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adaptive immune response

Deletion of the Monkeypox Virus Inhibitor of Complement Enzymes Locus Impacts the Adaptive Immune Response to Monkeypox Virus in a Nonhuman Primate Model of Infection

Deletion of the Monkeypox Virus Inhibitor of Complement Enzymes Locus Impacts the Adaptive Immune Response to Monkeypox Virus in a Nonhuman Primate Model of Infection

... mune response to MPXV infection and to assess the role of MOPICE in MPXV disease, we further developed the rhesus macaque (RM) (Macaca mulatta) model of MPXV infection utilizing the pathogenic Zaire strain of MPXV ...

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Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

Quantifying the Early Immune Response and Adaptive Immune Response Kinetics in Mice Infected with Influenza A Virus

... the immune response kinetics to IAV infection and which biological parameters most strongly influence infection ...and adaptive immune responses to primary IAV ...and immune kinetic ...

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Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis

Multiple mycobacterial antigens are targets of the adaptive immune response in pulmonary sarcoidosis

... Th-1 immune responses to multiple mycobacterial virulence factors in sarcoidosis diagnostic bronchoalveolar ...sarcoidosis adaptive immune response, this response is heterogeneous ...

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Impact Of Host Factors On The Adaptive Immune Response To Aav Gene Therapy

Impact Of Host Factors On The Adaptive Immune Response To Aav Gene Therapy

... Adaptive immune responses to the transgene product remain an active area of concern for the gene therapy ...the immune system is an important consideration in the development of gene therapy for ...

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Myeloid suppressor cells regulate the adaptive immune response to cancer

Myeloid suppressor cells regulate the adaptive immune response to cancer

... Another major finding of the current study (10) is that MSCs express IL-4 recep- tor α (IL-4Rα), an observation that may be useful for the targeted deletion or inactiva- tion of MSCs in vivo. It may also provide an ...

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Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co infected school aged children from an endemic area of Lambaréné, Gabon

Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co infected school aged children from an endemic area of Lambaréné, Gabon

... the immune profile seen in asymptomatic ...inflammatory response that is thought to allow the survival of the parasites ...innate immune response of schistosome-infected ...the adaptive ...

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Key roles for lipid mediators in the adaptive immune response

Key roles for lipid mediators in the adaptive immune response

... recruits immune cells to the site of tissue damage or infection and is some- times followed by an eventual return to ...inflammatory response is characterized by lipid mediator “class switching,” in which ...

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Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

... The immune response to respiratory infection with in- fluenza virus involves several lymphoid and nonlymphoid anatomical compart- ...innate immune response to influenza virus, such as secre- ...

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Adaptive immune response in human Staphylococcus aureus bloodstream infection

Adaptive immune response in human Staphylococcus aureus bloodstream infection

... antigen-specific adaptive immunity (particularly the first report of adaptive cellular immune response) in the early recovery period of bloodstream infection is considerably important even in ...

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Systemic Expression of Galectin Genes in Periparturient Goats

Systemic Expression of Galectin Genes in Periparturient Goats

... involvement in both the innate and adaptive immune response to gastrointestinal parasite infection. 295[r] ...

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Mounting a specific immune response increases energy expenditure of the subterranean rodent Ctenomys talarum (tuco tuco): implications for intraspecific and interspecific variation in immunological traits

Mounting a specific immune response increases energy expenditure of the subterranean rodent Ctenomys talarum (tuco tuco): implications for intraspecific and interspecific variation in immunological traits

... an immune challenge but we also explored the magnitude of the associated antibody ...the response against SRBC, estimated by the mean antibody titres against this antigen detected in hemoagglutination ...

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Lethal Silver-Haired Bat Rabies Virus Infection Can Be Prevented by Opening the Blood-Brain Barrier

Lethal Silver-Haired Bat Rabies Virus Infection Can Be Prevented by Opening the Blood-Brain Barrier

... CNS adaptive immune response are unlikely to be responsible for the variation in the levels of virus in the CNS of dying and healthy mice for several reasons: (i) the accumulation of mRNAs specific ...

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The role of leptin in innate and adaptive immune responses

The role of leptin in innate and adaptive immune responses

... the adaptive immune ...innate immune system, causing inflammation of the injected joint ...acute-phase response during zymosan-induced arthritis compared to their lean littermates ...

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Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development

... (ii) Assessment of the impact of polysaccharide size, structure, functionalization, and conformation on immune responses to the conjugated polysaccharide. It is commonly accepted that oligosaccharide antigens with ...

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The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice

The Carbomer-Lecithin Adjuvant Adjuplex Has Potent Immunoactivating Properties and Elicits Protective Adaptive Immunity against Influenza Virus Challenge in Mice

... the adaptive immune response to newly developed ...Th1-/Th2-type immune responses with accompanying cytokines and triggered antigen-specific CD8 ⴙ T-cell ...

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The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018

The great debate at “Immunotherapy Bridge 2018”, Naples, November 29th, 2018

... of adaptive immunity T-cells are clearly responsible for killing tumor cells, while the innate immune system can be subverted to promote the growth of cancer via tumor recruitment of suppressive myeloid ...

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Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier

Optimization of secretion and surface localization of heterologous OVA protein in mycobacteria by using LipY as a carrier

... the adaptive immune response against Mycobacterium tuberculosis antigens [43], we aimed to optimize heterologous secretion in mycobacteria by using the ESX-5 system and assessing both secretion and ...

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Review Article Thymic Stromal Lymphopoietin (TSLP) as a Bridge between Infection and Atopy

Review Article Thymic Stromal Lymphopoietin (TSLP) as a Bridge between Infection and Atopy

... and adaptive immune response, but there is evidence that it may directly activate mast cells (MC) [36], which have a pivotal role during allergy ...

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What Fuels Natural Killers? Metabolism and NK Cell Responses

What Fuels Natural Killers? Metabolism and NK Cell Responses

... NK cell activation commences to produce sustained NK cell activation and functioning in parallel and in concert with the adaptive immune response. These exact activities remain to be defined but ...

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Preferential Infection of Mature Dendritic Cells by Mouse Hepatitis Virus Strain JHM

Preferential Infection of Mature Dendritic Cells by Mouse Hepatitis Virus Strain JHM

... The adaptive immune response to murine coronaviruses has been partially ...body response is also present in infected mice and is critical for preventing virus recrudescence ...T-cell ...

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