airway inflammation
Pentraxin 3 promotes airway inflammation in experimental asthma
... established. Immunization of mice with OVA/LPS has been reported to cause neutrophilic airway inflamma- tion, in contrast to the eosinophilic airway inflammation provoked by OVA/Alum [20]. We ...
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Role and regulation of MKP-1 in airway inflammation
... network in ASM cells and confirmed that precise tem- poral signalling is necessary to exert TTP-dependent anti- inflammatory control of cytokines implicated in respira- tory disease. In brief, we have shown that TTP ...
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Airway inflammation and mannitol challenge test in COPD
... release of mediators in the airways [7]. In particular, this holds for indirect challenges, amongst which dry powder mannitol challenge is relatively easy to apply [8,9]. Local mannitol deposition results in an osmotic ...
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P2rx4 deficiency in mice alleviates allergen-induced airway inflammation
... in airway inflammation has not been elucidated ...allergen-induced airway inflammation ...peribronchial inflammation, Th2 cytokine production and bronchial ...
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Pathogenesis of persistent lymphatic vessel hyperplasia in chronic airway inflammation
... The present study revealed that airway inflammation is accom- panied not only by angiogenesis but also by extensive growth of lymphatic vessels. In mice with M. pulmonis infection, lymphangio- genesis ...
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Exposure to volatile organic compounds and airway inflammation
... new house and point to the new indoor environment as a trigger of their symptoms. Actually, several studies have linked VOC exposure to asthma and other respira- tory symptoms, although there is no consistent associ- ...
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A pathophysiological role of PDE3 in allergic airway inflammation
... PDE3 inhibition and the expression of CD11b. Given the fast antiallergic response, we investigated whether PDE3 effects on integrin might be associated in allergic airway inflammation. Mouse and human ...
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Clinical update on the use of biomarkers of airway inflammation in the management of asthma
... Abstract: Biological markers are already used in the diagnosis and treatment of cardiovascular disease and cancer. Biomarkers have great potential use in the clinic as a noninvasive means to make more accurate diagnoses, ...
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A qPCR-based metric of Th2 airway inflammation in asthma
... Th2 airway inflammation using RNA derived from epi- thelial brushings, which we term the ...Th2 inflammation as significantly associated with AHR in human ...Th2 inflammation in human asthma ...
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Real time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation
... allergic airway inflammation and an important clinical therapeutic ...allergic airway inflammation and identified a viridin-derived prodrug that potently inhibited the accumula- tion and ...
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PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse
... In mice, airway inflammation induced by LPS is associ- ated with an increase of the matrix metalloproteinases (MMP), MMP-2 and MMP-9 [7,8]. MMP are a family of zinc- and calcium-dependent endopeptidases ...
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Role of eosinophils in airway inflammation of chronic obstructive pulmonary disease
... agonist, regular anticholinergic, LABA, LAMA, theophylline, and then a trial with a nebulizer; inhaled corticosteroids continued at the same dosage if the patient was already receiving them. For patients in the optimize ...
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Eosinophilic airway inflammation in COPD
... eosinophilic airway inflammation is usually considered a feature of asthma, it has been demonstrated in large and small airway tissue samples and in 20%–40% of induced sputum samples from patients ...
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Endotoxin Is Not Essential for the Development of Cockroach Induced Allergic Airway Inflammation
... and airway inflammation characterized by Th2 effector cell and eosinophil ...the airway following allergen exposure as a result of the development of this ...
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The R213G polymorphism in SOD3 protects against allergic airway inflammation
... increased airway EC-SOD attenuates allergic airway inflammation are consistent with other published studies suggesting that EC-SOD attenuates lung oxidative stress–mediated lung injury from LPS, ...
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Occupational exposures, smoking and airway inflammation in refractory asthma
... Motor exhaust fumes were the most common expos- ure identified from the participants’ occupation analysis. This may represent a common exposure in adults with neutrophilic bronchitis as exposure to diesel exhaust can ...
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Airways Disease: Phenotyping Heterogeneity Using Measures of Airway Inflammation
... of airway disease based on the pattern of airway inflammation may be particularly useful in increasing our understanding of the ...of airway inflammation has suggested the presence of ...
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Allergic airway inflammation induces the migration of dendritic cells into airway sensory ganglia
... Results: Immune cells with characteristic DC-phenotype were found to be closely located to SGCs and vagal sensory neurons under physiological conditions. The percentage of DCs in relation to neurons was significantly ...
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Role of C5 in the development of airway inflammation, airway hyperresponsiveness, and ongoing airway response
... of airway inflammation, (b) the maintenance of airway hyperresponsiveness (AHR), and (c) sustainment of an ongoing airway response to allergen ...established airway inflammation ...
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Zinc supplementation alters airway inflammation and airway hyperresponsiveness to a common allergen
... decreased inflammation due to decreased NF- B activ- ...allergic airway inflammation in our established mouse ...an airway response by sen- sitizing and challenging mice to GC frass on days 0, ...
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