adiponectin gene (ADIPOQ)
Haplotypes and sequence variation in the ovine adiponectin gene (ADIPOQ)
... human adiponectin gene (ADIPOQ) was first identified in 1995 and is located on human chromosome 3q27 ...human gene has been reported to be associated with obesity, type 2 diabetes ...
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Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes
... rs266729 of the adiponectin gene was not associated with CAD (OR =1.24, 95%CI: 0.91-1.69, p= 0.20) in a 435 Chinese population study, but female carriers of allele G at rs266729 had a higher risk of CAD ...
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Relationship between polymorphism of insulin receptor gene, and adiponectin gene with PCOS
... Basic, reproductive and metabolic characteristics of study subjects are presented in table II. The prevalence of primary infertility and familial history of hirsutism among PCOS participants were significantly more than ...
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Adiponectin Gene Polymorphism SNP +45 T/G in Type 2 Diabetic Patients in Assam, India
... non-diabetic controls were selected from Guwahati, which has an average age of 25-64 years (n = 80). Patients with type 2 diabetes from the Diabetes Clinic were selected based on the following criteria: presence of ...
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Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome
... the ADIPOQ promoter has no classical CpG island and contains a low number of CpG sites (chromo- somal location chr3:186,556,516-186,580,200, UCSC Genome browser on human ...for ADIPOQ gene regulation ...
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Association of adiponectin gene variants with idiopathic recurrent miscarriage according to obesity status: a case–control study
... 14 ADIPOQ variants tested, the minor allele frequency (MAF) of rs4632532, rs17300539, rs266729, rs182052, rs16861209, and rs7649121 were significantly higher, while rs2241767, and rs1063539 MAF were lower in RPL ...
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Association of the Adiponectin Gene Variations with Risk of Ischemic Stroke in a Korean Population
... For each OR, we calculated 95% CIs. Association analysis of the haplotypes was performed using Haploview (v 4.1). Logistic regression models were used to estimate odds ra- tios that assessed the association between ...
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A single nucleotide polymorphism in ADIPOQ predicts biochemical recurrence after radical prostatectomy in localized prostate cancer
... the adiponectin gene with respect to clinical outcomes of ...the ADIPOQ gene. Although we chose to sequence three ADIPOQ SNPs based on previous study findings, some possible significant ...
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Single nucleotide polymorphism rs3774261 in the AdipoQ gene is associated with the risk of coronary heart disease (CHD) in Northeast Han Chinese population: a case-control study
... the AdipoQ gene has dual rela- tions with CHD (depending on the focus of polymorphism studied) – a risk factor for CHD (related to rs3774261G) and a protective role against CHD (related to SNP ...
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EVALUATION OF SERUM ADIPONECTIN AND ADIPOQ +45 T>G POLYMORPHISM WITH METABOLIC SYNDROME IN TUNISIAN POPULATION
... of adiponectin are regulated by gene expression, and analysis of the adiponectin gene sequence reveals a large number of ...between adiponectin SNPs and various ...of adiponectin ...
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Association of <em>ADIPOQ</em> +45T>G polymorphism with body fat mass and blood levels of soluble adiponectin and inflammation markers in a Mexican-Mestizo population
... the Adiponectin gene (ADIPOQ) expression has been associated with a systemic low-grade inflammatory ...between ADIPOQ +45T.G gene simple nucleotide polymorphism (SNP rs2241766) with ...
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AMPK -1 , and lower APOB gene expression in the liver than 42-day-old broilers. Age had no effect on FAS gene expression. Our results show that the gender and age could act on the expression of genes related to
... the adiponectin gene (ADIPOQ). After ligation of adiponectin to its receptor, the phosphorylation of AMPK occurs (Yamauchi et ...reduced ADIPOQ expression observed in birds at 42 days ...
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Reduced Slc2a4/GLUT4 expression in subcutaneous adipose tissue of monosodium glutamate obese mice is recovered after atorvastatin treatment
... Beta-actin gene; Adipoq : Adiponectin gene; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CTL: Control mice; Gapdh : Glyceraldehyde-3-phosphate dehydrogenase gene; ...
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Gene-gene interaction analysis identifies a new genetic risk factor for colorectal cancer
... T-cadherin gene ( CDH13 ) was significantly associated with CRC ( p = ...the adiponectin gene ( APN ) for CRC risk was investigated using a logistic regression ...plasma adiponectin level ...
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The influence of adiponectin G276T gene polymorphism on changes in total and high molecular weight adiponectin levels by exercise training
... that adiponectin is involved in the regulation of glucose or lipid metabolism through exercise ...the adiponectin gene con- tains a polymorphism at position 276 ...the adiponectin gene ...
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Asymmetric expression of H19 and ADIPOQ in concave/convex paravertebral muscles is associated with severe adolescent idiopathic scoliosis
... The mRNA of MSTN gene showed significantly higher expressions in concave-sided muscle tissue in the first cohort ( n = 10). But the difference was not significant in the second cohort (n = 50, Additional file 1: ...
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Low and high thermogenic brown adipocyte subpopulations coexist in murine adipose tissue
... Brown adipose tissue (BAT), as the main site of adaptive thermogenesis, exerts beneficial metabolic effects on obesity and insulin resistance. BAT has been previously assumed to contain a homogeneous population of brown ...
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T allele at ADIPOQ rs1501299 G/T polymorphism is more susceptible to the influence of circulating adiponectin on arterial stiffness in nondiabetic men
... Genotyping of ADIPOQ rs1501299 G/T polymorphism Genotyping of ADIPOQ rs1501299 G/T was performed as described previously [17, 18]. Genomic DNA was extracted from 5 mL whole blood using a commercially ...
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Effects of ADIPOQ polymorphisms on PCOS risk: a meta-analysis
... between ADIPOQ polymorphisms and PCOS risk, fifteen studies about rs1501299 polymorphism and seventeen studies about rs2241766 polymorphism were included for pooled ana- ...
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Different modulation by dietary restriction of adipokine expression in white adipose tissue sites in the rat
... The considerable diversity of expression patterns pre- sented suggest that WAT is far from being an uniform energy depot, or even behaving as a single dispersed organ. The main WAT sites studied showed different pat- ...
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