Alveolar type II epithelial cells
Alveolar Type II Epithelial Cells Contribute to the Anti Influenza A Virus Response in the Lung by Integrating Pathogen and Microenvironment Derived Signals
... their epithelial expression was highlighted by the finding that fold change induction in AECII often exceeded that in lung ...dendritic cells (pDC) was reported to lead to a significantly diminished IFN I ...
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Alveolar type II epithelial cells produce interleukin 6 in vitro and in vivo Regulation by alveolar macrophage secretory products
... these cells, and (c) to detect the in vivo expression of immunoreactive IL-6 by human ATII ...ATII cells in primary culture secreted bioactive IL-6 and immunostained with an anti-IL-6 ...ATII cells ...
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Mechanisms of lung fibrosis induced by carbon nanotubes: towards an Adverse Outcome Pathway (AOP)
... adenocarcinoma epithelial cell line; AM: alveolar macrophages; AO: adverse outcome; AOP: adverse outcome pathway; ATII: primary human alveolar type-II epithelial cells; ...
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Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
... lung epithelial cells during HDM ...of epithelial cells downstream of ATF6 during HDM chal- ...lung epithelial cell specific ablation of ERp57 and/or ATF6α to determine the role of ...
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Zinc oxide nanoparticle-induced atherosclerotic alterations in vitro and in vivo
... endothelial cells (HCAECs) were exposed to ZnO-NPs in either monoculture or coculture with human alveolar type II epithelial cells (A549), then levels of interleukin-8 (IL-8), ...
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Case Report Primary pleomorphic adenoma of the lung with positive staining of TTF-1: a case report and review of literature
... of epithelial and myxoid-chondroid mesenchymal ...the epithelial cells of this tumor were positive for thyroid transcription factor-1 (TTF-1) staining, which indicated its dif- ferentiation toward ...
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Human alveolar epithelial cells type II are capable of TGFβ-dependent epithelial-mesenchymal-transition and collagen-synthesis
... of cells during EMT [12, 15, 22], was assessed on protein level to validate the results from the gene expression arrays in cells from independent pa- ...A549 cells [15], strong actin signal was ...
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Culture of human alveolar epithelial type II cells by sprouting
... lung alveolar epithelium comprises two types of specialized epithelial cells, the alveolar epithelial type I cells (AT1), that cover approximately 93% of the ...
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TGF beta 1 induces human alveolar epithelial to mesenchymal cell transition (EMT)
... human type II alveolar epithelial cells because cultures of these cells rapidly adopt fibroblast-like morphology, even in the absence of ...A549 cells to TGF-β1 are unique ...
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Original Article Hyperbaric oxygen treatment reduced the lung injury of type II decompression sickness
... lar epithelial cells were slightly swollen, and although bubbles were present, they were small in number and volume and were only partly present in blood ...of alveolar spaces and obvious embolism of ...
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Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo
... of type II alveolar epithelial cells in the lungs of adult ...active alveolar cells histologically appears as a micropapillary epithelial cell hyperplasia after 2 d ...
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Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung
... A549 cells upon hyperoxia exposure in a dose-dependent manner ...primary alveolar epithelial Type II cells led to increased sensitivity to TGFβ-induced apoptosis ...
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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis
... in alveolar macrophages and lung tissue homogenate but not in type II alveolar epithelial cells both under baseline conditions and in response to bleomycin was noted, suggesting ...
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The angiogenic factor midkine is regulated by dexamethasone and retinoic acid during alveolarization and in alveolar epithelial cells
... Prolonged treatment with high doses of GC was widely used in immature infants with evolving bronchopulmo- nary dysplasia (BPD) during the 1990s. These treatments were based on the belief that such treatment was associ- ...
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Thymoquinone (TQ) inhibits the replication of intracellular Mycobacterium tuberculosis in macrophages and modulates nitric oxide production
... Human type II alveolar epithelial cells; ADC: Albumin-dextrose- catalase; ATCC: American Type Culture Collection; CFU: Colony forming unit; DMEM: Dulbecco ’ s Modified Eagle ’ s ...
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Mac-1 deficiency induces respiratory failure by affecting type I alveolar epithelial cells.
... 2011). Alveolar epithelial cells are divided into type I and type II ...stem cells and have the potential to give rise to the former. Moreover, type II ...
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Regeneration of the lung: Lung stem cells and the development of lung mimicking devices
... AT-II cells already demonstrated that AT-II cells can differentiate into AT-I cells ...AT-I cells after pneumonectomy has been ...AT-I cells proliferate and differentiate ...
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The cellular kinetics of lung alveolar epithelial cells and its relationship with lung tissue repair after acute lung injury
... for alveolar epithelial cells. T1α-pos cells (AEC1s) (Purity 90 ± 4%) were firstly separated from rat lung single cell suspension, then EpCAM-pos cells (AEC2s) were isolated (Purity 86 ...
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Alert cell strategy in SIRS-induced vasculitis: sepsis and endothelial cells
... various epithelial cells and vascular endothelial ...dendritic cells, and the overproduction of inflammatory ...some epithelial cells in major organs express inflammatory receptors on ...
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Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation
... ATII cells from free cholesterol-induced cyto- toxicity by exporting free ...cholesterol. Cells transfected with a non-functional mutant of ABCA3, ABCA3- Q215K, displayed excessive accumulation of ...
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