Anticancer Agents
SYNTHESIS, IN VITRO ANTICANCER AND MOLECULAR DOCKING STUDIES OF NEW BISISATINS AS ANTICANCER AGENTS
... In continuation to our study on biologically active isatin derivatives [27-28] , here, we report the synthesis and spectroscopic characterization of some (N 1 Z,N 4 Z)-N 1 ,N 4 -bis(2-oxoindolin-3- ylidene) ...
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Organoiridium complexes : anticancer agents and catalysts
... thought to be kinetically inert, but this is not always the case. Their reactivity is strongly dependent on the ligand set. Ligand exchange reactions of some organoiridium Cp * complexes, for example, can take place in ...
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RECENT ADVANCES IN THIOSEMICARBAZONES AS ANTICANCER AGENTS
... M.D. Altintop et al (2015); synthesized fourteen new naphthalene-based thiosemicarbazone derivatives and evaluated as new anticancer agents against LNCaP prostate cancer cells. MTT assay indicated that ...
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Synthesis, Characterization and Evaluation of Isoniazid Analogues as Potent Anticancer Agents
... newer anticancer agents will remain an important challenging task for medicinal chemists 7 ...toxic agents which ideally shorten the duration of therapy and are effective against cancer 8 ...for ...
7
37. Herbal medicinal plants as an anticancer agents
... Cancer is known to be the second most common cause of death, surpassed only by cardiovascular disease. So there has been intense research on various plant resources to develop novel anticancer agents. From ...
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COMBINATION OF HETEROCYCLIC COMPOUNDS: AS ANTICANCER AGENTS
... and anticancer activity of 2-anthryl substituted benzimidazole derivatives, New Journal of Chemistry, 2015, ...as anticancer agents, international journal of pharmaceutical and applied sciences, ...
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Synthesis and Biological Evaluation of Novel Homopiperazine Derivatives as Anticancer Agents
... new anticancer agents, a series of novel 1-benzhydryl-4-(substituted phenylcarboxamide/carbothioamide)- 1,4-diazepane derivatives were designed, synthesized and characterized using 1H NMR, LCMS and ...
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A REVIEW: HERBS USED AS ANTICANCER AGENTS
... - Anticancer Agents: A grass obtained from the plant Cymbopogen citrates belongs to the family citronella, lemon grass as an herb has been used for centuries for its positive health ...promising ...
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Histone deacetylase inhibitors (HDACIs): multitargeted anticancer agents
... HDACIs are a promising new group of anticancer agents that have shown positive responses in preclinical and clinical trials. HDACIs have been shown to induce malignant cell death over a large range of solid ...
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CHALCONES AS A PRINCIPLE PHARMACOPHORE FOR DESIGN & DEVELOPMENT OF NOVEL ANTICANCER AGENTS
... Chalcones/1,3–diphenyl-2-propene-1-one/benzalacetophenone, are the name of structurally related same compound containing two aromatic rings conjunct via bridge system enveloping carbon and keto-ethylenic moiety, ...
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Design and synthesis of certain novel bicoumarin derivatives as anticancer agents
... including anticancer[4, 5], anti-HIV [6], anti-inflammatory [7, 8], analgesic [8], antituberculosis [8], antibacterial [8],antioxidant [9], anticoagulant[10],and antimicrobial ...their anticancer effects ...
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Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents
... of anticancer agents may be hindered by low solubility in water, poor permeability, and high efflux from ...these agents in cancer treatment, with higher efficacy and fewer side ...
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Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview
... useful anticancer agents. In different region of Chhattisgarh many traditional healers use various medicinal plants for treating of various cancer. This review revealed that many of medicinal plants used by ...
11
Natural and synthetic coumarins as potential anticancer agents
... Treatment for NSCLC often fails because of drugs insusceptibility to advanced lung cancer stages [38]. Many coumarin derivatives, natural and synthetic have proven to be excellent anticancer agents on this ...
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Alkaloids as anticancer agents
... Alkaloids play major role as anticancer agents by inhibiting the enzyme topoisomerase which is involved in DNA replication, inducing apoptosis and expression of p53 gene. Although they undoubtedly existed ...
8
In-silico molecular design of heterocyclic benzimidazole scaffolds as prospective anticancer agents
... Benzimidazole is a valuable pharmacophore in the field of medicinal chemistry and exhibit wide spectrum of biologi- cal activity. Molecular docking technique is routinely used in modern drug discovery for understanding ...
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Arene Ruthenium(II) Thiosemicarbazone complexes as anticancer agents
... For example, the nature of the monodentate ligand Z influences the way in which ruthenium half-sandwich complexes [Ru-Cl] and [Ru-I] of Figure 1.7 are internalised by human ovarian cance[r] ...
236
A Study on Patients' Medication Adherence and Practices with their Oral Anticancer Agents
... The degree of adherence was determined according to the score resulting from the sum of all the correct answers. If the score is 0 they will considered as following high adherence, if it is 1 or 2 points average ...
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Vepris nobilis plant: a potential source of anticancer agents
... Background: Cancer is one of the major causes of death worldwide. Current cancer therapy is costly, it has poor therapeutic outcomes and many side effects. Therefore, new medications are needed. Plants have been used as ...
5
Synthesis and evaluation of some pyrazoline derivatives as anticancer agents
... Many pyrazoline derivatives are acknowledged to possess a wide range of bioactivities. The pyrazoline motif makes up the core structure of numerous biologically active compounds. Thus, some representatives of this ...
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