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An improved rat model for chronic inflammatory

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain

Chronic morphine use does not induce peripheral tolerance in a rat model of inflammatory pain

... from inflammatory cells can facilitate the ability of exogenous opioids to stimulate μ-receptor endocytosis in sensory neurons and thereby reduce the development of morphine ...with chronic arthritis, ...

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Action of AferBio (fermented food) in a rat inflammatory model

Action of AferBio (fermented food) in a rat inflammatory model

... treated with indomethacin showed more resistance. Based on these observations, we suggest that AferBio regulates the mechanisms triggered by the injection of Freund’s adjuvant. Cotton pellet-induced granuloma is a ...

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Chronic prehepatic portal hypertension in the rat: is it a type of Metabolic Inflammatory Syndrome?

Chronic prehepatic portal hypertension in the rat: is it a type of Metabolic Inflammatory Syndrome?

... systemic chronic inflammation would be another link between disordered lipid metabolism, inflammation and IR in the evolution of this experimental ...subclinical chronic low-grade inflam- mation, ...

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Improved rat model for studying Pneumocystis carinii pneumonia

Improved rat model for studying Pneumocystis carinii pneumonia

... The results of these studies therefore suggest that those rats that lost more than 15 g during cortisone acetate administration were markedly more immunosuppressed than the animals that [r] ...

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Improved Survival in the Suckling Rat Model of Group B Streptococcal Sepsis After Treatment with Nonsteroidal Anti-inflammatory Drugs

Improved Survival in the Suckling Rat Model of Group B Streptococcal Sepsis After Treatment with Nonsteroidal Anti-inflammatory Drugs

... The nonsteroidal anti-inflammatory drugs, indomethacin and ibuprofen, have been shown to increase survival in various animal models of Gram-negative or endotoxin shock.. To evaluate the [r] ...

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Depression and anxiety behaviour in a rat model of chronic migraine

Depression and anxiety behaviour in a rat model of chronic migraine

... The scales developed for rats in the present study showed that depression and anxiety were positively cor- related. Depression and anxiety are two classes of psy- chiatric disease. Major depressive disorder is a mood ...

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The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes

The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes

... Diabetes in humans is characterised by a progressive accumulation of complications which markedly increase morbidity and mortality. In both type 1 and type 2 diabetics, cardiovascular disease, especially coronary artery ...

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Middle cerebral artery alterations in a rat chronic hypoperfusion model

Middle cerebral artery alterations in a rat chronic hypoperfusion model

... cognitive deficits (19, 47). It is feasible that alterations in MCA properties may be involved in the cognitive decline described in the BCCAO-model (48). Our study shows a reduction in CSA and WT of the MCA after ...

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Acute versus chronic phase mechanisms in a rat model of CRPS

Acute versus chronic phase mechanisms in a rat model of CRPS

... These experiments tested the hypothesis that tibia fracture with cast immobilization can induce chronic increases in the NK1-receptor protein in the hindpaw skin and spinal cord of lumbar enlargement. At 4 or 16 ...

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CHRONIC KIDNEY DISEASE MIGHT LEAD TO HEPATIC DYSFUNCTION ON A CHRONIC HYPERTENSIVE RAT MODEL STUDY

CHRONIC KIDNEY DISEASE MIGHT LEAD TO HEPATIC DYSFUNCTION ON A CHRONIC HYPERTENSIVE RAT MODEL STUDY

... hypertensive rat model to evaluate the possible cardiovascular and hepatic dysfunctions on a chronic ...found inflammatory cell infiltration around heart, kidney and hepatic portal vein, we ...

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Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis

Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis

... the rat liver showed typical damage of neutrophilic infiltration, necrosis of hepatocytes, proliferation of in- flammatory cells and epithelial cells of bile duct and for- mation of bile ...

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Anti-inflammatory effect of AMPK signaling pathway in rat

model of diabetic neuropathy

Anti-inflammatory effect of AMPK signaling pathway in rat model of diabetic neuropathy

... Statistical analysis All data presented as Mean ± SEM. One-way ANOVA analysis followed by Tukey’s post hoc test was used for evaluation of blood glucose levels, inflammatory markers, MNCV and Western blotting ...

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Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model

Flurbiprofen loaded ethosomes - transdermal delivery of anti-inflammatory effect in rat model

... results in softening of ethosomal lipid bilayer. Therefore, the presence of ethanol in ethosomes formulation offers rapid permeation of entrapped drug molecules through skin. Additionally, it results in steady state flux ...

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The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis

<p>The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis</p>

... The current study demonstrated that the mastic signi fi - cantly reduced the total colitis index of the colon com- pared to the colitis group in the acetic acid – induced model of ulcerative colitis in rats. In the ...

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The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis

<p>The Anti-Inflammatory Effect of Pistacia Lentiscus in a Rat Model of Colitis</p>

... The current study demonstrated that the mastic signi fi - cantly reduced the total colitis index of the colon com- pared to the colitis group in the acetic acid – induced model of ulcerative colitis in rats. In the ...

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Rock1 Inhibitor Abrogates Chronic Rejection in Rat Cardiac Model System

Rock1 Inhibitor Abrogates Chronic Rejection in Rat Cardiac Model System

... clinically applicable, it may be faced with the complexity of the MHC in humans, definition of appropriate se- quences and the requirements of rapid synthesis at the time of transplantation. We have therefore focused on ...

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Anti-Inflammatory Effect of Nano-Silver in Chronic
Rhinosinusitis Mouse Model

Anti-Inflammatory Effect of Nano-Silver in Chronic Rhinosinusitis Mouse Model

... in inflammatory cell infiltration and interferon-gamma levels in nasal lavage ...decreased inflammatory cell infiltration and PAS-positive cells in nasal ...Th1 inflammatory response in the ...

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&alpha;7 Nicotinic acetylcholine receptor-mediated anti-inflammatory effect in a chronic migraine rat model via the attenuation of glial cell activation

&alpha;7 Nicotinic acetylcholine receptor-mediated anti-inflammatory effect in a chronic migraine rat model via the attenuation of glial cell activation

... Objective: To investigate the role of α7nAChR in CM and provide a new therapeutic target for CM. Materials and methods: Thirty-six male Sprague–Dawley rats were distributed randomly into control, CM, PNU-282987, and ...

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Anti-inflammatory and ultrastructural effects of Turkish propolis in a rat model of endotoxin-induced uveitis

Anti-inflammatory and ultrastructural effects of Turkish propolis in a rat model of endotoxin-induced uveitis

... repair of the outer nuclear layer of the neural retina; this hypothesis will be tested in a future study of propolis in chronic uveitis [29]. In conclusion, the therapeutic effects of propolis observed in this ...

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ANTI INFLAMMATORY ACTIVITY OF TRICHOLEPIS GLABERRIMA ON CARRAGEENAN INDUCED RAT PAW OEDEMA MODEL

ANTI INFLAMMATORY ACTIVITY OF TRICHOLEPIS GLABERRIMA ON CARRAGEENAN INDUCED RAT PAW OEDEMA MODEL

... hind rat paw odema method in albino rats at the dose of 100mg/kg, 200mg/kg and 400mg/kg, ...anti- inflammatory activity by carrageenan-induced rat paw oedema model was selected to induce the ...

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