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Alveolar damage

Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage

Local abnormalities of coagulation and fibrinolytic pathways that promote alveolar fibrin deposition in the lungs of baboons with diffuse alveolar damage

... Because alveolar fibrin is a prominent histologic feature of diffuse lung injury in baboons, we hypothesized that local abnormalities of pathways of fibrin turnover would favor fibrin deposition in the ...

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Bronchoalveolar lavage cytological alveolar damage in patients with severe pneumonia

Bronchoalveolar lavage cytological alveolar damage in patients with severe pneumonia

... epithelial damage, edema, hemorrhage, the intra-alveolar accumulation of polymorphonuclear neutrophils and hyaline membrane ...active alveolar hemorrhage [9]. Furthermore, damage at the ...

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Case Report Diffuse alveolar damage in a patient with Epstein Barr virus (EBV)-positive diffuse large B-cell lymphoma, severely low serum folate, and megaloblastic anemia: a case report of autopsy

Case Report Diffuse alveolar damage in a patient with Epstein Barr virus (EBV)-positive diffuse large B-cell lymphoma, severely low serum folate, and megaloblastic anemia: a case report of autopsy

... Diffuse alveolar damage (DAD) is a histopatho- logical correlate of acute respiratory distress syndrome characterized by rapidly progressing dyspnea. One of the histopathological hall- marks for DAD is a ...

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Comparison of four pharmacological strategies aimed to prevent the lung inflammation and paraquat induced alveolar damage

Comparison of four pharmacological strategies aimed to prevent the lung inflammation and paraquat induced alveolar damage

... Methods: 54 Wistar SPF rats were used. After 2 h post-intoxication with paraquat ion, groups of 9 animals were ran- domly assigned to (1) cyclophosphamide plus dexamethasone (2) low molecular weight heparin (3) ...

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Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage

Lymphatic impairment leads to pulmonary tertiary lymphoid organ formation and alveolar damage

... which alveolar development is nearly complete (52). The emphysematous alveolar phenotype in plt-Clec2–KO mice was associated with hypoxia, an indicator of significant impairment of lung function (Figure ...

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Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome

Acute Interstitial Pneumonia (Hamman-Rich Syndrome) as a Cause of Idiopathic Acute Respiratory Distress Syndrome

... diffuse alveolar damage pattern- mixed exudative and organizing phase, as demonstrated by video- assisted thoracostomy lung biopsy: showing interstitial edema and hemorrhage (A), diffuse alveolar wall ...

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Histomorphological Lung Changes and Cause of Death Correlation: An Autopsy Based Study in a Tertiary Care Centre

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... inflammation, alveolar collapse and/or thinning, alveolar wall disturbances, Diffuse Alveolar Damage (DAD), capillary dilatation, haemosiderotic changes, anthracotic changes, bronchial ...

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Protective effects of chebulic acid on alveolar epithelial damage induced by urban particulate matter

Protective effects of chebulic acid on alveolar epithelial damage induced by urban particulate matter

... and alveolar macrophages secreted cytokine and chemo- ...of alveolar macrophage against UPM lead to acute lung injury and chronic obstructive pulmonary disease [35, ...against alveolar damage ...

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Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

Acute exacerbation of idiopathic pulmonary fibrosis: lessons learned from acute respiratory distress syndrome?

... diffuse alveolar damage (DAD) superimposed on the usual interstitial pneumonia (UIP) pattern ...and alveolar epithelial injury and cellular exudate and hyaline membrane de- position develops during ...

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Are risk predicting models useful for estimating survival of patients with rheumatoid arthritis-associated interstitial lung disease?

Are risk predicting models useful for estimating survival of patients with rheumatoid arthritis-associated interstitial lung disease?

... Diffuse alveolar damage; DLCO: Diffusion capacity to carbon monoxide; FEV1: Forced expiratory volume; FVC: Forced vital capacity; GAP: Gender, age and physiological variables; HR: Hazard ratio; HRCT: ...

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Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS

Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS

... diffuse alveolar damage ...diffuse alveolar damage (DAD) in histopathology, and LIS and driving pressures in the last 2 days before ...

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Disruption of staphylococcal aggregation protects against lethal lung injury

Disruption of staphylococcal aggregation protects against lethal lung injury

... creating alveolar concavities that accumulate localized pools of alveolar liquid ...at alveolar curvatures as infection ...of alveolar curvatures, as perhaps in ...or alveolar micro- ...

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Clinical review: Idiopathic pulmonary fibrosis acute exacerbations   unravelling Ariadne's thread

Clinical review: Idiopathic pulmonary fibrosis acute exacerbations unravelling Ariadne's thread

... use alveolar damage (DAD), which is the tissue counterpart of ARDS, upon usual interstitial pneumonia, which is the tissue equivalent of ...tissue damage pattern of ...

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A case of herbicide-induced acute fibrinous and organizing pneumonia?

A case of herbicide-induced acute fibrinous and organizing pneumonia?

... diffuse alveolar damage (DAD) [5, ...the alveolar spaces, rather than the fibrous tissue and fibroblast proliferation seen in OP; the numerous eosinophils, macrophage infiltration and eosinophil ...

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Acute exacerbation of IPF has systemic consequences with multiple organ injury, with SRA+ and TNF-α+ cells in the systemic circulation playing central roles in multiple organ injury

Acute exacerbation of IPF has systemic consequences with multiple organ injury, with SRA+ and TNF-α+ cells in the systemic circulation playing central roles in multiple organ injury

... Results: The median age at autopsy was 68 years (range 45 – 87 years); 11 subjects (78.5 %) were men. High-dose corticosteroid, cyclophosphamide and oxygen therapy had been administered to all patients. Underlying ...

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Augmenting autophagy for prognosis based intervention of COPD-pathophysiology

Augmenting autophagy for prognosis based intervention of COPD-pathophysiology

... the alveolar damage that mediates the emphysema progression and severe lung function decline is apparent, although the central mechanism that regulates these processes was ...reduce alveolar ...

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Vol 70, No 4 (2018)

Vol 70, No 4 (2018)

... additional damage to the lung tissue through the release of multiple toxic mediators, including proteases, ROS and proinflammatory cytokines, all of which exacerbate ALI ...and alveolar-capillary barrier ...

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Alveolar macrophage functions and DNA damage  in cigarette smoke exposed mice

Alveolar macrophage functions and DNA damage in cigarette smoke exposed mice

... Alveolar macrophages (AM) are known to play an essential role in lung defense through their ability to remove the foreign matters reaching the lung alveoli. Cigarette smoke (CS) is a critical risk factor for many ...

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Key words

Key words

... rhage, alveolar edema, congestion and leukocyte infiltration. Intra-alveolar hemorrhage, alveolar edema and congestion were scored on a scale from 0 to 3 where 0 = absence of pathology (< 5% of ...

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Nerve Injuries During Root Canal Treatment: A Review

Nerve Injuries During Root Canal Treatment: A Review

... This review reveals the need to exercise great care in all steps of root canal treatment of nonsurgical endodontic therapy, especially when the root apices are in close proximity to vital anatomic structures such as the ...

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