aminopeptidase A
Hypertension and Angiotensin II Hypersensitivity in Aminopeptidase A—deficient Mice
... Local concentrations of the vasopressor peptide, angiotensin II (AngII), depend upon the balance between synthesis and degradation. Previous studies of blood pressure (BP) regulation have focused primarily on the ...
6
Phosphonic analogues of phenylglycine as inhibitors of aminopeptidases: Comparison of porcine aminopeptidase N, bovine leucine aminopeptidase and aminopeptidase from barley seeds
... Abstract: Inhibitory activity of 14 phosphonic analogues of phenylglycine, substituted in aromatic ring by fluorine and chlorine, was determined towards porcine aminopeptidase N. The obtained data served as a ...
11
Use of arginine aminopeptidase activity in characterization of arginine utilizing mycoplasmas
... The The aminopeptidase activity of washed con- use of larger dilutions for the broth samples of centrated cell extracts, detected by hydrolysis of group B strains and strains not utilizi[r] ...
8
Pyruvate kinase is a dosage-dependent regulator of cellular amino acid homeostasis
... and SRM transitions suitable for robust relative quantification of the aminopeptidase AAP-S and serine hydroxymethyltransferase SHMT1 (Fig 4). Specific SRM signals corresponding to the other three proteins were of ...
14
Journal of Applied Pharmaceutical Science
... alanine aminopeptidase activity assay reaction mixture contained in ...alanine aminopeptidase activity is the amount of enzyme which catalyzes the liberation of 1 nmol of β- naphthylamine per hour at 37 ˚C ...
6
Enzymatic monitoring and control of a two-phase batch digester leaching system with integrated anaerobic filter
... The activity of free enzymes was measured for a range of hydrolytic enzymes. Since hydrolysis of substrates containing a high proportion of herbal material is the rate-limiting step in the biogas process [7], the ...
11
Krendl, Christian (2018): A GATA/TFAP2 transcription regulatory network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. Dissertation, LMU München: Medizinische Fakultät
... maintenance of pluripotency in mouse epiblast and ES cells. Cell 113, 631-642. Mitsui, T., Nomura, S., Okada, M., Ohno, Y., Kobayashi, H., Nakashima, Y., Murata, Y., Takeuchi, M., Kuno, N., Nagasaka, T., et al. (2003b). ...
124
Diagnostic value of interactions between members of the family Neisseriaceae and lectins
... The lectin agglutination test, coupled with the gamma-glutamyl aminopeptidase assay, is proposed as a rapid and accurate means of identifying clinical isolates of gonococci.... DOYLE ET [r] ...
5
Research of inhibition mechanism of morin on tumor cells aminopeptidase N
... that aminopeptidase N have played a very important role in all aspects of malignant tumor metastasis , including the degradation of thymosin and interleukin, resulting in immune system function decreased, which ...
7
Interspecies differences in membrane-associated protease activities of thyrocytes and their relevance for thyroid cancer studies
... In our study, lysosomal protease activity of DPP II was strongly expressed in thyrocytes of all species. This lack of interspecies differences was also reported in another study on the expression pattern of the lysosomal ...
7
Pseudomonas aeruginosa Leucine Aminopeptidase Influences Early Biofilm Composition and Structure via Vesicle Associated Antibiofilm Activity
... leucine aminopeptidase in biofilm development, as PaAP is one of the most abundant proteins in the ...soluble aminopeptidase alone or in combination with ΔPaAP OMVs possessed detachment ...
17
Placental Leucine Aminopeptidase/Oxytocinase Expression in Miscarriage
... leucine aminopeptidase, and increases in pregnant serum ...leucine aminopeptidase (P-LAP) as a promising agent to treat preeclampsia and preterm delivery (miscarriage) which are important complications in ...
10
Type II Secretion Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas
... It is intriguing to contemplate why LapA and PlaC, two very different exoenzymes, should overlap in terms of function. In one scenario, L. pneumophila utilizes both amino acids (generated by LapA) and lipids (generated ...
21
Binding of Transmissible Gastroenteritis Coronavirus to Cell Surface Sialoglycoproteins
... immobilized proteins were used for a virus overlay binding assay to compare TGEV and the mutants HAD3 and m10 (Fig. 2A). All three viruses bound to a protein (pAPN) migrating in a position where aminopeptidase N, ...
7
The puromycin sensitive aminopeptidase PAM 1 is required for meiotic exit and anteroposterior polarity in the one cell Caenorhabditis elegans embryo
... puromycin-sensitive aminopeptidase PAM-1 in both cell cycle progression and AP axis formation, further implicating proteolytic regulation in these ...sensitive aminopeptidase is also required for ...
12
The role of HLA B27 in inflammatory arthritis
... TAP is a heterodimeric transporter, consisting of TAP1 and TAP2, which is part of the ATP-binding cassette (ABC) transporter family. ABC transporters have a four-domain structure consisting of two hydrophobic ...
311
LOCALIZATION OF LEUCINE AMINOPEPTIDASE IN SERUM AND BODY FLUIDS BY STARCH GEL ELECTROPHORESIS
... Infiltrative diseases of the liver, i.e., sarcoidosis, lymphosarcoma, and Hodgkin's disease, carcinoma of the pancreas with obstruction of the common bile duct or metastatic to the liver[r] ...
6
Intestinal Assimilation of a Tetrapeptide in the Rat: OBLIGATE FUNCTION OF BRUSH BORDER AMINOPEPTIDASE
... Intestinal transport of glucose, amino acids, and peptides 16 occurs uphill against a concentration gradient by energy-dependent processes but hydrolytic activity of brush border amino-o[r] ...
11
Porcine aminopeptidase N binds to F4+ enterotoxigenic Escherichia coli fimbriae
... The addition of both APN polyclonal anti- serum and an anti-F4 fimbriae monoclonal antibody to IPEC-J2 cells also reduced ETEC adhesion (Figure 3 B).. Discussion.[r] ...
7
Feline aminopeptidase N is not a functional receptor for avian infectious bronchitis virus
... Receptor interaction between the virus and its host is the first step leading to a successful entry and productive rep- lication. Viruses increase fitness by adapting to environ- mental pressure through mutation and ...
10