anti-tumor activity
Evaluation of antimicrobial activity, Minimum Inhibitory Concentration (MIC) & Anti tumor activity of Elettariacardamomum and Ferula assa foetida leaves
... for anti-tumor activity was done using carrot disc overlaid with 100ul of Agrobacterium tumefaciens ...gall tumor disease in a extensive range of plants including most dicotyledons, some ...
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Synthesis of benzothiazole selenato complexes and determination of its anti-tumor activity
... complexes of heterocyclic compounds and their Ni (II), Pd (II), Pt (I), Cu (II) complexes have also been synthesized. Heterocyclic r ing system like benzothiazole and few metals like Zn (II,) Pt (II), Cu (II), Ni (II) ...
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Elacestrant (RAD1901) exhibits anti tumor activity in multiple ER+ breast cancer models resistant to CDK4/6 inhibitors
... 50]. Anti-tumor activity observed from the combination ...single-agent activity since the model has been shown to be insensitive to fulvestrant ...ER-dependent tumor growth and ...
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<p>Enhancing Anti-Tumor Activity of Sorafenib Mesoporous Silica Nanomatrix in Metastatic Breast Tumor and Hepatocellular Carcinoma via the Co-Administration with Flufenamic Acid</p>
... Sorafenib (SFN), an orally administered multi-kinase inhi- bitor, was approved by the FDA for the clinical treatment of metastatic renal cell carcinoma and advanced hepatocellular carcinoma. 17 The therapeutic effects of ...
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A novel immunomodulatory hemocyanin from the limpet Fissurella latimarginata exhibits outstanding anti tumor activity in melanoma
... proven anti-cancer ...new anti-cancer candidates with improved immunological ...potent anti-tumor activity, delaying tumor growth and increasing the survival of mice challenged ...
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ANTI TUMOR ACTIVITY OF FRUIT EXTRACTS OF MOMORDICA DIOICA ROXB
... In the present study we have undertaken the evaluation of MDR fruit extracts for its potential anti-tumor activity. A phytochemical is a natural bioactive compound found in plant which is known in ...
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Anti Tumor Activity of Phloretin in Treatment of Induced Hepatocellular Carcinoma in Rats
... This study aims to evaluate the anti-tumor activity of phloretin in treatment of induced HCC in rats. Fifty adult male albino rats were divided into five groups (n=10, each). Group I (control group), ...
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Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity
... 4b (propionyloxy) possessed good antiproliferative activi- ties against the Hep-G2, A549, BGC-823 and MCF-7 cell lines, they showed no inhibition against the PC-3 cell line. In the PC-3 assay, the butyryloxy compound 4c ...
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Expression of miR-17-92 enhances anti-tumor activity of T-cells transduced with the anti-EGFRvIII chimeric antigen receptor in mice bearing human GBM xenografts
... Therapy of mice bearing intracranial glioma xenografts 5- to 6-week-old NOD/Shi-scid,IL-2Rr KO Jic (NOG) fe- male mice (Jackson Laboratory, Bar Harbor, ME) were used in the experiments. Animals were handled in the Animal ...
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Anti-tumor activity of the beta-adrenergic receptor antagonist propranolol in neuroblastoma
... demonstrated anti-NB activity for the COX-2 inhibitor celecoxib via effects of p53/p73 and VEGF signaling [31,34,35] the effects of celecoxib in combination with propranolol were ...
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Artesunate shows potent anti-tumor activity in B-cell lymphoma
... aggressive tumor growth in a xenograft ...prominent anti-lymphoma activity in vivo, suggesting it to be a relevant drug for treatment of B-cell ...
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Synthesis and Anti-Tumor Activity of Oleanolic Acid Derivatives
... gp130.By combining the three-dimensional crystal structure (PDB: 3UIH) of Survivin protein in the PDB database, analyzing the interaction between known Survivin small molecule inhibitor and target enzyme using molecular ...
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Synthesis and Anti-Tumor Activity of Oleanolic Acid Derivatives
... Abstract: With the computer drug-aided design and the key amino acid residue fragment of the target protein analyzed on the basis of simulated docking of Survivin and known active small molecules, the active groups ...
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Interleukin-1 alpha increases anti-tumor efficacy of cetuximab in head and neck squamous cell carcinoma
... some anti-tumor activity in athymic nude mice where NK cells (and not T cells) are present ...cell activity, we initially proposed that NK cells may be involved in the anti-tumor ...
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Membrane Interactivity of Non-steroidal Anti-inflammatory Drugs: A Literature Review
... their anti-inflammatory and anti- tumor activity by inhibiting COX indirectly through an alteration of the lipid environments surrounding membrane-associated enzyme ...beneficial ...
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Synthesis of novel β-carboline derivatives with potential antimicrobial and anti helminthic activities
... possess anti-tumor activity through multiple mechanisms, such as targeting DNA [2], suppressing the activity of topoisomerase [3], CDK [4] and IjK ...potent anti cancer activities[6-8] ...
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IN-VIVO ANTI-TUMOR EFFECT OF 5-FLUOROURACIL LOADED CHITOSAN-SODIUM DEOXYCHOLATE NANOPARTICLES
... antitumor activity of the prepared chitosan- sodium deoxycholate nanoparticles loaded with ...In-vivo anti-tumor effect was studied on solid ehrlich carcinoma (SEC) tumor bearing Swiss albino ...
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Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells
... HuCC-T1 tumor-bearing ...the tumor volume increased ...of tumor volume, indicating that EGCG has anti-tumor activity against the in vivo tumor xenograft model of HuCC-T1 ...
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Inhibition of cyclin dependent kinase 9 by dinaciclib suppresses cyclin B1 expression and tumor growth in triple negative breast cancer
... the anti-tumor activity of dinaciclib in triple negative breast cancer (TNBC) patient derived xenograft (PDX) and cell lines in vitro and in ...
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Discovery of a small molecule targeting SET-PP2A interaction to overcome BCR-ABL T315I mutation of chronic myeloid leukemia
... the anti-tumor activity of TGI1002 with following evidence: (1) shRNA-mediated knock-down of SET expression significantly reduced the sensitivity of K562 cells to TGI1002; (2) TGI1002 could directly ...
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