Alveolar type II cell
Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441
... ATII-like cell lines A549 and NCIH441 were seeded on fibronectin-coated Thermanox cover slips (NUNC – Thermo Fisher Scientific, Germany) and culti- vated until ...both cell incubation conditions, after 3 hr ...
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Interleukin 10 Down Regulates Cathepsin B Expression in Fetal Rat Alveolar Type II Cells Exposed to Hyperoxia
... fetal alveolar type II cell (FATI- IC) death and pretreatment of recombinant IL-10 (rIL-10) attenuates type II cell death during ...rat alveolar type ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... epithelial cell line; AM: alveolar macrophages; AO: adverse outcome; AOP: adverse outcome pathway; ATII: primary human alveolar type-II epithelial cells; BEAS-2B: bronchial epithelial ...
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Metabolism of platelet activating factor in isolated perfused rat lung
... metabolism into lyso-PAF (3.3%), phosphatidylcholine (82.3%), neutral lipid (1.7%) and intact PAF (10.2%). Analysis of tissue phosphatidylcholine by mass spectrometric techniques revealed metabolism of PAF to ...
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Human mast cells decrease SLPI levels in type II – like alveolar cell model, in vitro
... under cell co-culture conditions SLPI levels in cell culture media are gradually decreased, although the expression of mRNA SLPI ...of cell co-cul- ture, although the SLPI mRNA was up-regulated (by ...
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Endothelial-monocyte activating polypeptide II disrupts alveolar epithelial type II to type I cell transdifferentiation
... total cell number was calcu- lated using DAPI (nuclear) counting in the same field and the positive TUNEL or Ki67 cells were reported as percent of cells ...
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Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate
... The alveolar diameters were decreased and septal thicknesses increased relative to control lungs (Additional file ...cells, alveolar epithelial type II cells, and alveolar epithelial ...
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Exosome miR-371b-5p promotes proliferation of lung alveolar progenitor type II cells by using PTEN to orchestrate the PI3K/Akt signaling
... stem cell-derived mature ATIIC ...SPC-expressing cell population (41%), yet only approxi- mately 15% of cells in hESC-derived cultures in DM expressed SPC on day 16 ...A549 cell-derived signaling, ...
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Alveolar Type II Epithelial Cells Contribute to the Anti Influenza A Virus Response in the Lung by Integrating Pathogen and Microenvironment Derived Signals
... are type II alveolar epithelial cells (AECII), which are increasingly recognized for their immunological ...immune cell recruitment, and antigen ...and cell recruitment indicated AECII ...
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Double impact of cigarette smoke and mechanical ventilation on the alveolar epithelial type II cell
... from alveolar lavage compared to blood macro- phages is relatively limited [44] and that acute cigarette smoke exposure can induce apoptosis of alveolar macro- phages ...in alveolar epithelial ...
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Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung
... as cell death in A549 cells upon hyperoxia exposure in a dose-dependent manner ...primary alveolar epithelial Type II cells led to increased sensitivity to TGFβ-induced apoptosis ...
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Original Article Hyperbaric oxygen treatment reduced the lung injury of type II decompression sickness
... with type II decompression sickness (DCS), and study the therapeutic effects of hyperbaric oxygen ...the alveolar space. Type I alveolar epithelial cells exhibited retracted cell ...
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LysoTracker is a marker of differentiated alveolar type II cells
... airway, alveolar or mixed lineage epi- thelial cells in our CFU-Epi assay which can be identified by their distinct morphologies ...progenitor cell colonies ...by alveolar and mixed lineage ...
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Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization
... 1-null type II alveolar epithelial cells are increased in number and morphologically abnormal with enlarged nuclei and fewer mitochondria and lamellar bodies, suggesting abnormal type ...
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Alveolar epithelial type II cell: defender of the alveolus revisited
... of alveolar surface as a continuous, thin ...total alveolar surface despite the use of lipid-stabilis- ing tissue processing ...total alveolar surface is still lacking, this is a reasonable and ...
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Immunoreactive apolipoprotein E is a widely distributed cellular protein Immunohistochemical localization of apolipoprotein E in baboon tissues
... following cell types have been found to harbor apoE immunoreactivity: cerebral astrocytes; thyroid follicular cells; alveolar type II pneumocytes; hepatocytes, and Kupffer cells; ...
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Phenotypic alterations in type II alveolar epithelial cells in CD4+ T cell mediated lung inflammation
... AEC II were prepared using a modified protocol of a previously published method ...Crude cell suspensions were sequentially filtered through nylon gauze (100 μm, 45 μm, 30 μm) followed by centrif- ugation ...
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Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.
... I alveolar epithelial cells cover more than 95% of the alveolar surface, and are vulnerable to various ...from type II alveolar cells, the involvement of which in lung injury has been ...
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PlGF mediates neutrophil elastase-induced airway epithelial cell apoptosis and emphysema
... Apoptosis of LE cells results in the loss of lung paren- chyma and is a potential pathogenic mechanism for em- physema and COPD [21]. Placenta growth factor (PlGF) induces apoptosis of type II ...
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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
... in alveolar macrophages and lung tissue homogenate but not in type II alveolar epithelial cells both under baseline conditions and in response to bleomycin was noted, suggesting that ...
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