Airway remodeling
Original Article Mesenchymal stem cells suppress lung inflammation and airway remodeling in chronic asthma rat model via PI3K/Akt signaling pathway
... way remodeling could be through a PI3K/Akt ...accumulation, airway remodeling and also ...treating airway remodeling and inflammation in asthma through induction of the production of ...
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Link between vitamin D and airway remodeling
... treatment concomitant with ovalbumin challenge reduced chronic ovalbumin-induced inflammation and attenuated structural changes in the airways, including subepithelial fibrosis, goblet cell hyperplasia, and increased ASM ...
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Inhibition of airway remodeling and inflammatory response by Icariin in asthma
... anti-airway remodeling, few studies have demonstrated the efficacy of ICA in the experimental model of asthma, not to mention the possibility of resistance to ...
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Inhibition of airway remodeling in IL 5–deficient mice
... induced airway remodeling to demonstrate that IL-5 plays an important role in airway remodeling as evi- denced by reduction in two of the cardinal structural features associated with ...
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Original Article KyoT2 downregulates airway remodeling in asthma
... are airway remodeling and airway hyperresponsiveness ...of airway remodeling or the modulation of airway resistance in asthma is ...asthma-associated airway ...
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Roles of Bronchopulmonary C-fibers in airway Hyperresponsiveness and airway remodeling induced by house dust mite
... pulmonary remodeling, and the RSV-induced ...pulmonary remodeling characterized by collagen and elastic fiber deposition in airways [11] in ovalbumin-induced asthma ...of airway con- striction, ...
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Prolonged ozone exposure in an allergic airway disease model: Adaptation of airway responsiveness and airway remodeling
... induces airway inflammation in dogs [3], guinea pigs [4], and humans ...Chronic airway inflammation is associated with airway remodeling that includes airway wall thickening as a result ...
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Airway hyperresponsiveness is associated with airway remodeling but not inflammation in aging Cav1-/-mice
... airway remodeling. Our data are supportive of the beneficial effects on airway remod- eling after treatment with Cav1 scaffolding domain pep- ...established airway remodeling and AHR ...
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A role for airway remodeling during respiratory syncytial virus infection
... in atopic individuals. In fact, our studies demonstrated that interactions between RSV infection and allergen- induced immune responses exacerbate pulmonary inflammation and airway physiology. Furthermore, the ...
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Small airway remodeling in acute respiratory distress syndrome: a study in autopsy lung tissue
... that remodeling is also present at the terminal bronchiolar level and suggest that these structural air- way changes may also have functional ...of airway remodeling are dependent on which layer in ...
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Original Article The increased expression of β2ARs depresses airway remodeling in children with bronchial asthma
... by airway hyperresponsiveness (AHR) ...incomplete airway repair and eventually lead to airway remodeling ...of airway remodeling and its drug therapy is not very ...children. ...
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A HuR/TGF-β1 feedback circuit regulates airway remodeling in airway smooth muscle cells
... HuR, the sole ubiquitous member of the Hu RNA- binding protein family, can bind to a subset of short- lived mRNAs that harbor AU-rich elements (AREs) in their 3′ untranslated regions (UTR), which is called ...
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Role of TRPC1 channels in pressure-mediated activation of airway remodeling
... increased airway wall thick- nesses, abnormal collagen deposition below sub-epithelial layer, smooth muscle hyperplasia and ...impaired airway remodeling in asthmatic ...impaired airway remod- ...
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Chronic asthma and Mesenchymal stem cells: Hyaluronan and airway remodeling
... Airway remodeling, as seen in chronic asthma, in- cludes epithelial detachment, subepithelial fibrosis, in- creased smooth muscle mass, goblet cell hyperplasia, proliferation of blood vessels, and ...for ...
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Mechanism of Yanghe Pingchuan granules treatment for airway remodeling in asthma
... of airway remodeling, and is a potential target for ...affects airway remodel- ing through inhibiting the expression of the PI3K signaling ...cause airway remodeling, and that ...
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Role of inflammatory cells in airway remodeling in COPD
... of airway remodeling and how remodeling contributes to the decrease in lung func- ...on airway remodeling in COPD pathogenesis, it is imperative to explore the mecha- nisms of ...
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Airway remodeling in asthma
... induce airway remodeling are not well ...and remodeling, with chronic inflammation inducing remodeling responses in some settings but not in ...remodeled airway, it has received the ...
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Effect of aging on airway remodeling and muscarinic receptors in a murine acute asthma model
... the airway during development of acute asthma differed between young and older ...of airway remodeling in lung tissue, compared with young ...
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Exchange protein directly activated by cAMP (Epac) protects against airway inflammation and airway remodeling in asthmatic mice
... in airway smooth muscle relaxation [13], proliferation [7], phenotype change [10, 19] and cytokines secretion [7], and also fibroblasts proliferation [20], suggesting a possible role of Epac in airway ...
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Role of Abl in airway hyperresponsiveness and airway remodeling
... measure airway resistance, mice were anesthetized with an intraperitoneal injection of pen- tobarbital sodium, tracheotomized, and connected to the FlexiVent system (SCIREQ, Montreal, Canada) on Day ...
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