
... initiation factor 2 ...(uORFs). Activating Transcription Factor 4 (ATF4) is the most well-understood p- eIF2a activated uORF and has earned a reputation as a stress- induced ...
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Activating transcription factor 6 derepression mediates neuroprotection in Huntington disease
... Repaglinide-treated R6/2 mice showed improved perfor- mance in the rotarod test. Latency was reduced in DMSO-treated R6/2 compared with WT mice at all ages tested, which was sig- nificant from 10 weeks of ...
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Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines
... Kruppel‑like factor 6 (KLF6), activating transcription factor 3 (ATF3) and p21, while down‑regulating the expression of selected oncogenes, including E2F transcription factor 1 ...
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Uncovering Dual Roles for PERK Signaling During Experimentally Induced Pancreatitis
... (Ca 2+ ), and induction of the unfolded protein response ...members Activating Transcription Factor (ATF) 3 and stanniocalcin (STC) ...
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Herpesviruses and the Unfolded Protein Response
... (PERK), Activating Transcription Factor 6 (ATF6), and Inositol-Requiring Enzyme 1 (IRE1), that are normally maintained in an inactive state by the abundant ER chaperone Binding-Immunoglobulin Protein ...
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Myxoma virus attenuates expression of activating transcription factor 4 (ATF4) which has implications for the treatment of proteasome inhibitor–resistant multiple myeloma
... (Figures 2), these data suggest that combination therapy with MYXV and BTZ in nonresistant patients might be counterproductive since viral infection would prevent the primary mechanism of action of the ...
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Activating transcription factor 4 regulates osteoclast differentiation in mice
... tured in methylcellulose semisolid medium in 35-mm dishes in the presence of 1.0 ng/ml recombinant human GM-CSF for 10 days. The number of CFU-GM colonies was counted under an inverted microscope. Experiments were ...
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Low pH results in co ordinate regulation of gene expression in oesophageal cells
... Figure 2 details those genes whose expression was upregulated across all time periods in comparison with the resting ...accelerating factor (DAF) was observed, which has previously been reported to be ...
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Identification potential biomarkers in pulmonary tuberculosis and latent infection based on bioinformatics analysis
... ATF: Activating transcription factor; ATP1A4 : ATPase, Na+/K+ transporting, alpha 4 polypeptide; BATF : Basic leucine zipper transcription factor, ATF-like; BH: Benjamin and Hochberg; ...
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Activating transcription factor 5 enhances radioresistance and malignancy in cancer cells
... To understand the mechanism underlying radioresis- tance, we investigated how ATF5 regulates radioresistance. We hypothesized that ATF5 enhances radioresistance via regulation of the cell cycle because ATF5 expression ...
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Differential expression of two activating transcription factor 5 isoforms in papillary thyroid carcinoma
... Background: Activating transcription factor 5 (ATF5) is a member of the activating transcription/cAMP response element-binding protein family of basic leucine zipper proteins that plays ...
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Dysfunction of various organelles provokes multiple cell death after quantum dot exposure
... ATF4, activating transcription factor 4; ATF6, activating transcription factor 6; Bak, Bcl-2 antagonist/killer 1; Bax, Bcl-2-associated X protein; Bcl-2, ...
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Ectopic Expression of Hepatitis C Virus Core Protein Differentially Regulates Nuclear Transcription Factors
... nuclear factor-kB (NF-kB)- and activating protein-1 (AP-1)-specific recognition sequences present in the promoters of a large number of genes known to be involved in inflammation control and immune ...
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Involvement of Template-Activating Factor I/SET in Transcription of Adenovirus Early Genes as a Positive-Acting Factor
... Fig. 2 indicate that pp32 seems to have less affinity to protein VII than ...inhibitory factor(s) to the Ad DNA for transcription through protein ...
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