and Smooth Muscle Cell
Rapamycin inhibits vascular smooth muscle cell migration
... vascular smooth muscle cell (SMC) proliferation and migration contribute to the development of restenosis after percutaneous transluminal coronary angioplasty and accelerated arteriopathy after ...
8
Prevention of smooth muscle cell outgrowth from human atherosclerotic plaque by a recombinant cytotoxin specific for the epidermal growth factor receptor
... on smooth muscle cell outgrowth from human atherosclerotic ...human smooth muscle cells proliferating in culture and can prevent smooth muscle cell outgrowth from ...
7
Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation
... I. Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell ...Physiol Cell Physiol 316: C424 – ...
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Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... Mesangial cell proliferation is common in glomerulonephritis but it is unclear if proliferation is associated with any in vivo alteration in ...alpha-smooth muscle actin in a mesangial pattern, ...
13
Increased endothelial and vascular smooth muscle cell adhesion on nanostructured titanium and CoCrMo
... vascular cell function on polymers (Miller et al 2004, 2005; Dalby et al 2002; Iwanaga et al 2005) to ...vascular smooth muscle cell ...vascular cell responses when implementing ...
10
Specific receptors for leukotriene C4 on a smooth muscle cell line
... intact smooth muscle cell line, DDT1 MF-2 cells derived from the Syrian hamster vas ...constant cell number, specific [3H]LTC4 binding reached a plateau indicative of saturable binding ...DDT1 ...
5
Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage
... cardiac muscle (data not ...in-vitro smooth muscle cell differentiation in primary cultures of embryonic lung mesenchymal cells (Yang et ...the smooth muscle cells of the ...
10
PM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
... medium (SMGM). The following day, the cells were washed and transferred to 0.2% FBS-containing DMEM- F12 for 24 h, and subsequently treated with TAPM2.5 (15 μg/ml) or WSPM2.5 (3 μg/ml) for an additional 48 h. At the end ...
11
Effect of loading history on airway smooth muscle cell matrix adhesions
... Our results were obtained firstly in a stochastic-elastic computational model and then in a continuum model. We find that our discrete and continuum models produce similar qualitative behaviour, and in a future study we ...
26
The characterisation of human detrusor smooth muscle cell cultures
... functionally predominant (Harriss, Marsh, Birmingham & Hill 1995). Much of current conservative therapy relies on anticholinergic drugs (eg oxybutynin, tolterodine) or other drugs with anticholinergic effects (eg ...
241
Vascular Smooth Muscle Cell Stiffness and Adhesion to Collagen I Modified by Vasoactive Agonists
... vascular smooth muscle cells (VSMCs) integrin-mediated adhesion to extracellular matrix (ECM) proteins play important roles in sustaining vascular tone and ...skeletal muscle arterioles and ...
12
Regulation Of The Human Vascular Smooth Muscle Cell Transcriptome By Extracellular Matrix Stiffness
... sequencing of RNA from Ao and Co VSMCs grown on engineered polyacrylamide hydrogel surfaces tuned to physiologic and pathologic stiffness. Using several bioinformatic approaches, we compared the transcriptional ...
157
Distinct Effects of Ca2+ Sparks on Cerebral Artery and Airway Smooth Muscle Cell Tone in Mice and Humans
... ASM: airway smooth muscle; ASMCs: airway smooth muscle cells; CASMCs: cerebral artery smooth muscle cells; Ca 2+ sparks: spontaneous, transient local Ca 2+ elevations; RyRs: ry[r] ...
12
Protective Role for Properdin in Progression of Experimental Murine Atherosclerosis
... for smooth muscle cell actin (smooth muscle cells), high resolution imaging and subse- quent analysis showed that there were no significant differences in the % VSMC/plaque area between ...
9
Human airway smooth muscle maintain in situ cell orientation and phenotype when cultured on aligned electrospun scaffolds
... Human Airway Smooth Muscle Cell Orientation and Phenotype are altered when.. cultured on Aligned Electrospun Scaffolds.[r] ...
28
Protective Effect of Pyrogallol-phloroglucinol-6,6-bieckol from Ecklonia cava on Monocyte-Associated Vascular Dysfunction
... associated vascular smooth muscle cell proliferation and migration by decreasing the 25.. phosphorylations of ERK and AKT.[r] ...
11
The extracellular signal regulated kinase (ERK) pathway: a potential therapeutic target in hypertension
... vascular smooth muscle ...vascular smooth muscle cell growth and this, therefore, makes it an attractive target for the treatment of ...
7
Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity under high glucose conditions
... vascular smooth muscle cell (vSMC) prolifera- tion in vascular disease, particularly atherosclerosis, is controversial and unresolved ...vSMC cell proliferation is of potential therapeutic ...
9
Patent ductus arteriosus in mice with smooth muscle specific Jag1 deletion
... for smooth muscle cells (orange, anti-SM22a antibody) and endothelial cells (green, anti- PECAM1 antibody) revealed reduced vascular smooth muscle cell differentiation in the ductus ...
9
Heat shock protein 27 plays a protective role in thoracic aortic dissection by promoting cell proliferation and inhibiting apoptosis
... Antibodies against HSP27 have been detected in patients with cancer and coronary diseases, although the antibody levels in patients with coronary diseases were not asso- ciated with known coronary risk factors [19]. ...
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