Anti-tumour
Prostate transglutaminase (TGase 4) antagonizes the anti tumour action of MDA 7/IL 24 in prostate cancer
... MDA-7 has been tested for its clinical application as an anti-cancer treatment option. Using an adenoviral- based delivery method, MDA-7 has been shown to have an anti-tumour effect in ovarian, lung, ...
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Liposomal Nanoformulation of Piperlongumine for Improved Aqueous Solubility and Enhanced Anti-tumour Activity In-vitro
... US FDA because both products are able to enhance the apparent solubility and therapeutic efficacy of the drug in cancer. Therefore, the primary objective of this study was to develop a liposomal nanoformulation, in which ...
11
Demonstration of anti-tumour bystander killing with prodrug-preloaded suicide gene-engineered tumour cells: a potential improvement for cancer therapeutics
... TK+ve tumour cells would be exposed to GCV in vitro, in order to pre-load the tumour cells with GCV, wash the excess GCV away and then inject the cells for study of their in vivo bystander ...TK+ve ...
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Anti-Tumour Effect of two Persicaria Species Seeds on Colon and Prostate Cancers
... The results showed that there was a potential cytotoxicity of two Persicaria species seeds against two human cancer cell lines. Further investigations are recommended to identify the active principle responsible for ...
10
Anti tumour activity of bisphosphonates in preclinical models of breast cancer
... on tumour growth in bone, reducing progression of osteolytic lesions, inducing osteoclast apoptosis, inhibiting formation of new bone metastases, increasing cancer cell apoptosis and reducing tumour ...
13
Heat Shocking of Murine Malignant Mesothelioma Cells Enhances Their Effectiveness as an Autologous Anti Tumour Vaccine
... subsequent tumour rechal- lenge. However, as with many tumour immuno-therapies the ...local anti-tumor responses, at possibly the most relevant ...plus anti-CD40 combined adjuvant ...
10
Mesenchymal stromal cells (MSCs) and colorectal cancer: a troublesome twosome for the anti-tumour immune response?
... The tumour microenvironment (TME) is an important factor in determining the growth and metastasis of colorectal cancer, and can aid tumours by both establishing an immunosuppressive milieu, allowing the ...
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Anti tumour activity of longikaurin A (LK A), a novel natural diterpenoid, in nasopharyngeal carcinoma
... Many diterpenoids have been proven to have significant anti-tumour effects in vivo [8,37] (Fan QQ et al., 2010; Zhou GB et al., 2007). In vivo , LK-A administered every other day exhibited a similar or even ...
11
Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4
... to tumour growth, several groups have explored the roles of EphB4 in this process, many using over-expression strategies to reconstruct or block either forward or reverse signaling with signaling defective ...
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Anti tumour effects of resveratrol and pterostilbene on ovarian cancer
... Diet has long been associated with the treatment and/or prevention of various diseases, including cancer. Dating back to the 1940’s, natural treatments such as medicinal herbs and plant materials have been used as a form ...
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Regulation of autoimmune and anti‐tumour T‐cell responses by PTPN22
... genetically-engineered tumour-reactive T cells or ex vivo expanded tumour-infiltrating lymphocytes (TILs) has had substantial success as a cancer immunotherapy ...of anti-tumour ...cell ...
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Mechanisms of anti-tumour immune stimulation following GDEPT
... irradiated tumour cells have been undertaken (Tepper, ...releasing tumour debris and soluble antigen and therefore favouring the development of anti-tumour immunity through cross-priming ...
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Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer.
... and anti-tumour therapy in the context of HCV-HCC is sup- ported by our fi nding that the virus can access normal liver tissue as well as tumours, following intravenous delivery in ...a tumour ...
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Structure activity correlation studies of anti tumour agents based on flavone acetic acid
... the calculated bond lengths involving carbon is about 0.002 Â [69]. However it is interesting to note that some of these differences are positive while other aie negative and some coiTelation with the anti ...
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Scientific Validation of Siddha Herbo- Metallic Formulation Kandha Rasa Villai to Evaluate the Efficacy of it’s Anti- Cancer, Anti- Tumour and Anti- Oxidant Activities.
... This is to certify that the dissertation entitled Scientific Validation of Siddha Herbo- metallic Formulation “Kandha Rasa Villai” to Evaluate the Efficacy of its Anti-Cancer, Anti- Tumour and ...
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The Mechanism of Action of Anti-tumour Platinum Compounds2-15
... I n this article we discuss the evidence for the mechanism of action of platinum anti-tumour compounds, beginning with a summary of the types of analogue compound[r] ...
14
Synthesis and anti tumour activity of some new derivatives of flavone 8 acetic acid
... by anti-proliferative or cytotoxic ...causes tumour necrosis by O came from Bibby and Double^^ using normal NMRI, thymectomised mice and nude mice ...
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The chemistry of complex ion anti tumour agents
... The kinetics of the first hydrolysis step of cis-DDP Equation 1.1 have been investigated in acidic media in both the forward and reverse directions using UV spectroscopy to monitor the r[r] ...
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Targeting cellular metabolism using rapamycin and/or doxycycline enhances anti-tumour effects in human glioma cells
... antibodies: anti-phospho- mTOR (Ser2448) (p-mTOR; 1:1000; #2971, Cell Sign- aling Technology—CST), anti-mTOR (mTOR; 1:1000; #2972, CST), anti-phospho-S6 (Ser 235/236) (p-S6; 1:1000; #4858, CST), ...
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Scientific Validation of Anti -Oral Cancer, Anti-Tumour, Antimicrobial Activities of Siddha Metallo-Mineral Formulation Kaalamega Narayana Chendhooram in Cell Line Studies
... Treatment depends on stage, age of the patient, tumour type, location and size. Wide margin resection is the goal, but may not be possible because of the proximity of vital structures. Adjuvant postoperative ...
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