Aging rats
Mechanisms of Heshouwuyin in regulating apoptosis of testicular cells in aging rats through mitochondrial pathway
... and form superoxide anion in combination with oxy- gen. The superoxide anion turns into reactive oxygen molecules and hydrogen peroxide; however, the two substances are potentially toxic and induce cell apop- tosis. High ...
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Coccomyxa Gloeobotrydiformis Improves Learning and Memory in Intrinsic Aging Rats
... male rats, which have shown significant improvement on learning and spatial memory ability compared with control, which was evidently revealed in both the hidden platform tasks and probe ...aged rats by ...
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Hepatoprotection and neuroprotection induced by low doses of IGF II in aging rats
... old rats; O+IGF-II: aging rats treated with IGF-II; PCC: protein carbonyl content; RH123: rhodamine 123 dye; S: sensitivity; SOD: superoxide dismutase; TAS: total antioxidant status; Yco: young ...
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Acute kidney injury and inflammatory response of sepsis following cecal ligation and puncture in D-galactose-induced aging rats
... This study describes the acute kidney injury and inflamma- tory response of sepsis following cecal ligation and puncture in d -gal-induced aging rats. The results showed that among the three groups the H d ...
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Chronic Administration of the Resveratrol or N PEP 12 Ameliorates the Endothelial Dysfunction in Aging Rats
... in aging rats. Aging rats have shown endothelial ...Sprague-Dawley rats (18 months old) were treated with resveratrol (20 mg/kg/day by gavage) or N-PEP-12 (60 mg/kg/day by ga- vage) for ...
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Original Article rhEPO affects apoptosis in hippocampus of aging rats by upregulating SIRT1
... in rats and on hippocampal neurons was evaluated by utiliz- ing the Morris water maze experiment and Nissl staining of hippocampal CA1 pyramidal neu- rons, respectively, Additionally, the number of hippocampal CA1 ...
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Anti-aging Role of Grape Seed Extract and α-Lipoic Acid in D-Galactose-Induced aging Rats
... induced aging control ...inducing aging effects in hepatic, cardiac and renal functions, contributes to oxidative stress and apoptosis in d-galactose-induced aging ...
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Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat
... AL rats (Fig. 4 B). Moreover, when a subgroup of 18 CR rats was infused with rates of insulin infusion similar to those required in the 18 AL rats, their HGP was significantly decreased and ...
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OXIDATIVE CHANGES AND COGNITIVE FUNCTION DECLINE IN AGING RATS
... Aged rats in our study were seen to be more anxious as indicated by increased excretion of fecal boli and fewer walls supported ...aged rats reduces their anxiety level and increases their exploratory ...
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Original Article Erythropoietin suppresses D-galactose-induced aging of rats via the PI3K/Akt/Nrf2-ARE pathway
... Abstract: EPO (erythropoietin) is a hormone-like substance with a putative role in hematopoietic regulation. Current research suggests that it exerts a neuroprotective effect by enhancing the activity of antioxidant ...
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Effects of early stage aging on locomotor dynamics and hindlimb muscle force production in the rat
... younger rats, there were no discrete differences noted between symmetrical gait dynamics and CoM mechanics, and the symmetrical gaits were dominated by bouncing ...aged rats demonstrated a seemingly random ...
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The Aging Kidney: Increased Susceptibility to Nephrotoxicity
... young rats, renal glutathione (GSH) levels are not decreased in the aging rat kidney ...the aging kidney, but levels are depleted more rapidly when challenged with acute stress ...Wistar rats ...
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Ampelopsin attenuates brain aging of D-gal-induced rats through miR-34a-mediated SIRT1/mTOR signal pathway
... D-gal-induced aging rats using a Takara MiniBEST Universal RNA Extraction Kit (Takara, Dalian, China) and treated with DNase I (Ambion, Austin, TX, USA) to obtain DNA-free RNA according to the ...
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Transcriptome analysis in calorie restricted rats implicates epigenetic and post translational mechanisms in neuroprotection and aging
... CR rats and in LA-fed rats at 28 months when compared with AL rats; this over- lap is reduced to 49 % when including all the dietary varia- tions in our study ...
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Implementation of an active aging model in Mexico for prevention and control of chronic diseases in the elderly
... active aging are health, participation, and security: (i) the prevention and control of chronic diseases, as well as maintaining, prolonging, and recuperating physical, mental, and social functional- ity according ...
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Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats
... IQG (146.0%), and CS10 (184.0%)—treated groups when compared to the control, PBS-treated group. Also, the level of LBP (LPS binding protein) was upregulated in our DNA microarray data, suggesting that heparin (GAG) binds ...
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The effects of aging on muscle loss and tissue specific levels of NF κB and SIRT6 proteins in rats
... of aging on food intake, tissue and organ mass and NF-κB and SIRT6 levels in various ...Sprague-Dawley rats, aged 6 months (Adult) and 21 months (Old) were fed a commercially available diet for 10 - 17 ...
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Sustained density of neuroendocrine cells with aging precedes development of prostatic hyperplasia in spontaneously hypertensive rats
... Sprague-Dawley rats are distributed only in the urethra and the periurethral ducts, which link the urethra and the prostatic lobes, but not in the prostatic ...the rats become older [13]. It is known that ...
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Effects of Guhanyangshengjing Tablet on Testosterone Synthesis and Expression of SYCP3 in the Testis of Aging Male Rats
... SD rats, weighing from 450 to 500 g, were provided by the Animal Center of Sun Yat-sen University (Guangzhou, ...libitum. Rats were randomly allo- cated into four equal groups (n = 10 per group) and ...
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Perceptions towards aging among selected Filipino adults
... Almost all the participants revealed that they were excited or eager to be an adult when they were still a child because of various reasons such as being allowed to wear adults’ clothes or have a developed body. They ...
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