Adipose derived stem cell (ASC)
Allogenic adipose-derived stem cell therapy overcomes ischemia-induced microvessel rarefaction in the myocardium: systems biology study
... Autologous stem cell therapy was considered as an alternative; however, it has shown modest benefits due to the impairing effects of cardiovascular risk factors on stem ...Allogenic ...
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Scaffold vascularization method using an adipose-derived stem cell (ASC)-seeded scaffold prefabricated with a flow-through pedicle
... the ASC- seeded and ASC-seeded osteogenic induced groups in the previous study, whereas in our study, the ASC- seeded group showed twofold higher vessel density than the ASC-seeded osteogenic ...
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Cross-talk between microtubules and the linker of nucleoskeleton complex plays a critical role in the adipogenesis of human adipose-derived stem cells
... medium; ASC: Adipose-derived stem cell; C/EBP α : CCAAT/enhancer-binding protein α ; DAPI: 4 ′ ,6-Diamidino-2-phenylindole; DMEM: Dulbecco ’ s modified Eagle ’ s medium; FBS: Fetal ...
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Human adipose stem cell and ASC-derived cardiac progenitor cellular therapy improves outcomes in a murine model of myocardial infarction
... (BM)-derived stem cells, ASCs, and iCPs gener- ated from ASCs using three defined cardiac lineage transcription factors were assessed in an immune-compromised mouse myocardial infarction ...
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Pregnancy associated breast cancers are driven by differences in adipose stromal cells present during lactation
... glands; ASC-P: adipose stromal cells derived from pregnant mammary glands; ASC-R: adipose stromal cells derived from regressed mammary glands; BSA: bovine serum albumin; CAF: ...
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Diabetes impairs the angiogenic potential of adipose-derived stem cells by selectively depleting cellular subpopulations
... on ASC stemness, DM2 ASCs also displayed impairments in adipogenic and osteogenic differentiation in vitro (Figure 2), consistent with a loss of cell stemness and a phenotypic imprinting despite correction ...
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Therapeutic applications of adipose cell-free derivatives: a review
... ADSC: Adipose-derived stem cell; ADSC-CM: Adipose- derived stem cell-conditioned medium; ADSC-Exo: Adipose-derived stem cell exosomes; ...
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Centrifugal gravity-induced BMP4 induces chondrogenic differentiation of adipose-derived stem cells via SOX9 upregulation
... affect cell viability, ASC viability was investigated with different loading ...durations. ASC viability was increased a little after CG stimulation for 5, 15, 30, and 60 min compared to the control, ...
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Osteogenic potential of induced pluripotent stem cells from human adipose-derived stem cells
... osteogenesis: cell proliferation, extracellular matrix maturation, and ...in ASC-iPSCs expressed significantly higher levels compared with ASCs, suggesting superior osteogenic differentiation and ...
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Stem cells in clinical practice: applications and warnings
... (ADSC): Adipose Tissue-Derived Stromal Cell; (ASC): Adult Stem Cell; (ALL): Acute Lymphoblastic Leukemia; (AML): Acute Myeloid Leukemia; (ASL): Amyotrophic Lateral Sclerosis; ...
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Adipose-derived mesenchymal stem cells improve glucose homeostasis in high-fat diet-induced obese mice
... Methods: Seven-week-old C57BL/6 mice were fed a high-fat diet for 20 weeks to generate the DIO mouse model. Mice were given a single intravenous infusion of ex vivo expanded syngeneic ASCs at 2 × 10 6 cells per mouse. ...
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Human adipose derived mesenchymal stem cells attenuate collagen antibody induced autoimmune arthritis by inducing expression of FCGIIB receptors
... Furthermore, ASC treatment in- creases expression of IL-10, which might enhance T-reg function, in mice with experimental ...Th1/Th17 cell differ- entiation, and induces T-reg ...
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Low-dose strontium stimulates osteogenesis but high-dose doses cause apoptosis in human adipose-derived stem cells via regulation of the ERK1/2 signaling pathway
... medium; ASC: Adipose-derived mesenchymal stem cell; BMSC: Bone marrow stromal cell; BSA: Bovine serum albumin; COL-1: Collagen-1; Dex: Dexamethasone; ERK: Extracellular signal- ...
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Exosomes secreted by adipose derived mesenchymal stem cells regulate type i collagen metabolism in fibroblasts from women with stress urinary incontinence
... Recent studies have revealed that transplanted MSC may secrete abundant particles documented as exo- somes, which are suggested to be central mediators of intercellular communication [41]. Since the first report of ...
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Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis
... AD-MSC: Adipose-derived mesenchymal stem cell; ALD: Alcoholic liver disease; BM-MSC: Bone marrow-derived mesenchymal stem cell; CB-MSC: Cord blood- derived ...
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Prospective isolation of chondroprogenitors from human iPSCs based on cell surface markers identified using a CRISPR-Cas9-generated reporter
... pluripotent stem cells (hiPSCs) offer a promising source for cartilage tissue engineering and in vitro disease modeling [7] as they have virtually un- limited expansion capacity, can be genetically modi- fied, and ...
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Cartilage extraceullular matrix derived scaffolds for joint regeneration
... is adipose tissue, which is easy to access and possess high competent stem cell yield [122, ...the adipose-derived stem cells (ASCs) are present ...the cell yield and the ...
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ADIPOSE-DERIVED STEM CELLS IN TISSUE ENGINEERING: LABORATORY TO BEDSIDE
... 70-µm cell strainer to obtain a single cell suspension and remove the undigested ...precise cell separation technique; however, it concentrates the cells and removes fractions of cells based on ...of ...
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Distinct features of rabbit and human adipose-derived mesenchymal stem cells: implications for biotechnology and translational research
... Flow cytometry was performed in second passage rASCs and hASCs for detection of surface antigenic markers CD34, CD45, CD73, CD90, and CD105 (BD Bioscience, São Paulo, Brazil; Table 1). White blood cells fractions were ...
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Comparison of the therapeutic effects of human and mouse adipose-derived stem cells in a murine model of lipopolysaccharide-induced acute lung injury
... To advance the use of stem cell therapy in the treat- ment of ALI/ARDS it is essential that the molecular mechanisms behind any observed beneficial effects be understood. As discussed above, there is ...
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