AMP-activated protein kinase
AMP-Activated Protein Kinase and Glycogen Synthase Kinase 3β Modulate the Severity of Sepsis-induced Lung injury
... how AMP-activated protein kinase (AMPK), a major sensor and regulator of energy expenditure and production, affects development of organ injury and loss of innate capacity during polymicrobial ...
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AMP activated protein kinase: a potential therapeutic target for triple negative breast cancer
... action. AMP-activated protein kinase (AMPK), an energy sensor, can regulate protein and lipid metabolism responding to alterations in energy ...
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Role of AMP activated protein kinase in mechanism of metformin action
... liver. AMP-activated protein kinase (AMPK) is a major cellular regulator of lipid and glucose ...and protein is reduced; activity of the AMPK target, ACC, is also ...
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Mesoglycan attenuates VSMC proliferation through activation of AMP-activated protein kinase and mTOR
... AMP-activated protein kinase (AMPK) is a serine/ threonine protein kinase, which serves as an energy sensor in all eukaryotic cell ...
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Stimulation of Brain AMP-Activated Protein Kinase Attenuates Inflammation and Acute Lung Injury in Sepsis
... scure. AMP-activated protein kinase (AMPK) is a ubiquitous energy sensor enzyme and plays a key role in regulation of energy ho- meostasis and cell ...inflammatory protein-2 as well as ...
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AMP-activated protein kinase-α1 as an activating kinase of TGF-β-activated kinase 1 has a key role in inflammatory signals
... factor-b-activated kinase 1 (TAK1) in inflammatory signals, including Toll-like receptors (TLRs), its activating kinase still remains to be ...that AMP-activated protein ...
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Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK), RSVA314 and RSVA405, Inhibit Adipogenesis
... AMP-activated protein kinase (AMPK) is a sensor and regulator of cellular energy metabolism potentially implicated in a broad range of conditions, including obesity and Alzheimer’s ...this ...
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Augmenting energy expenditure by mitochondrial uncoupling: a role of AMP-activated protein kinase
... (2) AMP-activated protein kinase (AMPK), the master regulator of cellular energy ...uncoupling protein 1 (UCP1) elicited major metabolic effects both at the cellular/tissue level and at ...
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AMP-Activated Protein Kinase Is Required for the Macropinocytic Internalization of Ebolavirus
... Identification of host factors that are needed for Zaire Ebolavirus (EBOV) entry provides insights into the mechanism(s) of filovirus uptake, and these factors may serve as potential antiviral targets. In order to ...
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Identification of a nuclear export signal in the catalytic subunit of AMP-activated protein kinase
... the AMP-activated protein kinase, by virtue of its activation by the end product of ATP hydrolysis (Winder and Thomson, ...by AMP leads to the phosphorylation of Acetyl CoA carboxylase ...
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AMP activated protein kinase controls metabolism and heat production during embryonic development in birds
... that AMP-activated protein kinase (AMPK) is involved in the regulation of energy metabolism and heat production during development in the chicken ( Gallus gallus ...total protein, and ...
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AMP-activated protein kinase is required for the anti-adipogenic effects of alpha-linolenic acid
... [14,15]. In addition, n-3 PUFA also has many effects in- cluding stimulation of 5′AMP-activated protein kinase (AMPK) in adipose tissue [16]. AMPK is a heterotri- meric enzyme that plays key ...
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AMP activated protein kinase signaling in metabolic regulation
... AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular ...When activated by a deficit in nutrient status, AMPK stimulates glucose uptake and lipid oxidation to ...
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Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487
... AMP-activated protein kinase (AMPK) is a heterotrimeric Ser/Thr kinase consisting of catalytic (α) and regulatory (β and γ) subunits that acts as a key sensor of cellular and whole-body ...
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AMP-activated protein kinase regulates L-arginine mediated cellular responses
... The AMP-activated protein kinase (AMPK) [22], a protein consisting of three subunits α, β, and γ, is an important energy-sensing/signaling system by which cells sense and decode changes ...
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The regulation of heart AMP-activated protein kinase by long-chain fatty acids and hormones
... phosphorylase kinase by PKA and Ca^^. Levels of intracellular glucose and AMP also increased after adrenergic ...by AMP rather than stimulation of phosphorylase kinase is the important ...
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Suppression of Kaposi's Sarcoma-Associated Herpesvirus Infection and Replication by 5′-AMP-Activated Protein Kinase
... result, activated AMPK restricts infection by several RNA viruses by decreasing levels of fatty acid synthesis ...of activated AMPK (16, ...endogenous activated AMPK can dramat- ically enhance KSHV ...
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A possible role for AMP-activated protein kinase activated by metformin and AICAR in human granulosa cells
... Figure 1 Dose-dependent productions of IL-8 and GRO α stimulated with TNF- α . Dose-dependent productions of IL-8 (A) and GRO α (B) in KGN cells stimulated with TNF- α . Cultured cells were incubated with the indicated ...
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Baicalin ameliorates polycystic ovary syndrome through AMP-activated protein kinase
... by protein expression of total and phosphorylation of AMPK ...5α-R1 protein expression was increased in ovarian tissues of PCOS rats, and decreased by BAL treatment ...
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AMP activated protein kinase: the guardian of cardiac energy status
... creatine kinase promoter is also active in cardiac muscle, Young and coworkers were able to use Birnbaum’s mouse model to study the role of AMPK in the heart ...
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