adipose tissue triglyceride lipase
Intravenous injection of microvesicle-delivery miR-130b alleviates high-fat diet-induced obesity in C57BL/6 mice through translational repression of PPAR-γ
... ATGL: Adipose tissue triglyceride lipase; ANOVA: Analysis of variance; BCA: Bicinchoninic acid; C/EBP- β : CCTTA enhancer binding protein- β ; DMEM/F-12: Dulbecco's modified eagle's medium: ...
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The Mechanism of Activation of Hormone Sensitive Lipase in Human Adipose Tissue
... hormone-sensitive lipase to its activated form, as indicated by a decrease in the activation subsequently obtainable in fractions prepared from such hormone-treated ...hormone-sensitive triglyceride ...
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Increase of adipose tissue lipoprotein lipase activity with weight loss
... elevated adipose tissue lipoprotein lipase activity per fat cell when compared with lean control ...lipoprotein triglyceride in adipose tissue, has been shown to be further ...
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Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia
... To reveal whether low ATGL expression in cancer was a more general phenomenon, we extracted data for ATGL mRNA expression levels from four datasets of The Cancer Genome Atlas (TCGA) database. In agreement with our ...
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Heterogeneity of adipose tissue in development and metabolic function
... enhanced triglyceride storage in individual adipocytes (Martinsson, 1969) ...2). Triglyceride synthesis is facilitated by lipoprotein lipase (LPL)-mediated free fatty acid (FFA) uptake from (very) ...
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The role of adipose triglyceride lipase in lipid and glucose homeostasis: lessons from transgenic mice
... in adipose tissue [38]. Surprisingly, despite the increase in adipose TG lipolysis ATGL-over expressing mice did not display an increase in fasting ...and adipose tissue knockouts dis- ...
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JLR-2013-Yao-1058-65.pdf
... and adipose lipoprotein lipase (LPL) activity in association with upregulation of an LPL inhibitor angiopoietin-like protein 4 ...inhibits triglyceride (TG) uptake via Angptl4 and that an ...
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Endothelial lipase provides an alternative pathway for FFA uptake in lipoprotein lipase–deficient mouse adipose tissue
... Lipoprotein lipase (LPL) is responsible for the generation of fatty acids from circulating triglyceride-rich (TG-rich) ...in adipose tissue (AT) and muscle, where it is bound to the capillary ...
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The effect of estrogen on the lipoprotein lipase activity of rat adipose tissue
... of adipose tissue with doubly labeled (14C-fatty acid, 3H-glyceryl) chylomicron triglyceride as ...lowered adipose tissue lipoprotein lipase activity from ...mumol ...
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Antibody mediated targeting of the FGFR1c isoform increases glucose uptake in white and brown adipose tissue in male mice
... which tissue(s) contribute to this glucose-lowering ...white adipose tissue (WAT), brown adipose tissue (BAT), the brain, and liver but reduced it in the quadriceps ...decreased ...
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Dietary supplement of Smilax china L. ethanol extract alleviates the lipid accumulation by activating AMPK pathways in high-fat diet fed mice
... AMPK and sterol regulatory element binding proteins (SREBPs) are known to participate in adipogenesis. AMPK is a serine/threonine protein kinase that func- tions as a metabolic master switch [11]. It is expressed in a ...
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Triglyceride deposit cardiomyovasculopathy: a rare cardiovascular disorder
... Triglyceride deposit cardiomyovasculopathy (TGCV) is a phenotype primarily reported in patients carrying genetic mutations in PNPLA2 encoding adipose triglyceride lipase (ATGL) which releases ...
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Recent progress in the study of brown adipose tissue
... roles, adipose tissue in mam- mals is categorized into white adipose tissue (WAT) and brown adipose tissue (BAT) ...of triglyceride (TG)-containing intra- cellular ...
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The effects of pigment epithelium-derived factor on atherosclerosis: putative mechanisms of the process
... ATGL: Adipose triglyceride lipase; ATP: Adenosine triphosphate; BNP: Brain natriuretic peptide; CAD: Coronary artery disease; CVD: Cardiovascular disease; EC: Endothelial cell; ECM: Extracellular ...
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Weight reduction increases adipose tissue lipoprotein lipase responsiveness in obese women
... in adipose tissue, the maintenance of high levels of fasting ATLPL and the increase in enzyme responsiveness in the reduced-obese state could play an important role in the resumption of the obese state, ...
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Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats
... and triglyceride levels in serum, caused a decrease in the weight of adipose tissue and a normalization of serum levels of free fatty acid, GPT, glucose, and uric acid, and a prolongation of ...
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Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer
... the adipose tissue of cancer cach- ectic ...white adipose tissue of cachectic cancer ...into adipose tissue wasting during cancer cachexia progres- sion, we have also analyzed an ...
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Effects of acute hypoxia on human adipose tissue lipoprotein lipase activity and lipolysis
... abdominal adipose tissue biopsies from healthy individuals, we investigated the effects of acute hypoxia on adipose tissue lipid storage and/or mobilization func- ...in adipose ...
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EFFECT OF DIABETES AND INSULIN ON THE ACTIVITY OF MYOCARDIAL AND ADIPOSE TISSUE LIPOPROTEIN LIPASE OF RATS
... Administration of insulin in doses sufficient to control the diabetes restored the lipolytic activity released by heparin from myocardial and epididymal fat tissue to normal Table I.... [r] ...
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Insulin stimulation of adipose tissue lipoprotein lipase Use of the euglycemic clamp technique
... of adipose tissue lipoprotein lipase activity in humans was investigated in 11 normal subjects and compared with the effects of ...basal adipose tissue biopsy for lipoprotein ...
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