Acute myelogenous leukemia (AML)
Computerized Detection System for Acute Myelogenous Leukemia in Blood Microscopic Images
... platelets. Leukemia is detected only by observing the ...WBC’s. Leukemia is categorized into chronic leukemia and acute ...viz. Acute Lymphocytic Leukemia (ALL), Acute ...
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Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells
... to leukemogenesis, and targeted therapies involving NF-κB have been designed to induce LSCs-specific apoptosis [14]. Two regulators of NF-κB that have been implicated as tumor suppressor genes, DAPK and IRF-1, have been ...
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Original Article Tim-3 as a leukemia stem cell specific marker expressing on bone marrow mononuclear cells is a factor for prognosis evaluation in patients with acute myelogenous leukemia
... of acute myelogenous leukemia (AML), however, the alterations of Tim-3, as well as its marker and prognostic significance has yet to be evaluated in patients with ...
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The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients
... The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) signaling axis plays a central role in cell proliferation, growth, and survival under physiological conditions. However, aberrant ...
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Pulmonary Infection Caused by Gymnascella hyalinospora in a Patient with Acute Myelogenous Leukemia
... pancytopenia plus circulating blasts and a diagnosis of acute myelogenous leukemia (FAB-M1) was made. Induction che- motherapy, consisting of idarubicin and cytarabine, was admin- istered, and the ...
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Definition of a possible genetic basis for susceptibility to acute myelogenous leukemia associated with the presence of a polymorphic Ia epitope
... The polymorphic Ia epitope recognized by monoclonal antibody 109d6 is detectable on the leukemic cells of a significantly increased number of individuals with acute myelogenous leukemia, compared ...
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Measurement of the hypercoagulability state in Sudanese patients with acute myelogenous leukemia in Khartoum state
... with acute myelogenous leukemia in Khartoum state between November 2015 and April ...were Acute Myelogenous Leukemia patients and 40 from healthy individual as control (Same age ...
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Case Report Ovarian granulocytic sarcoma as the primary manifestation of acute myelogenous leukemia
... of acute myeloid leukemia (AML) or other myeloproliferative disorders, however, GS of the ovary as the primary manifestation of AML is exceed- ingly ...
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Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia
... In this study, we examined blood and/or bone marrow samples from relapsed/refractory AML (r/r AML) patients enrolled in phase I/II trials of guadecitabine for their DNA methylation statu[r] ...
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Stem cell therapeutics: potential in the treatment of inflammatory bowel disease
... ALL, acute lymphocytic leukemia; AML, acute myelogenous leukemia; ATG, antithymocyte globulin; BMSC, bone mar- row stem cells; BMT, bone marrow transplant; CD, Crohn’s disease; CML, ...
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High rates of submicroscopic aberrations in karyotypically normal acute lymphoblastic leukemia
... ALL: Acute lymphoblastic leukemia; aMCB: Array-proven multicolor-banding; AML: Acute myelogenous leukemia; BAC: Bacterial artificial chromosome; B-ALL: B-cell ALL; Bp: Basepairs; CLL: ...
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Prophylaxis and treatment of invasive aspergillosis with voriconazole, posaconazole and caspofungin - review of the literature
... in acute leukemia and in the allogeneic hematopoietic stem cell transplant (HscT) setting [17, ...with acute myelogenous leukemia (AMl) or myelodysplas- tic syndrome (Mds) that had a ...
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Mutations of c-Cbl in myeloid malignancies
... categories: acute myelogenous leukemia (AML) characterized by accumulation of immature myeloid cells in the bone marrow, myelodypastic syndromes (MDS) associated with ineffective hematopoiesis and ...
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Effectiveness of AMD3100 in treatment of leukemia and solid tumors: from original discovery to use in current clinical practice
... AML: acute myelogenous leukemia; BMSC: bone marrow stromal cell; CDC: Centers for Disease Control and Prevention; CLL: chronic lymphocytic leukemia; CML: chronic myeloid leukemia; ...
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Pretreatment of cytokinetics in acute myelogenous leukemia Age related prognostic implications
... This age-related divergent effect of cell cycle kinetics on initial response to therapy was confined to the less favorable subgroup of patients with karyotypic abnormalities, whereas pat[r] ...
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DNA damage response and cancer therapeutics through the lens of the Fanconi Anemia DNA repair pathway
... Fanconi Anemia (FA), a rare genetic cancer-susceptibility syndrome is a recessive autosomal or X-linked genetic dis- ease [1–3]. FA is characterized by genomic instability, bone marrow failure leading to progressive ...
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Clinical significance of high-dose cytarabine added to cyclophosphamide/total-body irradiation in bone marrow or peripheral blood stem cell transplantation for myeloid malignancy
... AML: acute myelogenous leukemia; BMT: bone marrow transplantation; CBT: cord blood transplantation; CI: confidence interval; CY: cyclophosphamide; GVHD: graft-versus-host disease; GVL: graft versus ...
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Supervise Method for Acute Lymphoblastic Leukemia Segmentation and Classification
... of leukemia are Acute Myelogenous Leukemia (AML); Acute Lymphoblastic Leukemia (ALL); Chronic Myeloid Leukemia (CML); Chronic Lymphocytic Leukemia ...
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Adoption of M- Wallet: A way Ahead
... earlier Acute Myelogenous leukemia (AML) diagnosis and treatment require sophisticated software and hardware ...of leukemia detection arises since current methods involve manual examination of ...
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EFFECT OF LONG- AND SHORT-TERM MINICONSOLIDATION ON SURVIVAL OF PATIENTS WITH ACUTE MYELOGENOUS LEUKEMIA
... The difference between these two is the duration of therapy, The finding of in significant difference between these two forms of mini consolidation therapy confirm tha[r] ...
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