ANG II
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
... the Ang II–mediated increase in blood ...the Ang II group was significantly increased com- pared with the saline control group (151 ± 7 mmHg versus 113 ± 4 mmHg; *P < ...
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Disruption of the Ang II type 1 receptor promotes longevity in mice
... to Ang II in the presence or absence of ...by Ang II ...to Ang II (Figure 8A). To further evaluate whether Ang II–induced downregulation of Nampt could impact Sirt3 ...
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Blood pressure regulation during hypotension in two teleost species: differential involvement of the renin angiotensin and adrenergic systems
... of Ang II on catecholamine release from the chromaffin ...system, Ang II does not elicit catecholamine release from the chromaffin tissue, and α-adrenoceptor-mediated catecholamine effects or ...
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NLRP3 inflammasome activation is involved in Ang II-induced kidney damage via mitochondrial dysfunction
... (Ang) II plays an important role in mitochondrial ...of Ang II in NLRP3 inflammasome activation and the involvement of mitochondrial dysfunction in this ...vitro, Ang II ...
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Ets 1 is a critical regulator of Ang II mediated vascular inflammation and remodeling
... of the complex formed at 4 hours was verified by the fact that 10 ng of an unlabeled (cold) oligo- nucleotide was able to potently compete with the labeled probe (lane 6). Furthermore, when a mutant oligonucleotide in ...
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A mouse model for Costello syndrome reveals an Ang II–mediated hypertensive condition
... renin–Ang II system. Treatment with captopril, an inhibitor of Ang II biosynthesis, prevented development of the hypertension condition, vascular remodeling, and heart and kidney ...
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The one two punch: knocking out angiotensin II in the heart
... Ang II plays an important role in the pathophysiology of cardiovascular ...lower Ang II lev- els by inhibiting conversion of Ang I to Ang II, but Ang II ...
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Angiotensin II depolarizes podocytes in the intact glomerulus of the Rat
... effects, Ang II is a growth hormone and contributes to the pathogenesis of glomerulosclerosis (4, ...of Ang II on proteinuria, it has been recently reported that it leads to an increase of ...
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Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis
... Angiotensin II (Ang II) stimulates the expression of NF- B, a transcription factor that regulates gene expression of inflammatory cytokines and surface adhesion molecules, leading to inflammation ...
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Effects of angiotensin II generated by an angiotensin converting enzyme independent pathway on left ventricular performance in the conscious baboon
... [Pro11DAla12] Ang I, a specific substrate for human chymase, was given in consecutive fashion as a ...an Ang II receptor antagonist. [Pro11DAla12]Ang I significantly increased LV systolic and ...
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Endothelin 1 is an autocrine/paracrine factor in the mechanism of angiotensin II induced hypertrophy in cultured rat cardiomyocytes
... in ANG II-induced hypertrophy of neonatal rat cardiomyocytes by use of synthetic ET-1 receptor antagonist and antisense oligonucleotides to preproET-1 (ppET-1) ...well. ANG II upregulated ...
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Induction of platelet derived growth factor A chain and c myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells
... cycloheximide abolished the elevation of the PDGF A-chain mRNA. Taken together, our data show that exposure of RASM cells to Ang II results in the sequential activation of c-myc and PDGF A-chain mRNA ...
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The cardioprotective and antiarrhythmic effects of Nardostachys chinensis in animal and cell experiments
... Angiotensin II (Ang II), as a vital mediator, could cause cardiac hypertrophy ...by Ang II and the mRNA ex- pressions of atrial natriuretic peptide (ANP), B-type natri- uretic peptide ...
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Regulation of angiotensin II receptor AT1 subtypes in renal afferent arterioles during chronic changes in sodium diet
... of ANG II. Each recording was started when ANG II was introduced into the renal artery infusion ...of ANG II into the infusion line and the onset of the renal vascular ...
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Role of AT1 receptors in the resetting of the baroreflex control of heart rate by angiotensin II in the rabbit
... Angiotensin II (Ang II) resets the baroreflex control of heart rate to a higher blood ...via Ang II receptors in the area postrema, but it is not known if these are of the AT1 or AT2 ...
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Ang II–stimulated migration of vascular smooth muscle cells is dependent on LR11 in mice
... and Ang II–stimulated migration and attachment of SMCs from these mice were largely ...by Ang II. Overproduction of sLR11 decreased the sensitivity of Ang II–induced activation ...
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Insulin attenuates agonist mediated calcium mobilization in cultured rat vascular smooth muscle cells
... angiotensin II (ANG II)-induced increments in cytosolic calcium in cultured rat vascular smooth muscle cells ...nM ANG II in a dose-dependent manner (ANG II alone, 721 +/- ...
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The absence of intrarenal ACE protects against hypertension
... to Ang II infu- sion (Supplemental Figure ...2-week Ang II infusion had no effect on FL-SPAK or SPAK2 but significantly decreased KS-SPAK and increased the FL-SPAK/ KS-SPAK ratio by more than ...
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Original Article miRNA-134 suppresses angiotensin II-induced vascular smooth muscle cell dysfunction by targeting angiotensin II type 1 receptor (AT1R)
... in Ang II-induced VSMC ...with Ang II induced cell proliferation in a time- VSMCs were transfected with miRNA-134 mimics or inhibitor for 12 hours, the mitochondrial membrane potential (D) and ...
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Role of endothelium on the abnormal Angiotensin mediated vascular functions in epileptic rats
... were stretched to a basal tension of 1.5 g before allowing them to equilibrate for 60 min in the bath fluid, which was changed every 15 min. Endothelial integrity was qualitatively assessed by the degree of relaxation ...
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