antitumor effect
Triclosan treatment decreased the antitumor effect of sorafenib on hepatocellular carcinoma cells
... performed. As shown in Figure 7A, the intrahepatic growth of HCC cells in mice liver was identified by PET/CT screening. As expected, TCS enhanced the PET imaging in liver location compared with solvent control, whereas ...
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Antitumor effect of a new nano-vector with miRNA-135a on malignant glioma
... The antitumor effect of mPEG-g-PEI/ miR-135a to C6 was confirmed in vivo by MR scanning, pathology and survival ...uptake effect of both normal glial and glioma ...
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Study of Antitumor Effect of Methanolic and Aqueous Extracts of Allium Stivum L. (Garlic) Cloves Using Potato Disc Bioassay
... the antitumor effect of the methanolic and aqueous extract of garlic was tested using potato disc ...revealed antitumor activities in potato disc ...
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Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway
... proapoptotic effect of andrographolide and TP was assessed by measuring the expression of cleaved PARP, caspase-9, pro-caspase-3, and cleaved ...significant effect upon ...
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Antitumor effect of lysine-isopeptides
... The effect of the compounds was tested on a human erythroleukemia cell line (K-562) and on four transplantable mouse tumors (L1210 lymphoid leukemia, P38 macrophage derived tumor, Ehrlich ascites carcinoma, Lewis ...
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Sonodynamic Antitumor Effect of Benzoporphyrin Derivative Monoacid Ring A on KLN205 Cells
... Recently, it was reported that a mechanism for the sonodynamic activation of sonosensitizer might be at- tributed to the enhancement of active oxygen generation through acoustic cavitation [21,22]. It has been proposed ...
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Antitumor effect of TW-37, a BH3 mimetic in human oral cancer
... To evaluate the efficacy of in vivo antitumor activity of TW-37, we used a xenograft mice model by subcutane- ously injection of HSC-3 cells into the flank of athymic nude mice. As shown in Fig. 4a and b, TW-37 ...
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Antitumor effect of Kanglaite® injection in human pancreatic cancer xenografts
... KLT has an inhibitory effect on many types of tumors [7]. In our study, after treatment with KLT for 21 days, the tumor volumes in KLT-treated groups were consid- erably lower than those in the control group (P ...
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Photodynamic Therapy Using Novel Zinc Phthalocyanine Derivatives and a Diode Laser for Superficial Tumors in Experimental Animals
... photodynamic effect in vitro and in vivo was ...vivo antitumor effect of βCD-4TFEO-Pc against B16-F10 cells transplanted on to the chorioallantoic membranes of chick- embryos was ...
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COMPARATIVE STUDY ON THE EFFECT OF NANO CURCUMIN COMPLEXES AS ANTITUMOR IN MICE
... Drug conveyance frameworks utilizing nanoparticles are appreciated as a promising methodology for enhancing the safety and bioavailability of curcumin. The basic aim of the present study was to compare the efficacy of ...
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Inhibition of oleandrin on the proliferation and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway
... an antitumor effect on many tumor cells including breast cancer, lung cancer as well as leukemia ...selective antitumor and chemora- diation sensitization properties ...
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Effect of Magnesium Supplementation to Prevent Nephrotoxicity on the Antitumor Activity of Cisplatin
... Abstract: Background: Cisplatin (CDDP) is one of the most widely used anticancer drugs, but CDDP often leads to nephrotoxicity, which limits its clinical effectiveness. Magnesium (Mg) supplementation is recommended for ...
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Efficient inhibition of lung cancer in murine model by plasmid-encoding VEGF short hairpin RNA in combination with low-dose DDP
... Having confirmed the specificity and potency of the VEGF shRNA, we then combined it with DDP in an ani- mal model to investigate the antitumor efficacy of the combination treatment. We used a nude mice model to ...
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<p>Formulation, Preparation and Evaluation of Nanostructured Lipid Carrier Containing Naringin and Coix Seed Oil for Anti-Tumor Application Based on “Unification of Medicines and Excipients”</p>
... fold and 1.52-fold lower relative to that of free drug, NDNLCs and NONLCs, respectively. The signi fi cant dif- ference (P< 0.05) in antiproliferative activity between the NCNLCs and free drug, shown that the NLC ...
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<p>miR-3609 Decelerates the Clearance of Sorafenib in Hepatocellular Carcinoma Cells by Targeting EPAS-1 and Reducing the Activation of the Pregnane X Receptor Pathway</p>
... only antitumor drugs available for advanced ...the antitumor effect of molecular targeting agents on HCC cells (Figure ...the antitumor effect of molecu- lar targeting agents on HCC ...
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Effect of a controlled-release drug delivery system made of oleanolic acid formulated into multivesicular liposomes on hepatocellular carcinoma in vitro and in vivo
... Abstract: The aim of the present study was to develop a novel dosage form of multivesicular liposomes for oleanolic acid (OA) to overcome its poor solubility, prolong therapeutic drug levels in the blood, and enhance the ...
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Antitumor activity of tripterine via cell-penetrating peptide-coated nanostructured lipid carriers in a prostate cancer model
... the antitumor activity of CT-NLC further in vivo, we constructed a mouse model of prostate cancer using RM-1 ...higher antitumor activity of CT-NLC and T-NLC may be attribut- able to the following: the ...
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ANTICANCER ACTIVITY OF METHANOL EXTRACT OF SESUVIUM PORTULACASTRUM L. WHOLE PLANT AGAINST EHRLICH ASCITES CARCINOMA (EAC)Sheela .D and Uthayakumari Kalavathy*DOWNLOAD/VIEW
... the antitumor activity of methanol extract of Sesuvium portulacastrum whole plant (Family: Aizoaceae) on EAC model in Swiss Albino ...the antitumor effect of methanol extract of whole plant of ...
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In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizes
... and antitumor efficacy in vitro and in ...the antitumor effect of SN-38 markedly compared to SN-38 solution and SN-38/NCs-B whose particle size was ...better antitumor effects than treatment ...
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Journal of Applied Pharmaceutical Science
... the antitumor activity of ethanol extract of whole plant of Polygala rosmarinifolia on DAL model in Swiss Albino ...the antitumor effect of ethanol extract of whole plant of Polygala rosmarinifolia ...
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