Antigenic diversity
Limited antigenic diversity of Plasmodium falciparumapical membrane antigen 1 supports the development of effective multi-allele vaccines
... the antigenic diversity of polymorphic antigens, the level of allele-specific and cross-reactive antibodies, and the relationship between sequence poly- morphisms and antigenic escape are essential ...
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Genetic and Antigenic Diversity of the Surface Protective Antigen Proteins of Erysipelothrix rhusiopathiae
... greatest diversity in Spa proteins was found in the N-terminal half of the molecule (50 to 57% similarity), which was shown to be involved in ...and antigenic diversity in Spa proteins and to ...
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Extent of Antigenic Diversity in the V3 Region of the Surface Glycoprotein, gp120, of Human Immunodeficiency Virus Type 1 Group M and Consequences for Serotyping
... The diversity of the immunogenic V3 loop has also been studied by comparing the amino acids of different isolates, leading to a phenetic classification of at least 14 clusters of sequences, each one characterized ...
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Antigenic diversity of meningococcal outer membrane protein PorA has implications for epidemiological analysis and vaccine design.
... the antigenic variability of the meningococcus, which has evolved numerous genetic mechanisms for generating antigenic variation (14, 28, ...resultant antigenic diversity has, however, been ...
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Rapid Detection of Antigenic Diversity of Akabane Virus Isolates by Dot Immunobinding Assay Using Neutralizing Monoclonal Antibodies
... that antigenic variation exists in field isolates of AKA virus in Japan; in particular, the Iriki strain of AKA virus, isolated in 1984, shows low cross-reactivity with the JaGAr39 strain (prototype strain of AKA ...
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Antigenic Diversity of Haemophilus somnus Lipooligosaccharide: Phase Variable Accessibility of the Phosphorylcholine Epitope
... undergoes antigenic phase variation, which may facilitate evasion from the bovine host immune response and/or colonization and ...LOS antigenic diversity in ...investigate antigenic variation ...
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Crystal Structure of an Aquabirnavirus Particle: Insights into Antigenic Diversity and Virulence Determinism
... limited antigenic diversity, antibody neutralization escape mutations map to positions 222 and 223 (loop P BC ), 251 (P DE ), and 313 and 322 (P HI ) ...
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Antigenic Diversity and Immune Evasion by Malaria Parasites
... sequence diversity in subtelomeric variant genes were recently provided by Freitas-Junior and colleagues (40), who detected nonparental var gene alleles in the progeny of a genetic cross between ...huge ...
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The global antigenic diversity of swine influenza A viruses
... the antigenic evolution of human-origin viruses in swine was via long and divergent evolutionary paths from those observed in ...the antigenic diversity of influenza viruses in ...the ...
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Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development
... preexisting antigenic diversity, population structure, the likelihood of coinfection by genetically distinct strains, and the efficiency of ...genomic diversity and population structure have been ...
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A stochastic model with antigenic diversity threshold of hiv transmission using geometric process
... This study is based on a stochastic model for predicting the seroconversion time of HIV transmission using intercontact time between successive contacts to be a geometric process. In this study of HIV infection the ...
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The effects of a partitioned var gene repertoire of Plasmodium falciparum on antigenic diversity and the acquisition of clinical immunity
... clonal antigenic variation ...sequence diversity of var genes facilitates the sequential reinfection of hosts, with the antigenic pro- file of newly infecting parasites appearing to correspond to a ...
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Absence of antigenic diversity in Pf155, a major parasite antigen in membranes of erythrocytes infected with Plasmodium falciparum
... b A is Liberian donor A; IgG was affinity purified on F32-infected erythrocytes; 33G2 is human monoclonal antibody IgM; MoMAb, is mouse monoclonal antibody IgGl against synthetic octapep[r] ...
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Antigenic Diversity and Distribution of Rabies Virus in Mexico
... the diversity of variants found in nonreservoir species and thus an approximate esti- mate of the potential risk of humans acquiring rabies from the specific reservoirs of the variants ...
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Monoclonal antibodies to Legionella Mip proteins recognize genus- and species-specific epitopes.
... Besides the implications for organism identification, the knowledge about the immunological specificity of the Mip pro- teins is usable in serologic diagnosis. Traditionally, the detec- tion of antibodies in patient sera ...
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Vol 2, No 7 (2011)
... to antigenic diversity increases then E(T) increases very ...to antigenic diversity in successive contacts is less and so it takes more time for ...
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Are Eimeria Genetically Diverse, and Does It Matter?
... antigenic diversity of Eimeria species which infect chickens in the context of vaccine 47.. development and the potential for future successes based on new sequencing 48.[r] ...
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Antigenic and Genomic Diversity of Human Rotavirus VP4 in Two Consecutive Epidemic Seasons in Mexico
... In the several genotyping studies conducted worldwide, ge- notypes P[4] (associated with a VP7 protein with G2 specific- ity) and P[8] (associated with the G1, G3, or G4 VP7 protein) have emerged as the most frequent ...
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Single Hemagglutinin Mutations That Alter both Antigenicity and Receptor Binding Avidity Influence Influenza Virus Antigenic Clustering
... that antigenic positioning of viral isolates is influ- enced, at least in part, by changes in viral receptor binding ...an antigenic cluster transition be- tween 1992 and 1995 in conventional ...
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Phylogenetic, antigenic and biological characterization of pigeon paramyxovirus type 1 circulating in China
... PPMV-1 isolates tended to develop a symbiotic relation- ship with pigeons so that infected pigeons showed no symptoms, became healthy carriers and shed occasionally. Previous studies showed that the same PPMV-1 strains ...
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