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Aging and Longevity

Sex gap in aging and longevity: can sex chromosomes play a role?

Sex gap in aging and longevity: can sex chromosomes play a role?

... Several authors have put forward the importance of sex- ual conflict in the evolution of sex differences in mortal- ity patterns [77] because males and females maximize fitness in very different ways [78, 79]. The ...

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Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a “chi”

Stress responses, vitagenes and hormesis as critical determinants in aging and longevity: Mitochondria as a “chi”

... of aging and determinants of life span will help to reduce age-related morbidity and facilitate healthy ...the longevity network regulates life span across species by coordinating information flow along its ...

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Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

... are longevity assurance processes; importantly, it has been shown that these processes can be controlled by certain dietary and pharmacological interventions known to delay aging in various eukaryotes, ...

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Changes in sleep, non exercise activity thermogenesis and food trends and its effect on aging, health and longevity

Changes in sleep, non exercise activity thermogenesis and food trends and its effect on aging, health and longevity

... Modern day lifestyle trend has been severe cause to many health issues and resulting in cardiovascular diseases, obesity, Endocrine related disease and many others. Today people are adapting healthy lifestyle like ...

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Medaka fish exhibits longevity gender gap, a natural drop in estrogen and telomere shortening during aging: a unique model for studying sex-dependent longevity

Medaka fish exhibits longevity gender gap, a natural drop in estrogen and telomere shortening during aging: a unique model for studying sex-dependent longevity

... and longevity also exist in fish, and (ii) a natural, ‘ menopause ’ -like decline of plasma estrogen was evident in females during ...of aging using ...

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Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells

Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells

... cellular aging. Screens for genetic factors involved in aging typically assay mutants of protein-coding ...cellular aging, we exploited two strains of the fission yeast, Schizosaccharomyces pombe , ...

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Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells

Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells

... cause longevity in nonprolif- erating cells also tend to cause slow growth in proliferating cells (Figure S4; Materials and ...chronological aging, we required an accurate representation of the true ...

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Nuclear–Mitochondrial Epistasis and Drosophila Aging: Introgression of Drosophila simulans mtDNA Modifies Longevity in D. melanogaster Nuclear Backgrounds

Nuclear–Mitochondrial Epistasis and Drosophila Aging: Introgression of Drosophila simulans mtDNA Modifies Longevity in D. melanogaster Nuclear Backgrounds

... and aging, and is determined by the relative levels of oxidant production ...of aging predicts that longevity should be extended by (1) in- creasing the level of ROS defenses, or (2) decreasing the ...

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The Aging Process Deconstructed : Glucose Production, Cancer Resistance and Longevity

The Aging Process Deconstructed : Glucose Production, Cancer Resistance and Longevity

... with aging, such as cancer, stroke, Alzheimer’s and heart disease (Perls, ...the aging process in ...the aging process by reducing the accumulation of oxidative damage (Beckman and BN, ...and ...

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Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes

Recent progress in genetics of aging, senescence and longevity: focusing on cancer-related genes

... on longevity depending on the organism and environmental ...organismal aging, as well as in age-related diseases, Mikhail Blagosklonny has predicted that rapamycin might extend lifespan, by slowing ...

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The matrisome during aging and longevity: a systems-level approach towards

The matrisome during aging and longevity: a systems-level approach towards

... aging, either through collagen fragmentation or loss of adherence proteins [7], cells.. 76.[r] ...

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Longevity of zirconia frameworks

Longevity of zirconia frameworks

... zirconia affecting their longevity (especially aging water environment), and that have not been settled prior to marketing. Despite these problems, it will be difficult to return to metal reinforcements. ...

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Extreme Longevity? He Lives It

Extreme Longevity? He Lives It

... Siegel gave a slide presentation on the “Demography of Retirement in the U.S” to a roomful of actuaries and others on the first morning of the symposium—the seventh in a series that since 2002 has showcased contributions ...

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MEDITERRANEAN DIET: A KEY FOR LONGEVITY

MEDITERRANEAN DIET: A KEY FOR LONGEVITY

... and aging and are involved in the pathogenesis of many degenerative diseases ...premature aging, metabolic syndrome, unipolar depression and the degenerative diseases of the nervous system (3,13,16, ...

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The golden rule of longevity

The golden rule of longevity

... budgetary problems because of the aging of the population. The crowding effects described in this paper would apply both to the rate of return to annuities, retirement schemes and pension funds, which affect the ...

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Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging

Species comparison of liver proteomes reveals links to naked mole-rat longevity and human aging

... and longevity [36], and changes in lipid metabolism have been shown to mediate the positive ef- fects of anti-aging dietary ...accompany aging including a decrease of lean mass and accumulation of ...

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UBS Looks at Longevity and Annuities

UBS Looks at Longevity and Annuities

... addressed longevity risk at all, and that IMCA asked him to speak to its members about it, hints at a growing interest in lifetime income where it once hardly ...

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Longevity hedge effectiveness: A decomposition

Longevity hedge effectiveness: A decomposition

... We use a case study of a pension plan wishing to hedge the longevity risk in its pen- sion liabilities at a future date. The plan has the choice of using either a customised hedge or an index hedge, with the ...

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TRAITS THAT INFLUENCE LONGEVITY IN MICE

TRAITS THAT INFLUENCE LONGEVITY IN MICE

... T h e coat color (b locus) segment of chromosome 4 was associated with life span predominantly in females, whereas the chromosome 17 (H-2 haplotype) segment was assoc[r] ...

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Alzheimer's disease in humans and other animals : a consequence of postreproductive life span and longevity rather than aging

Alzheimer's disease in humans and other animals : a consequence of postreproductive life span and longevity rather than aging

... whereby both arise not as an unfortunate consequence of growing older in the modern world, but are intrinsic to it. In other words that AD and T2DM are conditions not of ageing as they are usually considered, but of ...

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