anticancer effect
PHYTOCHEMICAL SCREENING AND IN VITRO ANTICANCER EFFECT OF EXTRACTS ENTANDROPHRAGMA ANGOLENSE A MEDICINAL PLANT USED IN THE TREATMENT OF OBSTETRIC FISTULA IN IVORY COAST
... every year 50000 in Africa and 150 000 in Asia. In West Africa, 5000 new cases of obstetric fistula are reported annually (Zeinab et al., 2003).Although difficult delivery is the leading cause of vesico-vaginal fistula, ...
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Albumin binding and anticancer effect of magnesium oxide nanoparticles
... The MgO NPs demonstrated strong binding affinity through hydrophobic interactions with HSA molecules. It was revealed that MgO NPs induced marginal secondary struc- tural changes in HSA molecule. The MgO NPs also ...
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STUDY ON ANTICANCER EFFECT OF SYNTHETIC BIOGENIC SOURCE OF GERMACRENE A
... can not get inside the cells; While the cells that lose activity or incomplete cell membranecan be dyed blue by trypanblue because the permeability of the membrane increases, It can be considered that the cell has died ...
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Folic acid-conjugated mesoporous silica nanoparticles for enhanced therapeutic efficacy of topotecan in retina cancers
... cytotoxic effect of blank NP was studied in Y79 cancer ...of anticancer agents were studied in Y79 cancer ...cytotoxic effect in the cancer ...higher anticancer effect in the cancer ...
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Cisplatin-loaded superparamagnetic nanoparticles modified with PCL-PEG copolymers as a treatment of A549 lung cancer cells
... an anticancer medicine and the effect of nanocapsulated cisplatin has been studied in lung cancer (A 549 ) cell ...cytotoxic effect and were biocompatible. The anti-proliferative effect of ...
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Efficient intravesical therapy of bladder cancer with cationic doxorubicin nanoassemblies
... Abstract: Nanoparticles have promising applications in drug delivery for cancer therapy. Herein, we prepared cationic 1,2-dioleoyl-3-trimethylammonium propane/methoxypoly (ethyl- eneglycol) (DPP) nanoparticles to deliver ...
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Catalytic nanomedicine technology: copper complexes loaded on titania nanomaterials as cytotoxic agents of cancer cell
... the anticancer effect of novel agent ...cytotoxic effect of Cu(acac) 2 and Cu(Oac) 2 , alone as well as loaded on TiO 2 ...toxic effect was determined by comparison with the toxic ...
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Proteomic response to 5,6-dimethylxanthenone 4-acetic acid (DMXAA, vadimezan) in human non-small cell lung cancer A549 cells determined by the stable-isotope labeling by amino acids in cell culture (SILAC) approach
... the effect and poten- tial molecular targets of DMXAA on cell cycle distribution in A549 cells, we treated A549 cells with 10 µ M DMXAA for 24 hours and then subjected samples of the cells to quan- titative ...
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Pramlintide, an antidiabetic, is antineoplastic in colorectal cancer and synergizes with conventional chemotherapy
... the anticancer effect of this agent is dependent on the p53 status; HCT-116 cell lines express p53 in wild-type conformation, while in HT-29 there is a G to A mutation in codon 273 of the gene that results ...
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Journal of Applied Pharmaceutical Science
... invitro anticancer effect of leaves of Alstonia scholaris, using the cytosolic marker enzymes like AST, ALP, ACP, LDH, γ-GT, and 5'-NT In vitro over breast cancer ...
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Astragalus polysaccharides (PG2) enhances the M1 polarization of macrophages, functional maturation of dendritic cells, and T cell-mediated anticancer immune responses in patients with lung cancer
... Lung cancer is one of the most frequently diagnosed malignancies and the leading cause of cancer death worldwide, with an estimated 234,030 new cases diagnosed and 154,050 deaths in the United States alone in 2018 ...
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Ergosterol peroxide activates Foxo3-mediated cell death signaling by inhibiting AKT and c-Myc in human hepatocellular carcinoma cells
... the anticancer effect of the synthetic ergosterol peroxide, we performed cell proliferation assay followed by treating the human hepatocellular carcinoma cell lines HepG2, JHH-1 and SNU-449 with different ...
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Curcumin: the spicy modulator of breast carcinogenesis
... natural anticancer agent for this ...modulatory effect of curcumin on the cancer hallmarks. The focus is its anticancer effect in the complex pathways of breast ...its effect on cell ...
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Biochemical indicators of nephrotoxicity in blood serum of rats treated with novel 4-thiazolidinone derivatives or their complexes with polyethylene glycol-containing nanoscale polymeric carrier
... Thus, the levels of total protein, urea, creati- nine, glucose, ions of iron, calcium, sodium and chloride in blood serum of the experimental rats un- der the influence of investigated synthetic derivatives of the ...
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Extracts and components of <em>Ficus carica</em> leaves suppress survival, cell cycle, and migration of triple-negative breast cancer MDA-MB-231 cells
... Results: We investigated the mechanism of anti-growth effects, and found that the expres- sions of genes that promote apoptosis were increased. In addition, the treated cells illustrated increased portion at S phase and ...
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Novel Hyaluronic Acid Conjugates for Dual Nuclear Imaging and Therapy in CD44-Expressing Tumors in Mice In Vivo
... Hyaluronic acid, a natural CD44 receptor ligand, has attracted attention in the past years as a macromolecular delivery of anticancer agents to cancer. At the same time, the clinical applications of Gemcitabine ...
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EFFECT OF SOLANUM CHRYSOTRICHUM SCHLDL ON CELL PROLIFERATION IN VITRO
... ABSTRACT: The effect of four extracts of Solanum chrysotrichum on the proliferation of bacteria, yeasts, mouse spleen cells and human transformed cells was determined. Dry leaves grounded were consecutively ...
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Protective Role of Green Tea Extract Against Genotoxic Damage Induced by Anticancer Drug and Steroid Compound, Separately, in Cultured Human Lymphocytes
... antigenotoxic effect of Green tea extract (GTE), against genotoxic damage induced by a steroid Trenbolone and an anticancer drug Docetaxel in cultured human lymphocytes, both in absence and presence of ...
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Teng Long Bu Zhong Tang, a Chinese herbal formula, enhances anticancer effects of 5 Fluorouracil in CT26 colon carcinoma
... Angiogenesis, the process of new blood vessel gener- ate from existing vessels, plays a crucial role in tumor growth and metastasis. Angiogenesis has been recog- nized as an impotent therapeutic target for cancer treat- ...
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Designing personalised cancer treatments
... the effect of mevalonate pathway inhibitors was limited, but that they enhanced the effect of N-bisphosphonates, probably via the production of metabolites not normally present in the cell ...
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