Antitumor Activity
Antitumor Activity of Py-lm Polyamides
... The work presented here focuses on the characterization of Py-Im polyamides as non- genotoxic antitumor agents that are active against prostate cancer xenografts. Chapter 2 details the pharmacokinetic and animal ...
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Fungus-mediated synthesis of silver nanoparticles and evaluation of antitumor activity
... The antitumor activity of nanoparticles and silver is suggested to induce their toxicity through oxidative stress and inflammation by generating reactive oxygen species (ROS) involved in a variety of ...
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Antioxidant, antimicrobial and antitumor activity of genus Opuntia Spp
... and antitumor activities, in scientific databases, such as Scielo, LILACS, PubMed and CAPES/MEC Periodicals, using Opuntia ...Antioxidant activity, Opuntia spp. AND Antimicrobial activity and Opuntia ...
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Synthesis and in vitro antitumor activity of new benzothiazole and benzoxazole derivatives
... and antitumor [6-8] ...cytotoxic activity. [9,10] 2-phenylbenzothiazoles showed its antitumor activity by resembling the ATP antagonistic effects of the natural ...potent antitumor ...
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Preclinical evaluation of biomarkers associated with antitumor activity of MELK inhibitor
... OTS167 was developed as a MELK kinase inhibitor with potent and selective antitumor activity without any obvious toxicity at the effective dose in our preclinical study. MELK is specifically and frequently ...
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ANTITUMOR ACTIVITY OF CRATEVA MAGNA IN TRANSPLANTABLE TUMOR MODELS IN MICE:
... antipyretic activity on TAB-VACCINE induced pyrexia in ...antinociceptive activity in ...vitro antitumor activity of leaves of CM has not reported so ...the antitumor activity of ...
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Evaluation of the Antitumor Activity of Dacomitinib in Models of Human Bladder Cancer
... the antitumor activity of dacomitinib in human bladder cancer cell lines express- ing varying levels of HER family ...dacomitinib activity in ...superior antitumor effects compared with ...
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Quercetin: Antitumor activity and pharmacological manipulations for increased therapeutic gains
... daily. Antitumor activity was determined by the basis of median survival time (MST) of treated (T) and control (C) groups and expressed as percent T/C ...of activity 15 ...
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Safety and antitumor activity of recombinant soluble Apo2 ligand
... Antitumor activity of Apo2L in vitro. To explore the activity of Apo2L against a spectrum of cancer cell types, we tested its effect in vitro on the growth of 39 different cell lines derived from ...
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Effect of Magnesium Supplementation to Prevent Nephrotoxicity on the Antitumor Activity of Cisplatin
... In this study, we determined the transporter expression, intracellular accumulation, and antitumor activity of CDDP in cells supplemented with Mg. Although Mg exposure increased MATE1 mRNA levels, it did ...
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<p>Synthesis and antitumor activity of novel pyridinium fullerene derivatives</p>
... While there were no signi fi cant differences in in vitro antiproliferative activity against A549 among 10, 13 and cis- 14, 13 showed the most potent antitumor activity in vivo. In addition, 1 showing ...
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Antitumor activity of a folate receptor-targeted immunoglobulin G-doxorubicin conjugate
... Abstract: Development of antibody-drug conjugates (ADCs) is a promising therapeutic strategy for cancer therapy. In this study, folate was conjugated via a polyethyleneglycol (PEG) linker to immunoglobulin G (IgG), which ...
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Antitumor Activity of Disintegrin Like Components from the Venom of Montivipera raddei
... Our findings represent the first report of the antitumor activity of the disintegrin-like components from the venom of Armenian viper (M. raddei). The venom of M. raddei was separated by reverse phase ...
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Antitumor Activity of Alloy and Core Shell Type Bimetallic AgAu Nanoparticles
... biological activity, NPs were tested for an antitumor activity depending on metal molar ratios (Ag:Au = 1:1; 1:3; 3:1) and topological dis- tribution of gold and silver within NPs (Au core Ag shell ...
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Antitumor activity of silver nanoparticles biosynthesized by micro algae
... The antitumor activity of AgNPs synthesized by algal extracts was determined in vitro against Ehrlich Ascites Carcinoma (EAC) cell line which was kindly purchased from the National Cancer Institute, Cairo ...
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Zinc oxide nanocomposites with antitumor activity
... with antitumor activity were obtained by deposition of ZnO nanofilms on surfaces of ethyl ether Salicyli- dene DL-tyrosine (S1) and ethyl ether Salicyli- dene DL-tyrosine Cu (II) chelate (S2) by magne- tron ...
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Antitumor Activity of Methanolic Extract of Pisonia Aculeata Leaf
... the antitumor activity of methanolic extract of Pisonia aculeata leaves extract on Ehrlich Ascites Carcinoma (EAC) in ...The antitumor effect of the extract was evaluated by using survival time, ...
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Enhanced antitumor activity of realgar mediated by milling it to nanosize
... administration of the two realgar preparations, with different particle sizes are presented in Figure 9. After intragastric admin- istration of realgar NPs and coarse realgar, arsenic was rapidly distributed in different ...
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A phosphotyrosine switch determines the antitumor activity of ERβ
... The 2 estrogen receptors ERα and ERβ mediate diverse effects of estrogens in multiple tissues (1). Despite considerable sequence homology, ERα and ERβ carry out nonredundant physiological functions. While ERα is critical ...
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Antitumor activity of methanolic extract of Cyclea peltata
... The present study was carried out to evaluate the antitumor activity of MECP on DAL induced mice model. Inoculated mice treated with 100 and 200 mg/kg of MECP showed significant increase in life span. The ...
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