alpha 2 (I) collagen
A substitution at a non glycine position in the triple helical domain of pro alpha 2(I) collagen chains present in an individual with a variant of the Marfan syndrome
... pro alpha 2(I) collagen molecule was found in an individual with a variant of the Marfan ...pro alpha 2(I) chains of type I collagen synthesized by dermal ...
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Abnormal alpha 2 chain in type I collagen from a patient with a form of osteogenesis imperfecta
... pro alpha-chain, the alpha-chain, and of the mammalian collagenase cleavage products of the pro alpha- and alpha-chains indicates that the abnormality is confined to the alpha ...
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Osteogenesis imperfecta type IV Biochemical confirmation of genetic linkage to the pro alpha 2(I) gene of type I collagen
... pro alpha 2(I) gene of type I collagen synthesize two populations of pro alpha 2(I) ...pro alpha 2(I) causes increased posttranslational ...
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Diminished type I collagen synthesis and reduced alpha 1(I) collagen messenger RNA in cultured fibroblasts from patients with dominantly inherited (type I) osteogenesis imperfecta
... Type I osteogenesis imperfecta (OI) is characterized clinically by a moderate fracture frequency with minimal bone deformity and dominant ...elevated alpha 1(III) to alpha 1(I) collagen ...
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Mithramycin selectively inhibits collagen alpha 1(I) gene expression in human fibroblast
... the collagen-alpha 1(I) and -alpha 2(I) genes form the triple helical molecule collagen type I, which constitutes the major ECM protein in tissue ...The ...
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Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction
... five collagen genes (type I collagen, alpha 2 chain [COL1A2], type II collagen alpha 1 chain [COL2A1], type III collagen alpha 1 chain [COL3A1], type V ...
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Analysis of normal and osteoarthritic canine cartilage mRNA expression by quantitative polymerase chain reaction
... five collagen genes (type I collagen, alpha 2 chain [COL1A2], type II collagen alpha 1 chain [COL2A1], type III collagen alpha 1 chain [COL3A1], type V ...
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Amino Acids Sequences Analysis on Collagen
... The alpha 1 (α1) and alpha 2 (α2) chains of collagen type I (CTI) of five species were collected from the Nat. Center for Biotechnology Information [ http://www.ncbi.nlm.nih.gov/] and ...
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New insights into the pathogenesis of glucocorticoid induced avascular necrosis: microarray analysis of gene expression in a rat model
... A2M: alpha-2-macroglobulin; ANFH: avascular necrosis of the femoral head; BMP-1: bone morphogenic protein-1; Col2A1: collagen type II alpha-1; ΔCt: comparative threshold cycle; DAB: ...
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<p>The Biological Role of the Collagen Alpha-3 (VI) Chain and Its Cleaved C5 Domain Fragment Endotrophin in Cancer</p>
... The collagen alpha-3 (VI) chain is widely expressed in var- ious cancer cell lines and ...produce collagen alpha-3 (VI) chain in tumors have not been well characterized, COL6A3 gene expression ...
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Frameshift mutation near the 3' end of the COL1A1 gene of type I collagen predicts an elongated Pro alpha 1(I) chain and results in osteogenesis imperfecta type I
... type I collagen of which OI type I, an autosomal dominant condition, is the mildest and most common ...type I collagen as a result of decreased synthesis of one of its constituent ...
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Effect of coculturing canine notochordal, nucleus pulposus and mesenchymal stromal cells for intervertebral disc regeneration
... Complete spines (cervical, thoracic and lumbosacral regions) were collected from four mongrel dogs (non- chondrodystrophic (NCD1 through NCD4); female, age 1.3 ± 0.5 years, weight 26.0 ± 14.6 kg (mean ± standard de- ...
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Clonorchis sinensis lysophospholipase A upregulates IL 25 expression in macrophages as a potential pathway to liver fibrosis
... and Collagen-I, and migrate to sites of damage [19, ...increases collagen secretion by normal human lung fibroblasts ...and Collagen-I and promoted the migration of LX-2 ...
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Role of alpha adrenoceptors in opossum internal anal sphincter
... that alpha- 2 adrenoceptors exert important neuromodulatory influences on rectoanal inhibitory reflex, while alpha-1 adrenoceptors may exert modulatory effects on the resting IAS ...
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Orbital dermatofibrosarcoma protuberans with intracranial extension preceded by recurrent leiomyoma of the orbit: a case report
... CT of the brain demonstrated mild white matter ische- mic changes, and CT of the orbit showed a well-defined, lobulated soft tissue mass along the superomedial aspect of the orbit measuring 5.3×4.8cm and extending 4.3cm ...
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Intra articular injection of synthetic microRNA 210 accelerates avascular meniscal healing in rat medial meniscal injured model
... Several groups have reported recently that miR-210 is a key player in angiogenesis in response hypoxia [25,26]. Overexpression of miR-210 has also been reported to stimulate the formation of capillary-like structures in ...
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Polymorphism of a COLIA1 Gene Sp1 Binding Site in Korean Women with Pelvic Organ Prolapse
... Recent studies indicate that a polymorphism of the gene encoding the type I collagen alpha-1 chain COLIA1 gene may affect the development of osteoporosis and stress urinary incontinence,[r] ...
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LAP (NF IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region
... transcription in both orientations and when placed in front of either a homologous or a heterologous chimeric report construct. These experiments suggest that LAP may be important in the expression of collagen in ...
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Effect of Phase I Therapy on Salivary Carboxyterminal Telopetide of Type I Collagen in Chronic Periodontitis Patients
... type I collagen degradation products in serum (S-ELISA) with an isomerised form of an eight amino acid ...type I collagen. He reported that Asp-Gly site present in type I ...
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Antifibrotic Effects of Limbal Mesenchymal Stem Cells-Conditioned Media (LMSCs-CM) on Human Tenon’s Fibroblasts (HTFs) in Glaucomatous Eyes: Comparison with Mitomycin C
... HTFs were seeded into wells of six-well culture dishes and allowed to attach and grow to confluence. The cells were then scratched wounded by a pipette tip and washed with medium to remove loose or dead cells. Treatment ...
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