Adeno-associated virus
Expression Profiles of Bovine Adeno-Associated Virus and Avian Adeno-Associated Virus Display Significant Similarity to That of Adeno-Associated Virus Type 5
... nonprimate-derived adeno-associated viruses, namely, bovine adeno-associated virus (B-AAV) and avian adeno-associated virus (A-AAV), which were obtained after the ...
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Adeno-associated virus vector integration junctions.
... Department of Medicine and Markey Molecular Medicine Center, University of Washington, Seattle, Washington 98195 Received 29 April 1997/Accepted 31 July 1997 Vectors derived from adeno-associated ...
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Structure of Adeno-Associated Virus Type 4
... 2004 Adeno-associated virus (AAV) is a member of the Parvoviridae, belonging to the Dependovirus ...disease virus and human parvovirus B19, autonomous members of the genus, despite limited ...
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Structure of Adeno-Associated Virus Serotype 5
... Adeno-associated virus serotype 5 (AAV5) requires sialic acid on host cells to bind and ...minute virus of mice, and bovine parvovirus, also bind sialic ...
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In Vitro Packaging of Adeno-Associated Virus DNA
... recombinant adeno-associated virus ...mature virus particles but not bound by an antibody that recognizes monomeric or denatured capsid ...DNA virus particle is assembled, and it may be ...
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Genetic analysis of adeno-associated virus: properties of deletion mutants constructed in vitro and evidence for an adeno-associated virus replication function.
... Transfection of a pBR322-based, recombinant plasmid, pAV2, containing the entire adeno-associated virus (AAV) type 2 genome into human 293 cells in the presence of helper adenovirus resu[r] ...
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Intermediates of adeno-associated virus DNA replication in vitro.
... replication of parvovirus and linear chromosomal DNA. In vitro rescue of an integrated hybrid adeno-associated virus/simian virus 40) genome.[r] ...
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Structural Insights into Adeno-Associated Virus Serotype 5
... 2012. Gene therapy for retinitis pigmentosa caused by MFRP mutations: human phenotype and preliminary proof of concept. Hum. Gene Ther. 23:367–376. 39. Jacobson SG, Acland GM, Aguirre GD, Aleman TS, Schwartz SB, ...
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Properties of the Adeno-Associated Virus Assembly-Activating Protein
... Adeno-associated virus (AAV) capsid assembly requires expression of the assembly-activating protein (AAP) together with cap- sid proteins VP1, VP2, and ...
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Transcriptional Analysis of the Adeno-Associated Virus Integration Site
... human adeno-associated virus type 2 (AAV-2) has adopted a unique mechanism to site-specifically integrate its genome into the human MBS85 gene, which is embedded in AAVS1 on chromosome ...
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Gangliosides Are Essential for Bovine Adeno-Associated Virus Entry
... 14). Adeno-associated viruses are members of the genus De- pendovirus, a small group of viruses that were classified based on similar size and structure and dependence upon a helper virus for ...
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Characterization of the Mouse Adeno-Associated Virus AAVS1 Ortholog
... The nonpathogenic human adeno-associated virus (AAV) has developed a mechanism to integrate its genome into human chromosome 19 at 19q13.4 (termed AAVS1), thereby establishing latency. Here, we ...
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Cloning and Characterization of Adeno-Associated Virus Type 5
... JOHN A. CHIORINI, FRANK KIM, LINDA YANG, AND ROBERT M. KOTIN* Molecular Hematology Branch, National Heart, Lung and Blood Institute, Bethesda, Maryland 20892 Received 26 August 1998/Accepted 30 October 1998 ...
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Adeno-Associated Virus as a Vector for Liver-Directed Gene Therapy
... the Wistar Institute, Philadelphia, Pennsylvania Received 10 April 1998/Accepted 2 September 1998 Factors relevant to the successful application of adeno-associated virus (AAV) vectors for ...
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Subcellular compartmentalization of adeno-associated virus type 2 assembly.
... Received 12 July 1996/Accepted 28 October 1996 Using immunofluorescence and in situ hybridization techniques, we studied the intracellular localization of adeno-associated virus type 2 (AAV-2) Rep ...
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In vivo model of adeno-associated virus vector persistence and rescue.
... DNA virus vectors, such as adenovirus (Ad) and adeno-associated virus (AAV), are being developed for gene therapy of a number of human ...
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Comparative Analysis of Adeno-Associated Virus Capsid Stability and Dynamics
... of adeno-associated virus (AAV), AAV1, AAV2, AAV5, and AAV8, were compared with respect to the physical properties of their capsids that influence thermody- namic ...
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cis Effects in Adeno-Associated Virus Type 2 Replication
... of adeno-associated virus (AAV) to investigate which elements of the AAV genome are required in cis for high yields of the wild-type virus in a plasmid transfection assay and in addition ...
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Effects of Adeno-Associated Virus DNA Hairpin Structure on Recombination
... the adeno-associated virus (AAV) genome are substrates for recombination that give rise to persistent circular and concatemeric DNA episomes through intramolecular and intermolecular recombination, ...
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Recent advances in recombinant adeno-associated virus vector production
... of adeno-associated virus ...recombinant adeno- 20. Gao GP, Qu G, Faust LZ, et al: High-titer adeno-associated viral associated virus production by a stable rep-cap ...
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