Antiviral Drug
Antiviral Drug Discovery by Targeting the Envelope Glycoproteins of Influenza A Virus
... for antiviral drug ...newer antiviral compounds for the prevention of future pandemic and resistant strains of influenza A viruses targeting the surface ...of antiviral compounds of influenza ...
10
Additive Effect of Neutralizing Antibody and Antiviral Drug Treatment in Preventing Virus Escape and Persistence
... the antiviral drug ribavirin as a single agent has been reported to reduce the viral burden of several RNA viruses or at least to diminish clinical symptoms after infection (26, 28, 53, ...in ...
6
An antiviral drug combinational study against Hepatitis B virus – A computational drug repositioning approach
... an antiviral drug combination studies against Hepatitis B ...and Drug administration-approved drugs (1491) against three protein targets; through structural- and ligand-based pharmacophores screening ...
8
Differential Transmission of Antiviral Drug-Resistant Chikungunya Viruses by Aedes Mosquitoes
... of antiviral drug-resistant CHIKV by Aedes ...broad-spectrum antiviral that is currently approved in Japan to treat influenza virus infections ...
13
An antiviral drug combinational studies against hiv- a computational drug repositioning approach
... This study was aimed at identifying two promising generic drugs and conduct an antiviral drug combination studies against HIV. It has two components; computational and in-vitro studies. The computational ...
7
The Synthetic Antiviral Drug Arbidol Inhibits Globally Prevalent Pathogenic Viruses
... ARB inhibited members of both Filoviridae and Arenaviridae, which are known to cause lethal hemorrhagic fevers in humans. It is noteworthy that ARB has been used clinically for decades in other countries, with minimal ...
7
An antiviral Drug combinational studies against Lassa virus- A computational drug repositioning approach
... This study was aimed at identifying two promising generic drugs and conduct an antiviral drug combination studies against Lassa virus. It has two components; computational and in-vitro studies. The ...
12
Combination of an Antiviral Drug and Immunomodulation against Hepadnaviral Infection in the Woodchuck Model
... Several studies of therapeutic vaccinations have been carried out in the woodchuck model (reviewed in references 24, 25, 34, and 35) and demonstrated collectively that B- or T-cell re- sponses to viral antigens could be ...
6
Virus-host interactomics: new insights and opportunities for antiviral drug discovery
... Conventional drug therapies against human viruses mainly target viral enzymes (Table ...limitations, antiviral drug discov- ery is beginning to explore the possibility to develop host-oriented ...
14
The antiviral drug ribavirin reversibly affects the reproductive parameters in the male Wistar rat
... drugs [18]. Reports are available, which reveal its toxicity on haematological parameters and, there- fore, induced abnormal clinical conditions in both animals and humans [1]. Recently, the suppressing effects of ...
7
Effect of Superdisintegrants Concentration on Dissolution Profile of Poorly Soluble Antiviral Drug
... R.V.S. College of Pharmaceutical Sciences,Coimbatore Page 5 excipients include among others diluents, binders, lubricants, glidants and disintegrants. Diluents are used to impart bulk to the formulation to make a tablet ...
97
DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL MICROEMULSION GEL FOR AN ANTIVIRAL DRUG
... Microemulsion appears to have the ability of deliver larger amount of topically applied agents into the mucosa than the traditional gel & creams. Microemulsions are defined as thermodynamically stable transparent, ...
18
Insertional protein engineering for analytical molecular sensing
... designing antiviral drugs that inhibit viral protein processing and therefore ...for antiviral drug testing and evaluation of the enzyme ...for antiviral drug research but also to ...
7
Clinical and Pharmacological Approaches to Optimize Outpatient Treatment of Bronchial Asthma
... the drug should consider any negative consequences, in particular, drug ...to antiviral drug with immunomodulatory activity, according the mechanism of ...a drug used exactly for asthma ...
7
Structure-based mechanism of proton transport through the influenza A M2 protein
... Influenza A/M2 is a minimalistic integral membrane protein that mediates proton transport across the viral membrane and is of interest as an antiviral drug target. This protein has been extensively studied ...
228
Drug Repurposing in Antiviral Research: A Current Scenario
... industry, drug repur- posing is the best solution for reducing the risks in the pipeline of new drug ...the drug repurposing approach which targets host functions is a time and cost-effective route ...
5
Epidemiology, patient profile, and health care resource use for hepatitis C in Italy
... and antiviral drug characteristics, and to estimate the health care consumption rates and related costs for the management of patients affected by hepatitis C virus (HCV) infection by using data from ...
8
Search | Preprints
... Till now, no approved effective antiviral drug or vaccine has been developed against SARs- CoV2 (COVID-19). Scientists of many private companies and Government institutional laboratories of some countries ...
36
Poliovirus 2C region functions during encapsidation of viral RNA.
... an antiviral drug that inhibits the replication of poliovirus in ...of drug addition to infected cells, we found that the drug acts at a stage which is late in the replication cycle and ...
7
In Vitro-Selected Drug-Resistant Varicella-Zoster Virus Mutants in the Thymidine Kinase and DNA Polymerase Genes Yield Novel Phenotype-Genotype Associations and Highlight Differences between Antiherpesvirus Drugs
... to antiviral drug resistance and their impacts on the structures of the viral proteins indicated specific patterns of cross-resistance and highlighted important differences, not only between dis- tinct ...
12