antigenic evolution
Reemergence of Enterovirus 71 in 2008 in Taiwan: Dynamics of Genetic and Antigenic Evolution from 1998 to 2008
... genetic evolution of the VP1 protein coding region may contribute to antigenic diversity of the ...the antigenic properties of EV71 that circu- lated in Taiwan, we selected strains representing ...
10
Rules of co-occurring mutations characterize the antigenic evolution of human influenza A/H3N2, A/H1N1 and B viruses
... Here, we propose a method based on association rule mining [31] to identify co-occurring patterns of multiple-site mutations. Association rule mining has been shown as a promising technique in bioinformatic analysis [32, ...
12
Substitutions near the Hemagglutinin Receptor-Binding Site Determine the Antigenic Evolution of Influenza A H3N2 Viruses in U.S. Swine
... HA evolution seen in humans, pigs, and horses (see Table S4 in the supplemental material for direct comparison of observed substitutions in three host ...with antigenic-cluster-defining substitutions in all ...
12
Diversifying Selection Analysis Predicts Antigenic Evolution of 2009 Pandemic H1N1 Influenza A Virus in Humans
... genetic evolution approach without considering phylogenetic relation- ships between viruses as our approach does ...the antigenic evolution of the H1N1 FIG 6 Diversified B-cell/Ab epitopes ...
14
Antigenic evolution of H3N2 influenza A viruses in swine in the United States from 2012 to 2016
... 1358 swine H3 HA protein sequences isolated between 2012–2016 in the United States were downloaded from the Influenza Research Database (IRD) 14 on July 3, 2017. Viruses that were not C-IV or were identified as a ...
25
Antigenic Evolution of Vaccine-Derived Polioviruses: Changes in Individual Epitopes and Relative Stability of the Overall Immunological Properties
... the antigenic sites as well as marked alteration of the specificity of individual epitopes might suggest that these phenomena were the results of im- mune response ...
13
Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine
... putative swine vaccine sera to human seasonal H3N2 strains were over 4 antigenic units in viruses 320. isolated since 1995, and a seasonal strain isolated from humans in 2011 (A/Victori[r] ...
36
Monitoring the antigenic evolution of human influenza A viruses to understand how and when viruses escape from existing immunity
... In order to monitor worldwide influenza epidemics, WHO has developed a global tool (FluNet, http://www.who.int/ flunet) to publically disseminate epidemiological and viro- logical information. In addition, Flutrends ...
6
Dynamics of Evolution of Poliovirus Neutralizing Antigenic Sites and Other Capsid Functional Domains during a Large and Prolonged Outbreak
... poliovirus evolution is offset by strong selection against amino acid replacement at most positions of the ...apparent antigenic stability of poliovirus obscures a dynamic of continuous change within the ...
17
Mapping Enterovirus A71 Antigenic Determinants from Viral Evolution
... display antigenic drift to escape vaccine-mediated immunity (28, 29), they are often observed to have evolving antigenic properties ...in antigenic sites for the evolution of en- teroviruses ...
7
Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States
... by antigenic cartography to evaluate potential concurrent antigenic ...significant antigenic distance from previously tested viruses (Lorusso et ...2011). Antigenic drift of IAV is frequently ...
10
Antigenic and Genetic Evolution of Equine Influenza A (H3N8) Virus from 1968 to 2007
... an antigenic cluster and that often the rec- ommendation to update vaccines was made just after the emer- gence of the new cluster or when it was recognized that two different antigenic variants, or two ...
8
Antigenic and Genetic Evolution of Swine Influenza A (H3N2) Viruses in Europe
... 1990s, antigenic drift had occurred, away from A/Port Chalmers/1/73, the strain commonly used in influenza vaccines for ...displayed antigenic and genetic changes similar to those observed in Northern ...
8
Antigenic Divergence of Bordetella pertussis Isolates in Taiwan
... In previous reports, no high degree of correlation between the PFGE type and the combination of ptxS1 and prn alleles was found in Canadian and U.S. B. pertussis isolates (3, 25). In Japan, there was a correlation ...
5
Antigenic and Receptor Binding Properties of Enterovirus 68
... of antigenic differences due to geographical distance is minimal, since the previous studies from other parts of the world identified strains with VP1 sequences similar to those detected in our study in Asia, ...
11
Mapping Antigenic Epitopes on the Human Bocavirus Capsid
... HBoV antigenic footprints overlap those of other Parvoviri- nae ...HBoV antigenic epitopes to those reported for other well-characterized members of the subfamily Parvovirinae revealed similarities and ...
11
The Antigenic Structure Characterization of Oestrus Ovis Larvae
... Analyzing the obtained results can be observed that all protein fractions from total soluble larval antigens are distributed in 27-80 kDa domain. The same fractions (with small formula weights differences, owed to ...
5
Antigenic variation among strains of Chlamydia pneumoniae
... Serum from the patient infected with CWL-050 reacted weakly with strains CWL-029 and CM-1 to form only a single 50-kDa band, but it formed patterns of bands when it was reacted with anti[r] ...
5
A STABILIZER OF ANTIGENIC PHASES IN SALMONELLA ABORTUS-EQUI
... The phase-1 antigen type of a stable phase-2 strain was determined by linked transduction of Fla,+ and H I from that strain to S.. The hidden phase-1 antigen type of the stab[r] ...
5
Antigenic Diversity and Immune Evasion by Malaria Parasites
... huge antigenic diversity seen in PfEMP-1 (and perhaps in other ...both antigenic variation that involves no change in the para- site’s genome and the generation of new alleles by frequent ectopic ...
9