Antiviral effect
Antiviral Effect of Pterocarpus indicus Willd Leaves Extract Against Replication of Dengue Virus (DENV) In Vitro
... In a screening for potential therapeutic agents against DENV, we evaluated leaves extract of P. indicus from Indonesia. The crude extract of P. indicus (Pi) have antiviral effect to DENV with high ...
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Monitoring the Antiviral Effect of Alpha Interferon on Individual Cells
... the antiviral activity of IFN- ␣ against HCV in indi- vidual HCV-infected cells has not yet been investigated due to technical ...anti-HCV effect of IFN- ␣ in individual cells by using a derivative of HCV, ...
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Original Article Non-antiviral effect of entecavir on hepatocellular carcinoma
... antitumor effect on hepatocellular carcinoma (HCC) have not been ...ETV effect on tumor cells were ...tory effect with different concentrations on Huh7 cells which is a human hepatocellular carcinoma ...
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Chemical Composition and Antiviral Effect of Extracts of Origanum vulgare
... tration, serial dilutions were evaluated regarding toxicity in different cell lineag- es. The determination of cytotoxicity is considered important in order to diffe- rentiate cytopathic effect and toxic ...
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Interferon-induced proteins in human fibroblasts and development of the antiviral state.
... The induction of these proteins had features in common with the development of the antiviral effect of interferon, such as i sensitivity to actinomycin D and cycloheximide when these com[r] ...
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Screening for antiviral activity of Actinomycetes isolated from soil sediments
... for antiviral substances has long been conducted in our laboratory with Streptomyces culture ...chemotherapeutic effect against certain virus infections in vivo can be ...the antiviral effect ...
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Virological Control by the CD4-Binding Site Antibody N6 in Simian-Human Immunodeficiency Virus-Infected Rhesus Monkeys
... vivo antiviral activity of N6-LS, alone or in com- bination with the established V3-glycan antibody PGT121, in chronically simian- human immunodeficiency virus (SHIV)-SF162P3-infected ...additive antiviral ...
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Euphorbia Microsciadia Percolation and Soxhlet Extracts Exhibit Antiviral Activity
... it’s antiviral effect to specific compounds in the extract ...the antiviral activity of ...its antiviral component(s) could be achieved, which may be useful in the ...
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Comparison of HCV Plus-and Minus-Strand RNA in PBMCs of Responders and non-Responders of Chronically Infected Patients Receiving Ribavirin and Interferon Therapy
... A potent antiviral effect on hepatitis C viral dynamics in serum and peripheral blood mononuclear cells during combination therapy with high-dose daily interferon a[r] ...
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Interstitial murine cytomegalovirus pneumonia after irradiation: characterization of cells that limit viral replication during established infection of the lungs.
... Even when infection was established in the lungs, as manifested by the presence of infected lung tissue cells in the alveolar septa, an antiviral effect could be assigned to the Lyt-2+, [r] ...
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Virtual Screening of Approved Clinic Drugs with Main Protease (3CLpro) Reveals Potential Inhibitory Effects on SARS-CoV-2
... of binding energy and binding mode, Saquinavir showed similar results to Lopinavir, which can be further compared with the antiviral effect of Lopinavir. Although it is not reported that Thymic Pentapeptide ...
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Isolation and characterization of a small antiretroviral molecule affecting HIV 1 capsid morphology
... displays antiviral effect only when converted to a metabolite by a yet uncharacterized enzyme present in porcine or bovine serum but not in human ...
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Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection
... ABSTRACT Several viruses induce intestinal epithelial cell death during enteric in- fection. However, it is unclear whether proapoptotic capacity promotes or inhibits replication in this tissue. We infected mice with two ...
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Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity
... Many viruses trigger the type I interferon (IFN) pathway upon infection, resulting in the transcription of hundreds of interfer- on-stimulated genes (ISGs), which define the antiviral state of the host. Classical ...
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Identification of a Key Target Sequence To Block Human Immunodeficiency Virus Type 1 Replication within thegag-pol Transframe Domain
... One of the most challenging aspects of the development of antisense or antigene strategies is, in general, to identify the ge- netic targets the expression of which is crucial to the pathological process of disease. ...
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Thalidomide combined with low-dose glucocorticoid in the treatment of COVID-19 Pneumonia
... the effect of thalidomide in blocking NF-κB binding to its target gene promoter, further studies have found that thalidomide combined with dexamethasone could effectively inhibit the excessive inflammatory ...
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INNOVATIVE SCIENTIFIC CONCEPT OF TOPICAL VIRUS GLYCOPROTEIN INHIBITORS INCORPORATED IN HYPEROSMOTIC GLYCEROL REVOLUTIONIZES FUTURE PROSPECTS IN THE TREATMENT OF VIRAL AND BACTERIAL THROAT INFECTIONS
... Related to cytarabine, idoxuridine, trifluridine and vidarabine, acyclovirs are nucleoside analogue antiviral drugs. Like the earlier antivirals, acyclovir only shows activity against some members of the herpes ...
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Extract of Scutellaria baicalensis inhibits dengue virus replication
... Recently, we have shown the novel antiviral activity of pure commercial baicalein against DENV-2 (NGC strain) [18]. Therefore, our current investigations point to the potential use of cold water extract of the ...
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Effect of Different Bio-Enhancers on Antiviral Resistance Inducing Activity of Phytoproteins Obtained from Roots of Boerhaavia diffusa and leaves of Clerodendrum aculeatum
... The antiviral properties of the plant extracts have been shown due to certain novel proteins present in the ...The antiviral potential has been shown to exist in extracts of plants like, Euphorbia hirta ...
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Immune reconstitution in HIV 1 infection : the effects of antiretroviral and immune therapy
... Furthermore, whilst AIDS related malignancies are decreasing, non-AIDS cancers are increasing in prevalence (Simard et al., 2010), and cART itself has now been linked to non-AIDS related conditions, such as ...
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