Anion transporter
Association analysis of the SLC22A11 (organic anion transporter 4) and SLC22A12 (urate transporter 1) urate transporter locus with gout in New Zealand case control sample sets reveals multiple ancestral specific effects
... Association analysis of the SLC22A11 organic anion transporter 4 and SLC22A12 urate transporter 1 urate transporter locus with gout in New Zealand case-control sample sets reveals multip[r] ...
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Urolithiasis and hepatotoxicity are linked to the anion transporter Sat1 in mice
... playing important roles in many biochemical reactions. The regu- lation of oxalate and sulfate homeostasis is complex, with the kid- ney and liver playing critical roles. The sulfate anion transporter–1 ...
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Organic anion transporter 3- and organic anion transporting polypeptides 1B1- and 1B3-mediated transport of catalposide
... organic anion transporter 1 (OAT1), OAT3, organic anion transporting polypep- tide 1B1 (OATP1B1), OATP1B3, organic cation transporter 1 (OCT1), OCT2, P-glycoprotein (P-gp), and breast cancer ...
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Molecular and biological characterization of the Amblyomma americanum organic anion transporter polypeptide
... organic anion transporter polypeptide among genes that are induced or differentially upregulated in ticks that have attained appetence and/or been exposed to feeding stimuli (Mulenga et ...
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Genetic knockdown of a single organic anion transporter alters the expression of functionally related genes in Malpighian tubules of Drosophila melanogaster
... In the present study, we assessed the functional importance of each of the three transporters by RNAi knockdown or P-element insertion mutation of a single transporter gene. Had we simply correlated the mRNA ...
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Protective Effect of Aloe vera (Aloe barbadensis Miller) on Erythrocytes Anion Transporter and Oxidative Change
... The purpose of this study was to evaluate the ability of aqueous extract of Aloe barbadensis Miller (Aloe vera) on oxi- dative damage and Anion Exchanger 1 (AE1, also known as Band 3) expression in human ...
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Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis
... restore anion secretion in CF tis- ...bicarbonate transporter, may be able to compensate for the loss of CFTR function in individuals with CF (15, 85, ...
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Role of chloride and intracellular pH on the activity of the rat hepatocyte organic anion transporter
... cotransport. As the presence of Cl- is essential for but not directly coupled to BSP transport, binding of 35S-BSP to hepatocytes was determined at 4 degrees C. This revealed an approximately 10-fold higher affinity of ...
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Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA
... multidrug resistance- associated protein (MRP) MRP1, and cMOAT and MRP1 are members of the same sub-family of adenine nucleotide binding cassette transporters. In contrast to MRP1, cMOAT was predominantly found ...
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Polymorphic variants of SLCO1B1 in neonatal hyperbilirubinemia in China
... basolateral (sinusoidal) membrane of human hepato- cytes, encoded by the gene of the solute carrier organic anion transporter family member 1B1 (SLCO1B1) [4]. At this point, OATP1B1 is conjugated with ...
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Expression of the Genes OsNRT1 1, OsNRT2 1, OsNRT2 2, and Kinetics of Nitrate Uptake in Genetically Contrasting Rice Varieties
... OsNRT2.1 transporter is responsible for absorption of up to 75% of the available nitrate in Arabidopsis thaliana, while the huge differences regarding the induction response levels of the NRT2s, as observed for ...
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Genetic Processes of Iron and Zinc Accumulation in Edible Portion of Crops and Their Agro-Biofortification: A Review
... Grasses (Strategy II plants), such as corn, wheat and rice, use the chelation-based response to Fe-deficiency. Grasses release small molecular weight compounds known as the mugineic acid (MA) family of phytosiderophores ...
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cocaine piperidine based analogs sar 2 pdf
... The synthesis and monoamine transporter activity of additional members of a series of 3,4- disubstituted piperidines (truncated analogues of the WIN series) are described. All members of this series were prepared ...
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Interstellar dehydrogenated PAH anions: vibrational spectra
... Interstellar PAH anions are likely to exist in cold dense regions where a PAH molecule can easily attract an electron to form a PAH anion that shows important characteristic features in IR. This study reports the ...
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Schönberger, Stefanie (2013): Phosphorus, sulfur and pyridine: a unique combination to a great structural diversity. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Figure 8 shows the structure of the anion in 3 and selected atom distances and bond angles are listed.. Structure of the anion in 3.[r] ...
250
Sotagliflozin, the first dual SGLT inhibitor: current outlook and perspectives
... Sotagliflozin is a dual sodium–glucose co-transporter-2 and 1 (SGLT2/1) inhibitor for the treatment of both type 1 (T1D) and type 2 diabetes (T2D). Sotagliflozin inhibits renal sodium–glucose co-transporter ...
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Anion templated self assembly From anion complexes to the formation of supramolecular 2D networks
... chemically rationalised, was obtained using 1:1 and 1:3 model in most of the anion interactions. In most cases, the fitting of the three-species model (i.e. 1:1, 1:2 and 1:3) would not allow the convergence of the ...
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Expression and regulation of drug transporters in vertebrate neutrophils
... “False negatives” may occur due to the inherent biological variation of the experimental approach, solubility issues or the fact that the compound cannot reach its intracellular target. In the latter case, we suggest ...
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Oxy anion accelerated rearrangements
... Depending on the reactivity of the particular alkoxide, three parameters, counterion, solvent, and reaction temperature, were altered to increase or decrease the severity of the rearrang[r] ...
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Role of an Expanded Inositol Transporter Repertoire in Cryptococcus neoformans Sexual Reproduction and Virulence
... inositol transporter in ...glucose transporter gene family has been identified to differentially control glucose uptake, and two permease homologs, Snf3 and Rgt2, function as sensors rather than ...
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