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Animal Studies

Methodological quality of systematic reviews of animal studies: a survey of reviews of basic research

Methodological quality of systematic reviews of animal studies: a survey of reviews of basic research

... in animal research can help rationalize human clinical ...human studies is well recognised, but lack of systematic review of this evidence can lead to a sort of research bias that has seldom been previously ...

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The british animal studies network

The british animal studies network

... nimal Studies, as the recent exchange of emails on the internet discussion site h- animal revealed, is not perceived to be a discipline by those involved in ...on. Animal Studies is a field ...

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SYRCLE’s risk of bias tool for animal studies

SYRCLE’s risk of bias tool for animal studies

... in animal intervention studies at present because protocols for animal studies are not yet registered in a central, publicly accessible ...all animal experiments at inception [19,20], ...

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The Potential of Adaptive Design in Animal Studies

The Potential of Adaptive Design in Animal Studies

... funded studies which lack the necessary resources and infrastructure ...complex studies, therefore, may be better suited to the industrial ...shorter studies with fewer subjects may be greater than ...

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RETROLENTAL FIBROPLASIA: ANIMAL STUDIES

RETROLENTAL FIBROPLASIA: ANIMAL STUDIES

... Engorgement and Hyperplasia of the Iris, Tunica Vasculosa Lentis and Retina in RETROLENTAL FIBROPLASIA: ANIMAL STUDIES: Induced Vascular. Services[r] ...

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Sample Size Calculation in Animal Studies
Using Resource Equation Approach

Sample Size Calculation in Animal Studies Using Resource Equation Approach

... pre-clinical studies in vitro (test tube or cell cultures) and in vivo (animal experiments) to examine preliminary efficacy, toxicity, and pharmacokinetics ...Pre-clinical animal studies ...

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Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

... same animal can be especially informative and add statistical ...the animal, which will allow acceptable signal-to-background ratio and dynamic range for experimental ...therapeutic studies. Because ...

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Animal geographies, anarchist praxis and critical animal studies

Animal geographies, anarchist praxis and critical animal studies

... non-human animal relations. At the very least if more animal geographers could commit themselves (and their work) through embracing a critical animal praxis that works within a total liberation ...

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Mechanisms of endothelial dysfunction in rheumatoid arthritis: lessons from animal studies

Mechanisms of endothelial dysfunction in rheumatoid arthritis: lessons from animal studies

... The studies were conducted mainly on the AIA model, and the assessment of ED was made at a time at which inflammatory symptoms are maximal (that is, be- tween day 24 and 35 after the injection of Mycobacterium ...

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Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies

Effect of coadministration of rifampicin on the pharmacokinetics of linezolid: clinical and animal studies

... spectrophotometer (NanoDrop Products, Wilmington, DE, USA). cDNA was synthesized with 2 μg of total RNA using a High Capacity cDNA Reverse Transcrip- tion Kit® (Applied Biosystems, Foster city, CA, USA), ac- cording to ...

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Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies

Regulation of reverse cholesterol transport - a comprehensive appraisal of available animal studies

... initial studies on this pathway bile acids have been shown to be essential as acceptors for intestinal cho- lesterol excretion, the nature of the cholesterol acceptors in the bile duct diversion experiments ...

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Clinical, microbiological, and experimental animal studies of Candida lipolytica

Clinical, microbiological, and experimental animal studies of Candida lipolytica

... The index isolate caused persistent fungemia with catheter-associated Candida thrombophlebitis, the second isolate was from a polymicrobial sinusitis, and the remaining four isolates wer[r] ...

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Education for ethics : investigating the contribution of animal studies to fostering ethical understanding in children

Education for ethics : investigating the contribution of animal studies to fostering ethical understanding in children

... early animal protection ...of animal-focused literature on humane attitudes and values development, which illustrates the role of animals in values ...possible. Animal advocacy groups such as the ...

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Gene Therapy for Lumbar Disc Disease; An Overview of Animal and Human Studies

Gene Therapy for Lumbar Disc Disease; An Overview of Animal and Human Studies

... Considering intervertebral disc degeneration as an imbalance between the synthesis and degrading of the components, discontinuing/halting the catabolic cascade can be a reasonable therapeutic goal. Although most ...

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Studies on DNA Replication in Animal Cells (Annual Report)  EUR 2959

Studies on DNA Replication in Animal Cells (Annual Report) EUR 2959

... 4 — DISCUSSION When DNA Avas extracted from cells AvithdraAvn after a short in vivo 31I thymidine pulse, most of the radioactive label Avas found in a deoxyribonucleic material which dif[r] ...

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The Hi NOON neural simulator and its applications to animal, animat and humanoid studies

The Hi NOON neural simulator and its applications to animal, animat and humanoid studies

... Hi- NOON is an object-oriented neuronal circuit simulator specifically developed for studying the neurophysiologi- cal basis of behaviour in real animals and in situated artificial systems. It simulates changes in ...

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Technology, welfare and intensive animal farming : case studies of the poultry and pig industries

Technology, welfare and intensive animal farming : case studies of the poultry and pig industries

... The chapter addresses two central questions. Firstly, how do organisations interact with each other and the farm and shape technology? Secondly, how does new technology affect animal welfare? The answers to these ...

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The development of response surface pathway design to reduce animal numbers in toxicity studies

The development of response surface pathway design to reduce animal numbers in toxicity studies

... The second in vivo study consisted of 24 female NMRI mice of SPF quality (15–21 g), randomly divided into 4 groups comprising 3, 5, 7 and 9 mice per cage, respect- ively. The mice were supplied 1 week before the experi- ...

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Plasmid profile analysis in epidemiological studies of animal Salmonella typhimurium infection in Japan

Plasmid profile analysis in epidemiological studies of animal Salmonella typhimurium infection in Japan

... typhimurium isolates from five rearing houses showed identical or very similar plasmid patterns in strains from each of those houses; a slight difference due to the presence or absence o[r] ...

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Pain assessment in animal models: do we need further studies?

Pain assessment in animal models: do we need further studies?

... suitable animal model for studying ...for studies where results can be reproduced in ...the animal facility, which optimizes the conditions for ...approve studies involving pigs as opposed to ...

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