Activin A
Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes
... of activin A and TGFB1 on endogenous Fshb mRNA ...with activin A resulted in a 31-fold stimulation of Fshb mRNA ...tures, activin A and TGFB1 exerted similar effects on Fshb expression to those seen ...
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Activin A: an autocrine inhibitor of initiation of DNA synthesis in rat hepatocytes
... When activin A was added together with EGF, DNA synthesis induced by EGF was markedly ...M activin A almost completely blocked EGF- mediated DNA ...Similarly, activin A completely blocked DNA ...
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The glycoprotein-hormones activin A and inhibin A interfere with dendritic cell maturation
... members of the transforming growth factor beta family (TGF-β), namely activin A (ActA) and inhibin A (InA), are present in the serum at dynamic levels during the first tri- mester of human pregnancy [3]. Both ...
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Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma
... and Activin A neutralizing antibody were used as additional controls in this assay to demonstrate the specificity of the function of Activin A in cell invasion (Supplemental Figure ...the Activin A ...
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Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B
... al. Activin A inhibits BMP-signaling by binding ACVR2A and ...with activin A (10 ng/ml) or TGF- β (5 ng/mL) with or without BMP-6 (25 ng/mL) and BMP-9 ...with activin A (10 ng/ml) or TGF- β (5 ...
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High Levels Production of Recombinant Human Activin A—Effect upon in Vivo Follicle Stimulation
... [30]-[32]. Activin is one of these growth ...with activin A was observed in rodents and showed their autocrine and paracrine role in the structural and functional development of follicles [31] [33] ...which ...
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Activin a is associated with impaired myocardial glucose metabolism and left ventricular remodeling in patients with uncomplicated type 2 diabetes
... of the regression models was judged based on histograms and scatter plots. Additional potential con- founders were investigated by adding age, BMI, systolic BP (SBP), diastolic BP (DBP), HR, fasting glu- cose, and ...
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Activin A expression regulates multipotency of mesenchymal progenitor cells
... high activin A expression level as well as the highest chondrogenic potential among the MPCs tested, we next determined the role of activin A in their multipotency by silencing of activin A in ...
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Enhanced Expression of Recombinant Activin A in Escherichia coli by Optimization of Induction Parameters
... of activin A, we used dot blotting analysis in which an anti-his tag monoclonal antibody recognized recombinant activin A in the extracted protein sample (Fig ...recombinant activin A, the areas of ...
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Betacellulin and activin A coordinately convert amylase secreting pancreatic AR42J cells into insulin secreting cells
... lack of a response to betacellulin in the majority of the AR42J cells may result from the polyclonal origin of AR42J cells. From a biochemical point of view, it is likely that only a few cells express enough betacellulin ...
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Activin A as an intraovarian modulator: actions, localization, and regulation of the intact dimer in human ovarian cells
... inhibin-A, activin-A, or phorbol 12-myristate 13-acetate, increased the immunostaining for activin-A in cultured granulosa ...that activin-A may function as an autocrine or paracrine regulator of ...
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Activin-A up-regulates type I activin receptor mRNA levels in human immortalized extravillous trophoblast cells.
... by activin, and in turn, Smad7 inhibits further activin sig- naling by blocking the phosphorylation of Smad2/3 by activin type I receptors ...addition, activin signal- ing can also be ...
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Serum activin A and B, and follistatin in critically ill patients with influenza A(H1N1) infection
... Serum activin A, activin B, and total FS were determined using specific ELISAs for activin A and B and by radioimmunoassay for follistatin ...for activin A, activin B and FS were ...
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The activin follistatin anti inflammatory cycle is deregulated in synovial fibroblasts
... blocking activin A [14, ...of activin A remains unclear [7, ...to activin A are liver cells as shown for the human hepatocellular carcinoma cell line HepG2 ...vitro, activin A decreased ...
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Activin promotes oocyte development in ovine preantral follicles in vitro
... For the control group, preantral follicles (n = 34) were cul- tured individually in 96 well plates (Bibby Sterilin Ltd. Stone, Staffs, UK) in 250 µl of culture medium (McCoy's 5a medium with bicarbonate supplemented with ...
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Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants
... of activin in pancreatic rudiments of rat embryos and stimulation of insulin secretion from adult rat pancreatic islets by activin, activin is implicated in the de- velopment and function of ...of ...
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Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody
... Abbreviations ACVR2A: activin A receptor type 2A; ACVR2B: activin A receptor type 2B; ACVR1: activin A receptor type 1; BMP: bone morphogenetic protein; BMPR2: BMP type 2 receptor; BMPR2[r] ...
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GATA4, 5 and 6 mediate TGFβ maintenance of endodermal gene expression in Xenopus embryos
... by activin (a mimic for Nodal signalling), and if the induction of Sox17 α or HNF1 β by activin is via GATA4, 5 or ...of activin RNA were injected into the animal pole of Xenopus embryos at the ...
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Transforming growth factor beta family expression at the bovine feto-maternal interface
... analyze activin-like protein expression, BT-1 cell extracts (100 μg) and supernatants (200 μL) were applied to Western blotting, as described previously with some modifications ...purified activin A were ...
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Effects of non steroidal gonadal factors on LH secretion in female common carp during the reproductive cycle
... For in vitro experiments 12 fishes at the stage of gonad recrudescence and 10 fishes at the preovula- tory stage of gonad maturity were used. All cultures were done according to the protocol established by Weil et al. ...
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