Ampicillin/sulbactam
Optimal dilution susceptibility testing conditions, recommendations for MIC interpretation, and quality control guidelines for the ampicillin sulbactam combination
... This has been achieved for the ampicillin-sulbactam combination and at the clinically recommended dosage 2 g of ampicillin and 1 g of sulbactam every 6 to 8 h, favors a dilution testing [r] ...
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Original Article In vitro efficacy of meropenem in combination with colistin, ampicillin-sulbactam against multidrug-resistant blaNDM-1-positive acinetobacter baumannii strains
... Abstract: Multidrug-resistant Acinetobacter baumannii strains increase the mortality rate of patient after surgery. Evidences have showed that combined antibiotic treatments have presented more efficient than single ...
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T.E.A. Study: three-day ertapenem versus three-day Ampicillin-Sulbactam
... and Ampicillin-Sulbactam are both recommended as single agent treatments to address localized peritonitis by the SIS (Surgical Infections Society) and the IDSA (Infection Diseases Society of ...
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Ampicillin/Sulbactam versus Cefuroxime as antimicrobial prophylaxis for cesarean delivery: a randomized study
... data and chi-square Fisher exact tests for categorical data. The drug efficacy was accessed by development of an infection either at the surgical site or elsewhere e.g. urin- ary tract infection. The association between ...
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Sensitivity of levofloxacin in combination with ampicillin-sulbactam and tigecycline against multidrug-resistant Acinetobacter baumannii
... In the present study, all of the isolated MDR A. bau- mannii were resistant to all tested antibiotics except to colistin and polymixin B. It is an important alarming sign that represents a major epidemiological health ...
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<p>Comparison of Ceftizoxime Plus Ampicillin-Sulbactam versus Gentamicin Plus Ampicillin-Sulbactam in the Prevention of Post-Transplant Early Bacterial Infections in Liver Transplant Recipients: A Randomized Controlled Trial</p>
... A concern regarding the use of aminoglycosides is renal toxicity. It was estimated that renal toxicity was developed in 10 – 20% of patients who received aminoglycosides. 29 Based on the mentioned criteria for diagnosis ...
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Proposed changes in interpretive criteria and potency of ampicillin and ampicillin sulbactam disks for susceptibility tests
... Use of different breakpoints for the two types of disks is likely to produce artificial discrepancies between ampicillin and ampicillin-sulbactam disk test results similar to those noted[r] ...
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A randomized trial of tigecycline versus ampicillin sulbactam or amoxicillin clavulanate for the treatment of complicated skin and skin structure infections
... A phase 3b/4, randomized, open-label, comparative study was conducted in subjects with cSSSI between September 2006 and September 2008 at 77 centers worldwide. The protocol (Pfizer Inc, data on file) was approved by the ...
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A prospective, multi centre, randomized clinical study to compare the efficacy and safety of Ertapenem 3 days versus Ampicillin - Sulbactam 3 days in the treatment of localized community acquired intra-abdominal infection. (T.E.A. Study: Three days Ertapenem vs three days Ampicillin-sulbactam)
... pathogens. Ampicillin-Sulbactam is a commonly used “ first line ” antibiotic for intra-abdominal ...and Ampicillin-sulbactam are recommended as primary treatment agents for localized ...
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Interpretive standards and quality control limits for susceptibility tests with ampicillin sulbactam combination disks
... When sulbactam was added to the 10-,ug ampicillin disk, there was a significant increase in zone diameters with ampicillinresistant gram-negative bacilli, but the very susceptible strain[r] ...
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In vitro activity of colistin in combination with various antimicrobials against <em>Acinetobacter baumannii</em> species, a report from South Iran
... Introduction: Acinetobacter baumannii is a gram-negative,opportunistic pathogen responsible for resistant nosocomial infections especially in the intensive care units (ICUS).One reason for the failure in the treatment of ...
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<p>Clinical Outcomes Of Colistin In Combination With Either 6-G Sulbactam Or Carbapenems For The Treatment Of Extensively Drug-Resistant <em>Acinetobacter Baumannii</em> Pneumonia With High MIC To Sulbactam, A Prospective Cohort Study</p>
... with sulbactam (CL +SB) and those who received colistin with carbapenems ...of sulbactam was derived from ampicillin/sulbactam and cefoperazone/ ...
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Evaluation of regional antibiograms to monitor antimicrobial resistance in hampton roads, Virginia
... With E. coli, there is evidence of extended-spectrum β-lactamase (ESBL) production as seen with reduced susceptibility to third- and fourth-generation cephalospo- rins, ceftriaxone and cefepime, respectively. ESBLs are ...
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<p>Synergistic and Antagonistic Effects of Metal Nanoparticles in Combination with Antibiotics Against Some Reference Strains of Pathogenic Microorganisms</p>
... aureus , the antibacterial action of AgNPs with antibiotics (azithromycin, cefotaxime, ampicillin/ sulbactam, cefuroxime, fosfomycin, chloramphenicol, and oxytetracycline) were having a [r] ...
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CHEMISTRY OF β-LACTAM SULTAMICILLIN AS A MUTUAL PRODRUG OF AMPICILLIN AND SULBACTAM WORKS AS AN AZABICYCLO [3.2.0] HEPTANE CARBOPENAM BIOPRECURSOR
... known. Ampicillin/sulbactam is a combination of a β- lactam antibiotic and a β-lactamase ...inhibitor. Ampicillin works by binding to penicillin-binding proteins (PBPs) to inhibit bacterial cell wall ...
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Treatment of ventriculoperitoneal shunt infection and ventriculitis caused by Acinetobacter baumannii: a case report
... -lactam ampicillin with the β -lactamase inhibitor sulbac- tam, (ampicillin-sulbactam) ...inhibitors, sulbactam possesses the greatest intrinsic bac- tericidal activity against ...
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The susceptibility to fosfomycin of Gram-negative bacteria isolates from urinary tract infection in the Czech Republic: data from a unicentric study
... only), ampicillin, ampicillin/sulbactam (as a representative of amino- penicillins with β-lactamase inhibitors), trimethoprim- sulfamethoxazole (co-trimoxazole), ciprofloxacin and cefuroxime was ...
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Sulbactam-enhanced cytotoxicity of doxorubicin in breast cancer cells
... Although sulbactam has relatively low intrinsic biologi- cal activity, it has inherent activity against some bacterial species, including Neisseria gonorrhoeae, Bacteroides fra- gilis, and Acinetobacter ...that ...
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Optimizing Pharmacokinetic/Pharmacodynamics Principles & Role of Cefoperazone Sulbactam
... Based on the dose recommended, it may be important to increase the dose of Cefoperazone to optimize t>MIC in severe infections which may result in greater microbial clearance based on the principles mentioned above. ...
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CALORIMETRIC DETERMINATION OF CEFTRIAXONE AND SULBACTAM IN INJECTION DOSAGE FORM
... chromatography [14-22] and High performance thin layer chromatography [23] methods are reported for determination of ceftriaxone and sulbactum alone and in combination. Sridharan et al proposed a UV spectrophotometric ...
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