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Ancient DNA (aDNA)

Ancient DNA from Human and Animal

Ancient DNA from Human and Animal

... on ancient DNA (aDNA) has the potential to enable molecular biologists and archeologists to decipher certain aspects of history by direct looking into the ...modern DNA and postmortem DNA ...

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Ancient DNA and the rewriting of human history: be sparing with Occam’s razor

Ancient DNA and the rewriting of human history: be sparing with Occam’s razor

... in ancient DNA (aDNA) technology are now beginning to make this more direct approach possible, facilitated by new sequencing technologies that are now capable of gen- erating gigabases of data at moderate ...

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Unravelling the complexity of domestication: a case study using morphometrics and ancient DNA analyses of archaeological pigs from Romania

Unravelling the complexity of domestication: a case study using morphometrics and ancient DNA analyses of archaeological pigs from Romania

... Recent ancient DNA (aDNA) research also indicates the incorporation of Euro- pean wild boar into domestic stock during the Neolithization ...Romanian ancient teeth with aDNA ...

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Paging through history: Parchment as a reservoir of ancient DNA for next generation sequencing

Paging through history: Parchment as a reservoir of ancient DNA for next generation sequencing

... Parchment represents an invaluable cultural reservoir. Retrieving an additional layer of information from these abundant, dated livestock-skins via the use of ancient DNA (aDNA) sequencing has been mooted ...

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Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics

Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics

... genetics, ancient DNA (aDNA), population genomics and, more recently, paleogenomics, have pro- vided strong support for Darwin’s contention that do- mestic animal populations and domestication from wild ...

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Ancient DNA in Archaeologically Charred Zea Mays L: Prospects and Limitations

Ancient DNA in Archaeologically Charred Zea Mays L: Prospects and Limitations

... of ancient DNA analyses owing to the exponential copying of small or highly deteriorated fragments of DNA, which then allowed for the preservation, sequencing and analysis of that remnant ...quaagga ...

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Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA

Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA

... of ancient DNA (aDNA) have enabled the study of ancient ...endogenous DNA begins to degrade and accumulates chemical ...of ancient molecules [2]. Further, when extracting DNA ...

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Paleogenomics: reconstruction of plant evolutionary trajectories from modern and ancient DNA

Paleogenomics: reconstruction of plant evolutionary trajectories from modern and ancient DNA

... the DNA (and/or RNA) fragments present in plant subfossils are still scarce (for review, see Gutaker and Burbano ...for DNA extraction includes a whole variety of tissues, such as fruits, seeds, leaves, and ...

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Crosslinks Rather Than Strand Breaks Determine Access to Ancient DNA Sequences From Frozen Sediments

Crosslinks Rather Than Strand Breaks Determine Access to Ancient DNA Sequences From Frozen Sediments

... T4 DNA ligase should greatly increase the yield of amplifiable aDNA ...to ancient DNA is very ...Contaminating DNA molecules can enter the procedure at different levels, so appropriate ...

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Assessing the Fidelity of Ancient DNA Sequences Amplified From Nuclear Genes

Assessing the Fidelity of Ancient DNA Sequences Amplified From Nuclear Genes

... of ancient DNA has relied almost exclusively on mitochondrial DNA (mtDNA) se- ...of ancient nuclear DNA (nuDNA) sequences, thereby allowing the characterization of genetic loci directly ...

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Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences

... human DNA that was sheared to short frag- ments of similar size to those in ancient ...details, DNA was extracted from the blood of a healthy human donor using the Gentra Puregene Blood Kit ...of ...

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Sometimes Hidden but Always There: Assumptions Behind Demographic Inference from Ancient DNA Data

Sometimes Hidden but Always There: Assumptions Behind Demographic Inference from Ancient DNA Data

... Similar criticism applies to tools commonly used in demographic inference using modern and ancient DNA such as STRUCTURE [24], ADMIXTURE [25], Finestructure, and Chromopainter [26]. These tools vary in ...

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A new model for ancient DNA decay based on paleogenomic meta analysis

A new model for ancient DNA decay based on paleogenomic meta analysis

... long-term DNA preservation, but we offer some caveats: fragmentation through depurination is a well-characterized process (63) and we do not propose that it is irrelevant for long-term DNA ...many ...

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Novel substrates as sources of ancient DNA: : prospects and hurdles

Novel substrates as sources of ancient DNA: : prospects and hurdles

... extract DNA from lithics as early as the ...satellite DNA from a 2200 year-old stone tool from British Columbia using nested PCR, while Hardy et ...and DNA within the microcracks of stone tools, and ...

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Ancient DNA elucidates the controversy about the flightless island hens (Gallinula sp.) of Tristan da Cunha

Ancient DNA elucidates the controversy about the flightless island hens (Gallinula sp.) of Tristan da Cunha

... DNA extractions on specimens from 1968 (Table 1) and older were carried out in a dedicated aDNA facility (LAF, Leiden, the Netherlands), which is physically isolated from the main laboratories. Before extractions ...

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Increased mitochondrial DNA diversity in ancient Columbia River basin Chinook salmon Oncorhynchus tshawytscha

Increased mitochondrial DNA diversity in ancient Columbia River basin Chinook salmon Oncorhynchus tshawytscha

... from ancient specimens, allowing for more direct characterizations of past dynamics ...from ancient samples has con- firmed large losses in diversity for many species including musk ox (Ovibos moschatus) ...

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Ancient DNA Resolves Identity and Phylogeny of New Zealand’s Extinct and Living Quail (Coturnix sp )

Ancient DNA Resolves Identity and Phylogeny of New Zealand’s Extinct and Living Quail (Coturnix sp )

... extract DNA from ancient tissue is now becoming routine, making it possible to assign species names to unknown museum specimens as well as constructing phylogenies for species ...

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Ancient and modern DNA reveal dynamics of domestication and cross continental dispersal of the dromedary

Ancient and modern DNA reveal dynamics of domestication and cross continental dispersal of the dromedary

... poor DNA preservation in arid regions poses significant technical challenges (33), there are only a few findings from hot areas, where ancient DNA (aDNA) contributed significantly to the ...

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Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains

Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains

... Previous ancient DNA studies have suggested that Neanderthals may have had light skin and reddish hair colour due to a particular non-synonymous variation in MC1R ...different DNA variants than found ...

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Paging through history : parchment as a reservoir of ancient DNA for next generation sequencing

Paging through history : parchment as a reservoir of ancient DNA for next generation sequencing

... Here we present a molecular archaeological analysis of parchment using two historical samples from the Borthwick Institute for Archives at The University of York dated palaeographically to the 17th (PA1) and 18th (PA2) ...

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