Age at Onset
The gene coding for PGC-1α modifies age at onset in Huntington's Disease
... in age at onset of motor symptoms in patients with Huntington's ...the age at onset of HD and hence provide critical support for a role of PGC-1α in the pathogenesis of HD in ...
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New score tests for age at onset linkage analysis in general pedigrees
... Table 1 shows the type I error rates based on 5000 replications and the power based on 1000 simulations, for sample size of 300 families with at least two affected siblings. On simulated data, the proposed methods have ...
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Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset
... early onset and late onset of symptoms in skin ...the age at onset in Huntington disease is ...this age, we noted the age at Huntington disease diagnosis, as well as the ...
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Factors influencing the age at onset in familial frontotemporal lobar dementia
... genetic forms, the clinical expression of the dis- ease can vary from an early occurrence of symp- toms in the third decade of life to a virtually incomplete penetrance in elderly carriers. To date, only TMEM106B has ...
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Age at Onset of Puberty and Adolescent Depression: “Children of 1997” Birth Cohort
... of age at onset of breast/genitalia development with presence of depression varied according to gender (P values for interaction, ...earlier age at onset of breast development was associated ...
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Urinary Tract Infections in Girls: Age at Onset and Urinary Tract Abnormalities
... Urinary Tract Infections in Girls: Age at Onset and Urinary Tract Abnormalities. http://pediatrics.aappublications.org/content/62/2/237[r] ...
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Overlap between age-at-onset and disease-progression determinants in Huntington disease
... participant’s age at that occasion and his/her age at ...used age, which had a near-normal distribution (figure e-5B), as the time variable in our ...Including age as the time indicator also ...
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Familiality and SNP heritability of age at onset and episodicity in major depressive disorder
... early onset (Lin et ...illness onset, suicidality, comorbidities (panic disorder, alcohol and substance abuse), and the quality of social relations (MacKinnon et ...
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Enterococcal Sepsis in Neonates: Features by Age at Onset and Occurrence of Focal Infection
... Among the remaining 56 infants, three groups were apparent: infants with early-onset infection (<7 days of age), infants with late-onset infection (>7 days of age), and infants wit[r] ...
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Genetic analysis of age at onset variation in spinocerebellar ataxia type 2
... The estimate is an upper bound of genetic effects because only first-degree relatives were in the study cohort, and familial similarity, which is used to estimate heritability, includes [r] ...
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Impulsivity in euthymic bipolar disorder patients and relation with age at onset of the disorder
... Method: Fifty-three patients with bipolar disorder were taken to the study. Age and sex matched 52 individuals who had not any history of psychiatric illness lifetime included in the study as a control group. ...
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Biallelic mutation of HSD17B4 induces middle age–onset spinocerebellar ataxia
... infant- onset, RNA expression was significantly lower than that in controls; patients with severe disease exhibited even lower levels of RNA ...infant onset, the proteins were not detected. Even among cases ...
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Sleep Disturbance in Parkinson’s Disease Varies with Age of Onset and Family History
... Genetics may likely influence age of PD onset and therefore may also correlate to PD complications that are associated with age of disease onset. To date, 15 genes and 20 genetic loci relating ...
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A study of the factors affecting the receding age of onset of menarche in young girls
... A majority of girls in our study who attained menarche at an early age had normal BMI. This point to the fact that there could probably be a role of other external factors like endocrine-disruptive chemicals with ...
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Correlation between Severity of Alcohol Dependence with Age of Onset and Family History.
... studied 568 men with a mean age of 47 yrs in a Multicenter study of subjects from Alcoholism treatment centre in America. They used Structured interview (Psychiatric Diagnostic Interview) and trained staff for ...
101
The association between diabetes and age at the onset of menopause: a systematic review protocol
... 3]. Age at the onset of menopause is the most im- portant determinant of women’s future health ...the onset of menopause are still not fully understood, due to a com- plex combination of factors, ...
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Age of Onset of Lactose Malabsorption
... Committee on Nutrition, American Academy of Nutrition: The practical significance of lactose intolerance in children. Pediatrics 62:240, 1978[r] ...
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Age of Alcohol-Dependence Onset: Associations With Severity of Dependence and Seeking Treatment
... early age onset of alcohol dependence, including demo- graphics, personal history of smoking and illicit drug use, family history of alcoholism, childhood antisocial per- sonality disorder, and major ...
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Polymorphisms in the SULF1 gene are associated with early age of onset and survival of ovarian cancer
... the age of disease onset by these genotypes, we found that all five SNPs were more or less associated with age of onset of ovarian ...with age of disease onset (Table 3); the ...
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Comparison of early onset sepsis and community-acquired late onset sepsis in infants less than 3 months of age
... late onset sepsis; CBC, blood cell count; CFR, case fatality rate; CNS, central nervous system; CONS, coagulase negative staphylococcus; CSF, cerebrospinal fluid; EOS, early onset sepsis; ESBL, extended ...
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