alveolar epithelial type II cells
Culture of human alveolar epithelial type II cells by sprouting
... lung alveolar epithelium comprises two types of specialized epithelial cells, the alveolar epithelial type I cells (AT1), that cover approximately 93% of the ...
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Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung
... A549 cells upon hyperoxia exposure in a dose-dependent manner ...primary alveolar epithelial Type II cells led to increased sensitivity to TGFβ-induced apoptosis ...
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Original Article Hyperbaric oxygen treatment reduced the lung injury of type II decompression sickness
... lar epithelial cells were slightly swollen, and although bubbles were present, they were small in number and volume and were only partly present in blood ...of alveolar spaces and obvious embolism of ...
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
... and cells incubated with 50 μl of primary antibodies diluted in 1× Rotiblock over-night at 4 ...and cells washed three times with 150 μl of ...the cells were washed three times with 150 μl PBS and ...
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Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
... lung epithelial cells during HDM ...of epithelial cells downstream of ATF6 during HDM chal- ...lung epithelial cell specific ablation of ERp57 and/or ATF6α to determine the role of ...
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Case Report Primary pleomorphic adenoma of the lung with positive staining of TTF-1: a case report and review of literature
... tumor epithelial cells were po- sitive for TTF-1 ...thyroid epithelial ce- lls. The salivary gland-type tumors of the lung, including pleomorphic adenoma, were origi- nated from the bronchial ...
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TGF beta 1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
... human type II alveolar epithelial cells because cultures of these cells rapidly adopt fibroblast-like morphology, even in the absence of ...A549 cells to TGF-β1 are unique ...
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Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo
... of type II alveolar epithelial cells in the lungs of adult ...active alveolar cells histologically appears as a micropapillary epithelial cell hyperplasia after 2 d ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... adenocarcinoma alveolar epithelial cell line; ATII: primary human alveolar type-II epithelial cells; BALB-3 T3: mouse embryonic fibroblast cell line; BEAS-2B: human ...
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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
... in alveolar macrophages and lung tissue homogenate but not in type II alveolar epithelial cells both under baseline conditions and in response to bleomycin was noted, suggesting ...
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Alveolar Type II Epithelial Cells Contribute to the Anti Influenza A Virus Response in the Lung by Integrating Pathogen and Microenvironment Derived Signals
... are type II alveolar epithelial cells (AECII), which are increasingly recognized for their immunological ...in cells sorted from the lungs of infected ...
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Alveolar type II epithelial cells produce interleukin 6 in vitro and in vivo Regulation by alveolar macrophage secretory products
... Induction was abolished when CM were preincubated with anti-IL-1 beta and anti-TNF alpha antibody. The combination of IFN gamma and LPS induced the expression of IL-6 mRNA by A549 cells whereas LPS alone had no ...
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Thymoquinone (TQ) inhibits the replication of intracellular Mycobacterium tuberculosis in macrophages and modulates nitric oxide production
... Human type II alveolar epithelial cells; ADC: Albumin-dextrose- catalase; ATCC: American Type Culture Collection; CFU: Colony forming unit; DMEM: Dulbecco ’ s Modified Eagle ’ s ...
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The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells
... abnormal alveolar capillary network and decreased expression of endothelial cell markers have been found in premature newborns dying with BPD ...cultured type II lung epi- thelial cells, (as ...
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Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.
... 2011). Alveolar epithelial cells are divided into type I and type II ...stem cells and have the potential to give rise to the former. Moreover, type II ...
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Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
... AT-II cells already demonstrated that AT-II cells can differentiate into AT-I cells ...AT-I cells after pneumonectomy has been ...AT-I cells proliferate and differentiate ...
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Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo
... endothelial cells (HCAECs) were exposed to ZnO-NPs in either monoculture or coculture with human alveolar type II epithelial cells (A549), then levels of interleukin-8 (IL-8), ...
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Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells
... alert cells [12, 25], these cells also increase in number due to SIRS complica- tion or sustained ...Alert cells express inflam- matory receptors on their surface and in their cytoplasm and are ...
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Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation
... ATII cells from free cholesterol-induced cyto- toxicity by exporting free ...cholesterol. Cells transfected with a non-functional mutant of ABCA3, ABCA3- Q215K, displayed excessive accumulation of ...
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The cellular kinetics of lung alveolar epithelial cells and its relationship with lung tissue repair after acute lung injury
... Tissue or cells were lysed in lysis buffer (10 mM Tris- HCl, pH 7.5, 1% Triton X-100, 1 mM EDTA, and 1 mM phenylmethylsulfonyl fluoride, 10 g/ml aprotonin, and 10 g/ml leupeptin). The protein concentration was de- ...
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