Anti-nuclear antibody
An automatic segmentation and classification framework for anti-nuclear antibody images
... tissues. Anti-Nuclear Antibody (ANA) is an autoantibody produced by the immune system directed against the self body tissues or cells, which plays an important role in the diagnosis of autoimmune ...
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Pattern and Frequency of Anti-nuclear Antibody Positivity in Paediatric Rheumatic Diseases
... tissue disease—an apparently distinct rheumatic disease syndrome associated with a specific antibody to an extractable nuclear antigen (ENA). Am J Med.1972; 52(2):148-59. 23. Gonzalez EN, Rothfield NF. ...
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Efficacy of subcutaneous tocilizumab in patients with rheumatoid arthritis and systemic sclerosis overlap syndrome: a report of two cases and review of the literature
... Anti-nuclear antibody (ANA) was 1280× (centromere), anti-cyclic citrullinated peptide antibody (ACPA) was 150 U/ml (normal value ...and anti-centromere antibody was ...
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Automated tests of ANA immunofluorescence as throughput autoantibody detection technology: strengths and limitations
... Anti-nuclear antibody assay (ANA) is the screening test of choice for diagnosis of almost all systemic autoimmune rheumatic diseases (SARDs) because of its greater sensi- tivity compared with other ...
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Screening for IgG4 type anti nuclear antibodies in IgG4 related disease
... serum anti-nuclear antibody (ANA) in IgG4-RD patients and compared them with those in pa- tients with systemic autoimmune diseases such as sys- temic lupus erythematosus (SLE), Sjögren’s syndrome ...
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Successful use of eculizumab to treat atypical hemolytic uremic syndrome in patients with inflammatory bowel disease
... ANA: Anti Nuclear Antibody; anti APL Ab: Anti Phospholipid Antibody; anti CL: Anti Cardiolipin; aPTT: Activated Partial Thromboplastin Time; CAPS: Catastrophic ...
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AYURVEDIC MANAGEMENT OF SCLERODERMA (UTTANA VATARAKTA) – A CASE STUDY .......
... USG reveals that mild hepato- spleenomegaly, chest X-ray & ECG-WNL. Hematological reports reveals that Anti nuclear antibody test (ANA test) – positive, Hb% -9.3 gm%,ESR-28 mm/hr , TLC,DLC and ...
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Sustained benefit from combined plasmapheresis and allogeneic mesenchymal stem cells transplantation therapy in systemic sclerosis
... of anti-topoisomerase (anti- scl70) autoantibodies, suggesting systemic effect of MSCs ...decreased anti- nuclear antibody (ANA) titer, and improvement in the MRSS and Health Assessment ...
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Comorbid connective tissue diseases and autoantibodies in lymphangioleiomyomatosis: a retrospective cohort study
... ANA: Anti-nuclear antibody; ANCA: Anti- neutrophil cytoplasmic antibody; APS: Antiphospholipid antibody syndrome; ARS: Aminoacyl-tRNA synthetase; BAFF: B-cell activating factor; ...
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Serum BAFF and APRIL levels in patients with IgG4 related disease and their clinical significance
... ANA: anti-nuclear antibody; APRIL: a proliferation-inducing ligand; BAFF: B cell-activating factor of the tumor necrosis factor family; BCMA: B cell maturation antigen; BLys: B-lymphocyte stimulator; ...
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The inclusion of N terminal pro brain natriuretic peptide in a sensitive screening strategy for systemic sclerosis related pulmonary arterial hypertension: a cohort study
... Abbreviations 6MWD: Six-minute walk distance; ANA: Anti-nuclear antibody; anti-cent: Anti-centromere antibody; anti-Scl70: Anti- topoisomerase-1 antibody; ASCS: Australian Scleroderma Co[r] ...
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Nonspecific interstitial pneumonia: clinical associations and outcomes
... AKA: Anti-keratin antibody; ANA: Anti-nuclear antibody; APF: Anti-perinuclear factor; ATS: American Thoracic Society; BALF: Bronchoalveolar lavage Fluid; CCP: Anti-cyclic ...
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Expression of the RANK/RANKL/OPG system in the human intervertebral disc: implication for the pathogenesis of intervertebral disc degeneration
... To further identify the inhibitory effect of RANKL sig- naling on the expression of catabolic factors by human IVD cells, the activity of RANKL was next specifically neutralized by anti-human RANKL monoclonal ...
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The TICOPA protocol (TIght COntrol of Psoriatic Arthritis): a randomised controlled trial to compare intensive management versus standard care in early psoriatic arthritis.
... modifying anti-rheumatic drug; DMEC: Data monitoring and ethics committee; dsDNA Ab: Double stranded DNA antibodies; EUC: Electrolytes, urea & creatinine; FBC: Full blood examination; GCP: Good clinical ...
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Antibodies to carbamylated α enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti citrullinated protein antibodies
... For antibody purification, plasma samples from patients with RA with a strong anti-CEP-1 antibody response (n = 5) or a strong anti-CCP2 antibody response (n = 38) were collected at the ...
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Clinical Reasoning: A 35-year-old woman with acute seizures and behavior change
... example, anti-Hu antibody limbic encephalitis is more frequently seen in small-cell lung cancers, anti-Ma antibody with testis or lung cancers, and amphiphysin antibody with breast and ...
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In vitro Interaction and Colocalization of HSV-1 ORF P with a Cellular Splicing Factor (SC35) Using Pulldown Assay
... In vitro interaction of HSV-1 ORF P with a cellular splicing factor (SC35). GST pulldown is a method usually used to determine protein-protein interactions in vitro. This method was used in this work to determine the ...
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Localization of CD26/DPPIV in nucleus and its nuclear translocation enhanced by anti-CD26 monoclonal antibody with anti-tumor effect
... the nuclear fraction, biotin-labeled CD26 decreased in the membrane fraction within one hour following 1F7 treat- ment ...the nuclear fraction, before and after treatment with IgG 1 ...the nuclear ...
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Autoimmune hepatitis related autoantibodies in children with type 1 diabetes
... ANA and SMA are clues for the diagnosis of AIH type 1. They may be consequences of liver injury rather than the cause. They typically lack disease specificity, fluctuate in titer, and variably appear and disappear in ...
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Anti tumor activity and toxicokinetics analysis of MGAH22, an anti HER2 monoclonal antibody with enhanced Fcγ receptor binding properties
... monoclonal antibody (mAb) trastuzumab ...direct anti-proliferative activity, antibody-dependent cell-mediated cytotoxicity (ADCC), and presentation of antigenic determinants of opsonized cells to ...
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